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2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate (2'-Fluo-AHC-cAMP / FAM-cAMP)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS256460

2'-Fluo-AHC-cAMP is a fluorescein-modified analogue of the parent second messenger cyclic AMPinwhichthe dye is connected to the ribose 2'-hydroxy group via a 9-atom spacer More details

$600 / 1 umol +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate (2'-Fluo-AHC-cAMP / FAM-cAMP), Biochemical
Full Product Name
2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate (2'-Fluo-AHC-cAMP / FAM-cAMP)
Purity/Purification
Typical analysis is better than 95% (HPLC/UV/VIS/478nm). The product is not sterileand has not been tested for endotoxins.
Specificity
Lyophilized or crystallized sodium salt. Other salt forms are available upon request. Equal concentrations of 2'-Fluo-AHC-cAMPcan appear very different in volume due to sensitivity of the lyophilized form to humidity. The compound can even contract to small volume droplets. Normally the product is located in the conical bottom of the tube. Micromolar quantities are determined by UV/VIS at λmax.
Preparation and Storage
Fluo-AHC-cAMP is chemically rather stableand does not need special care during handling or shipment. Nevertheless, the compound should be protected from light and stored in the freezer, for longer storage periods preferably in freeze-dried form.
Molecular Weight
851.7
Properties
Fluorescent, PKA-inactive analogue of cyclic AMP with λexc 494nm and λ 517nm. 2'-Fluo-AHC-cAMPcan be used as a substrate inphosphodiesterase studies.
Solubility
2'-Fluo-AHC-cAMP is solubleto at least 1mM in water. In case higher concentrations are required it could be advisable to add some DMSO or methanol to increase solubility. Please rinse tube walls carefully and preferably use ultrasonic or vortex to achieve total and uniform mixing. When opening the tube please make sure that no substance is lost within the cap.
UV
λmax ~494 nm ε ~79000/ pH9
Formula
C38H35N7O13P.Na

Other Notes

Small volumes of 2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate (2'-Fluo-AHC-cAMP / FAM-cAMP) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS256460 is a biochemical targeting 2'- (6- [ Fluoresceinyl]aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphate (2'-Fluo-AHC-cAMP / FAM-cAMP).
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