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ABCC4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2563302

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ABCC4, Polyclonal Antibody
Full Product Name
ABCC4 Polyclonal Antibody
Product Gene Name
anti-ABCC4 antibody
Product Synonym Names
ABCC 4; ABCC4; ATP binding cassette sub family C (CFTR/MRP) member 4; ATP binding cassette sub family C member 4; ATP-binding cassette sub-family C member 4; BA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4); BA464I2.1; Canalicular multispecific organic anion transporter; Canalicular multispecific organic anion transporter ABC superfamily; EST170205; MOAT B; MOAT-B; MOATB; MRP 4; MRP/cMOAT related ABC transporter; MRP/cMOAT-related ABC transporter; MRP4; Multi specific organic anion transporter B; Multi-specific organic anion transporter B; Multidrug resistance associated protein 4; Multidrug resistance-associated protein 4; OTTHUMP00000018560
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.5mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
OMIM
605250
3D Structure
ModBase 3D Structure for O15439
Immunogen
Synthetic peptide of human ABCC4
Conjugation
Unconjugated

Product Categories/Family for anti-ABCC4 antibody

Cancer; Metabolism; Signal Transduction
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ABCC4 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-ABCC4 antibody
IHC: 1:25-1:100
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-ABCC4 antibody

Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ABCC4 Polyclonal Antibody at dilution of 1:30(×200)
Rabbit Anti-ABCC4 Polyclonal Antibody – Cat# MBS2563302

Other Notes

Small volumes of anti-ABCC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABCC4 purchase

MBS2563302 is an antibody targeting ABCC4. Also known as ABCC4 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCC4. It may not necessarily be applicable to this product.

NCBI GI #
206729914
NCBI GeneID
10257
NCBI Accession #
O15439.3
UniProt Primary Accession #
O15439
UniProt Related Accession #
O15439
NCBI Official Full Name
Multidrug resistance-associated protein 4
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 4
NCBI Official Symbol
ABCC4
NCBI Official Synonym Symbols
MRP4; MOATB; MOAT-B
UniProt Protein Name
Multidrug resistance-associated protein 4
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B
Protein Family
ABC transporter C family
UniProt Gene Name
ABCC4
UniProt Synonym Gene Names
MRP4; MOAT-B
UniProt Entry Name
MRP4_HUMAN
NCBI Protein Information
multidrug resistance-associated protein 4

UniProt Comments for ABCC4

ABCC4: a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

Protein type: Transporter; Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q32

Cellular Component: membrane; basolateral plasma membrane; integral to membrane; plasma membrane; platelet dense granule membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; 15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding

Biological Process: response to drug; platelet activation; platelet degranulation; positive regulation of smooth muscle cell proliferation; response to organic nitrogen; blood coagulation; transmembrane transport; response to organic cyclic substance
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Research Articles on ABCC4

1. Inhibition of ABCC4 potentiates combination beta agonist and glucocorticoid responses in human airway epithelial cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ABCC4 antibody

 Reference Product  PubMed Publications
 SLC22A8 antibody  >9 publications with ABCC4 and SLC22A8
 SLC22A6 antibody  >8 publications with ABCC4 and SLC22A6
 SLCO1B3 antibody  >7 publications with ABCC4 and SLCO1B3
 SLCO1B1 antibody  >7 publications with ABCC4 and SLCO1B1
 SNX27 antibody  >1 publications with ABCC4 and SNX27

Pathways associated with anti-ABCC4 antibody

 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Drug Induction Of Bile Acid Pathway antibodies  Drug Induction Of Bile Acid Pathway Diagram
 Fluoropyrimidine Activity Pathway antibodies  Fluoropyrimidine Activity Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram

Diseases associated with anti-ABCC4 antibody

 Disease Name  Pubmed Publications
 Cholestasis Antibodies  >21 publications with ABCC4 and Cholestasis
 Inflammation Antibodies  >18 publications with ABCC4 and Inflammation
 Liver Diseases Antibodies  >18 publications with ABCC4 and Liver Diseases
 Adenocarcinoma Antibodies  >13 publications with ABCC4 and Adenocarcinoma
 Disease Models, Animal Antibodies  >13 publications with ABCC4 and Disease Models, Animal
 Necrosis Antibodies  >11 publications with ABCC4 and Necrosis
 Fibrosis Antibodies  >11 publications with ABCC4 and Fibrosis
 Brain Diseases Antibodies  >10 publications with ABCC4 and Brain Diseases
 Colorectal Neoplasms Antibodies  >10 publications with ABCC4 and Colorectal Neoplasms
 Neoplasms, Experimental Antibodies  >9 publications with ABCC4 and Neoplasms, Experimental

Organs/Tissues associated with anti-ABCC4 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >111 publications with ABCC4 and Blood
 Liver Antibodies  >78 publications with ABCC4 and Liver
 Kidney Antibodies  >74 publications with ABCC4 and Kidney
 Brain Antibodies  >47 publications with ABCC4 and Brain
 Lung Antibodies  >21 publications with ABCC4 and Lung
 Vascular Antibodies  >21 publications with ABCC4 and Vascular
 Intestine Antibodies  >19 publications with ABCC4 and Intestine
 Muscle Antibodies  >13 publications with ABCC4 and Muscle
 Prostate Antibodies  >9 publications with ABCC4 and Prostate
 Bone Antibodies  >8 publications with ABCC4 and Bone
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