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APOBEC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2563199

This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
APOBEC1, Polyclonal Antibody
Full Product Name
APOBEC1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
ABEC1; APOBEC 1; APOBEC1; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1; Apolipoprotein B mRNA editing enzyme complex 1; Apolipoprotein B mRNA-editing enzyme 1; BEDP; C->U-editing enzyme APOBEC-1; CDAR1; EC 3.5.4.; HEPR
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.4mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
OMIM
600130
3D Structure
ModBase 3D Structure for P41238
Immunogen
Synthetic peptide of human APOBEC1
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-APOBEC1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-APOBEC1 antibody
IHC: 1:25-1:100
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-APOBEC1 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using APOBEC1 Polyclonal Antibody at dilution of 1:25(×200)
Rabbit Anti-APOBEC1 Polyclonal Antibody – Cat# MBS2563199

Immunohistochemistry (IHC) of anti-APOBEC1 antibody

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using APOBEC1 Polyclonal Antibody at dilution of 1:25(×200)
Rabbit Anti-APOBEC1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2563199

Other Notes

Small volumes of anti-APOBEC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APOBEC1 purchase

MBS2563199 is an antibody targeting APOBEC1. Also known as APOBEC1 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for APOBEC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
APOBEC1 protein, partial
NCBI Official Synonym Full Names
apolipoprotein B mRNA editing enzyme catalytic subunit 1
NCBI Official Symbol
APOBEC1
NCBI Official Synonym Symbols
BEDP; HEPR; CDAR1; APOBEC-1
UniProt Protein Name
C->U-editing enzyme APOBEC-1
UniProt Synonym Protein Names
Apolipoprotein B mRNA-editing enzyme 1; HEPR
Protein Family
UniProt Gene Name
APOBEC1
UniProt Entry Name
ABEC1_HUMAN
NCBI Protein Information
C->U-editing enzyme APOBEC-1

UniProt Comments for APOBEC1

Function: Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Ref.8

Cofactor: Zinc

By similarity.

Subunit structure: Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Found in a complex with CELF2/CUGBP2 and A1CF. Interacts with HNRPAB and SYNCRIP. Ref.6 Ref.7

Subcellular location: Cytoplasm Ref.9.

Tissue specificity: Expressed exclusively in the small intestine.

Sequence similarities: Belongs to the cytidine and deoxycytidylate deaminase family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-APOBEC1 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >8 publications with APOBEC1 and Intestine
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