8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate (8-pCPT-cGMP), fluorescence grade

C₁₆H₁₄ClN₅O₇PS.Na; MW 509.8; lambda_max 276 nm; epsilon 21500; sodium salt, purity > 99% HPLC; specially purified quality, fluorescent impurities removed. For other salt forms please inquire. Selective activator of both, cGMP-dependent protein kinase type I alpha and type II, as well as of cGMP-gated ion channels. Higher activation potential compared to cGMP; excellent cell membrane permeability and stability towards many phosphodiesterases. Recommendable alternative to unsuitable analogues such as dibutyryl cGMP. Detailed technical information and updated reference list available on request. Reference: Geiger et al., Proc. Natl. Acad. Sci. USA, 89, 1031 - 1035 (1992).

Small volumes of 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate (8-pCPT-cGMP) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS256424 is a biochemical targeting 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate (8-pCPT-cGMP). Also known as 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate (8-pCPT-cGMP), fluorescence grade.