Adenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester (cAMP-AM)

C₁₃H₁₆N₅O₈P; MW 401.3; lambda_max 259 nm; epsilon 15000. Purity > 97% HPLC for mixture isomers. Highly membrane-permeant precursor of the second messenger cyclic AMP. After permeation and metabolic activation by esterases the polar cAMP is released which is trapped inside the cell and subsequently metabolized quickly, resulting in a pulse-type signal. Detailed technical information and updated reference list available. Reference: Schultz et al., J. Biol. Chem., 268, 6316 - 6322 (1993).

Biolog also offers Phosphate tris(acetoxymethyl)ester which is recommended as control reagent in nucleotide-AM ester applications.

Small volumes of Adenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester (cAMP-AM) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS256461 is a biochemical targeting Adenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester (cAMP-AM).