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β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS256558

ara-2'-F-NAD+ is an analogue of β-NAD+ in which the nicotinamide-connected ribose is replaced by 2'-fluoro arabinose More details

$925 / 0.1 umol +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+), Biochemical
Full Product Name
β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+)
Product Synonym Names
β-araF-NAD+ / β-2'-Fluoro-ara-NAD+ / 2'-Fluoro-2'-deoxy-substituted nicotinamide arabinoside adenine dinucleotide
Purity/Purification
Typical analysis is better than 97% (HPLC / UV / 260 nm). The product is not sterile and has not been tested for endotoxins.
Specificity
Lyophilized or crystallized sodium salt. The free acid or other salt forms are available upon request. Equal concentrations of ara-2'-F-NAD+ can appear very different in volume due to sensitivity of the lyophilized form to humidity. The compound can even contract to small volume droplets. Normally the product is located in the conical bottom of the tube. Micromolar quantities are determined by UV at λmax.
Preparation and Storage
ara-2'-F-NAD+ aliquots (freeze-dried or in solution) are sufficiently stable to be stored up to 7 days at room temperature. Nevertheless, we recommend that the compound should be stored in the freezer, for longer storage periods preferably in freeze-dried form (-20 degrees Celsius necessary, -80 degrees Celsius recommended).
Molecular Weight
665.4 (free acid)
CAS No.
133575-27-6
Formula
C21H26FN7O13P2
UV
λmax 260nm/ ε 20000/pH7
Properties
ara-2'-F-NAD+ is a hydrolysis-resistant slow binding inhibitor of ADP-ribosyl cyclase (i.e. CD 38).
Solubility
ara-2'-F-NAD+ has excellent solubility in water and aqueous buffers (> 30 mM, limits have not been determined). Please rinse tube walls carefully and preferably use ultrasonic or vortex to achieve total and uniform mixing. When opening the tube please make sure that no substance is lost within the cap.
Toxicity and Safety
Please keep in mind that the in vivo properties of this compound are not sufficiently characterized up to now. Avoid skin contact or ingestion and allow only trained personnel to handle the product. Our products are designed, developed and sold for research purposes only. They are intended for in vitro and nonhuman in vivo laboratory applications. Any other use requires approval of health authorities. Not for drug, household or related uses.

Structure of β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+) biochemical

β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+) Biochemical – Cat# MBS256558

Other Notes

Small volumes of β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+) purchase

MBS256558 is a biochemical targeting β- ara- 2'- Deoxy- 2'- fluoro- nicotinamide adenine dinucleotide (ara-2'-F-NAD+).
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