2'- Deoxy- 2'- fluoroadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-2'-F-dATP-alpha-S), sodium salt

Tetrasodium. Aqueous solution of the sodium salt (10 mM).

Typical purity is >95% (HPLC/ UV/ 259 nm) at time of quality control and packing. However, actual purity depends on storage and transport conditions. The product is not sterile and has not been tested for endotoxins

Store at -70 degree C
It is relatively stable when stored as aqueous solution in the freezer (-20 degree Celsius necessary, -80 degree recommended), however, at ambient temperature the compound slowly starts to decompose forming 2'-deoxy-2'-fluoro-ATP (2'-F-dATP) and other nucleotide fragments. Thus, in order to maintain its original high quality, and especially if you want to avoid the presence of any 2'-F-dATP, it is recommended to allow thawing only before using the product. If you will not use up the vial with one application, please aliquot the contents of the vial in order to avoid repeated freeze/thaw cycles for the rest. When making such aliquots be sure to operate quickly and to freeze the vial again as soon as possible.
Shipping: Dry Ice

525.24

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• Increased metabolic stability compared to the parent compounds 2'-F-dATP and dATP, respectively,
• Useful for modulation of dATP-responsive receptors and determination of their stereospecificity
• May be accepted by DNA polymerases for incorporation of phosphorothioate into DNA.

lambda max 259 nm, epsilon 15200, pH 7

Micromolar quantities are determined by UV at lambda max. When opening the tube please make sure that no liquid is lost within the cap. A short spin-down in a bench centrifuge is recommended before use.
Since dATP has important tasks in every organism, it is very likely that dATP analogues will interfere with manycell regulation processes in vivo. However, due to the rather small quantities to work with, no health hazards have been reported.

Extra charge fee may add to your shipping cost as dry ice is required to ship this product.