Cyclic diadenosine monophosphate (c-diAMP / c-di-AMP / cyclic bis (3' -> 5') diadenylic acid)

C₂₀H₂₄N₁₀O₁₂P₂; MW 658.4 (free acid); lambda_max 259 nm; epsilon 27000; sodium salt; purity > 98% HPLC (typically > 99%). For other salt forms please inquire.

c-diAMP was identified as a second messenger that signals DNA integrity in Bacillus subtilis during sporulation, and is considered to be an additional purine-based signalling nucleotide with a more general function in prokaryotes. Detailed technical information available. The structurally related bacterial second messenger c-diGMP is offered as well. References: Simm et al., J. Bacteriol., 189, 3613 - 3623 (2007); Witte et al., Mol. Cell, 30, 167 - 178 (2008); Oppenheimer-Shaanan et al., EMBO Rep., 12, 594 - 601 (2011).

Small volumes of Cyclic diadenosine monophosphate (c-diAMP / c-di-AMP / cyclic bis (3' -> 5') diadenylic acid) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS256456 is a biochemical targeting Cyclic diadenosine monophosphate (c-diAMP / c-di-AMP / cyclic bis (3' -> 5') diadenylic acid).