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CSNK1A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2565562

CSNK1A1 (Casein Kinase 1 Alpha 1) is a Protein Coding gene. Diseases associated with CSNK1A1 include Enterobiasis and Gastric Cancer. Among its related pathways are Signaling by GPCR and S45 mutants of beta-catenin arent phosphorylated. Gene Ontology (GO)… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CSNK1A1, Polyclonal Antibody
Full Product Name
CSNK1A1 Polyclonal Antibody
Product Gene Name
anti-CSNK1A1 antibody
Product Synonym Names
CSNK1A1; CK1; CK1a; CKIa; HEL-S-77p; HLCDGP1; PRO2975
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purity/Purification
Affinity purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
38,915 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (148874845..148931007, complement). Location: 5q32
OMIM
600505
3D Structure
ModBase 3D Structure for P48729
Immunogen
A synthetic peptide of human CSNK1A1 (NP_0010202761)
Conjugation
Unconjugated

Product Categories/Family for anti-CSNK1A1 antibody

Cancer; Signal Transduction; Stem Cells; Polyclonal Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CSNK1A1 antibody
Immunohistochemistry (IHC)
Application Notes for anti-CSNK1A1 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-CSNK1A1 antibody

Immunohistochemistry of paraffin-embedded Human tonsil using CSNK1A1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-CSNK1A1 Polyclonal Antibody – Cat# MBS2565562

Immunohistochemistry (IHC) of anti-CSNK1A1 antibody

Immunohistochemistry of paraffin-embedded Human placenta using CSNK1A1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-CSNK1A1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2565562

Other Notes

Small volumes of anti-CSNK1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSNK1A1 purchase

MBS2565562 is an antibody targeting CSNK1A1. Also known as CSNK1A1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CSNK1A1. It may not necessarily be applicable to this product.

NCBI GI #
68303575
NCBI GeneID
1452
NCBI Accession #
NP_001020276.1
UniProt Primary Accession #
P48729
UniProt Secondary Accession #
Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q96HD2; Q9UDK3; D3DQG0; D3DQG1
UniProt Related Accession #
P48729
GenBank Nucleotide #
NM_001025105.2
NCBI Official Full Name
casein kinase I isoform alpha isoform 1
NCBI Official Synonym Full Names
casein kinase 1 alpha 1
NCBI Official Symbol
CSNK1A1
NCBI Official Synonym Symbols
CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p
UniProt Protein Name
Casein kinase I isoform alpha
UniProt Synonym Protein Names
CK1
Protein Family
Casein kinase
UniProt Gene Name
CSNK1A1
UniProt Synonym Gene Names
CKI-alpha
UniProt Entry Name
KC1A_HUMAN
NCBI Protein Information
casein kinase I isoform alpha

UniProt Comments for CSNK1A1

CK1A: an ubiquitous protein kinase of the CK1 family. Participates in Wnt signaling. Phosphorylates beta catenin, marking it for beta-TRCp-mediated ubiquitinylation and proteasomal degradation.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CK1; EC 2.7.11.1; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: centrosome; membrane; cytoplasm; nuclear speck; mRNA cleavage and polyadenylation specificity factor complex; cytosol

Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase activity

Biological Process: mitosis; regulation of cell shape; peptidyl-serine phosphorylation; cell surface receptor linked signal transduction; Wnt receptor signaling pathway; cell division; signal transduction; protein amino acid phosphorylation; phagocytosis
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Research Articles on CSNK1A1

1. Interactome analyses revealed that the Jade-1S mutant unable to be phosphorylated by CK1alpha has an increased binding affinity to proteins involved in chromatin remodelling, histone deacetylation, transcriptional repression, and ribosome biogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CSNK1A1 antibody

 Reference Product  PubMed Publications
 CTNNB1 antibody  >3 publications with CSNK1A1 and CTNNB1
 TP53 antibody  >1 publications with CSNK1A1 and TP53

Pathways associated with anti-CSNK1A1 antibody

 Products by Pathway  Pathway Diagram
 Beta-catenin Phosphorylation Cascade Pathway antibodies  Beta-catenin Phosphorylation Cascade Pathway Diagram
 Canonical Wnt Signaling Pathway antibodies  Canonical Wnt Signaling Pathway Diagram
 Degradation Of Beta-catenin By The Destruction Complex Pathway antibodies  Degradation Of Beta-catenin By The Destruction Complex Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Noncanonical Wnt Signaling Pathway antibodies  Noncanonical Wnt Signaling Pathway Diagram
 Presenilin Action In Notch And Wnt Signaling Pathway antibodies  Presenilin Action In Notch And Wnt Signaling Pathway Diagram
 Role Of Calcineurin-dependent NFAT Signaling In Lymphocytes Pathway antibodies  Role Of Calcineurin-dependent NFAT Signaling In Lymphocytes Pathway Diagram

Diseases associated with anti-CSNK1A1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with CSNK1A1 and Neoplasms
 Breast Neoplasms Antibodies  >1 publications with CSNK1A1 and Breast Neoplasms
 Anemia Antibodies  >1 publications with CSNK1A1 and Anemia
 Cell Transformation, Neoplastic Antibodies  >1 publications with CSNK1A1 and Cell Transformation, Neoplastic
 Drug Toxicity Antibodies  >1 publications with CSNK1A1 and Drug Toxicity

Organs/Tissues associated with anti-CSNK1A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with CSNK1A1 and Lung
 Lymph Node Antibodies  >1 publications with CSNK1A1 and Lymph Node
 Intestine Antibodies  >1 publications with CSNK1A1 and Intestine
 Brain Antibodies  >1 publications with CSNK1A1 and Brain
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