P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A/ epsilon-Apppp-epsilon-A), sodium salt Biochemical – Cat# MBS256653

P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A/ epsilon-Apppp-epsilon-A), sodium salt (P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- Ethenoadenosyl])- Tetraphosphate (Epsilon-Ap-Epsilon-A / Epsilon-Apppp-Epsilon-A))

Name: P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- Ethenoadenosyl])- Tetraphosphate (Epsilon-Ap-Epsilon-A / Epsilon-Apppp-Epsilon-A); MyBioSource
Brand: MyBioSource
SKU: MBS256653
Price: 820 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS256653

Fluorescent analogue of Ap4A. epsilon-Ap?-epsilon-A is a fluorescent modification of the naturally occurring dinucleoside polyphosphate Ap4A, where twoadenosine moieties are linked via their 5' positions by four phosphate groups. Both adenine nucleobases are… More details

$820 / 1 umol +1 FREE 8GB USB

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Product Overview

Online Datasheet in PDF

Product Name

P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A), Biochemical

Full Product Name

P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A/ epsilon-Apppp-epsilon-A), sodium salt

Product Synonym Names

P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate

Form/Format

Tetrasodium. Lyophilized or crystallized sodium salt.

Purity/Purification

Typical analysis is >95% (HPLC/ UV/ 275 nm). The product is not sterile and has not been tested for endotoxins.

Preparation and Storage

Store at -20 degree C
Protect from light.
It has sufficient stability at room temperature and does not need special care during handling orshipment. Nevertheless, we recommend that the compound should be protected from light, stored in the freezer, for longer storage periods preferably in freeze-dried form.

Molecular Weight

884.44

Solubility

epsilon-Ap?-epsilon-A has good solubility in water and aqueous buffers (>= 10 mM, limits have not been determined).

SMILES

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN4C3=NC=C4)O[C@@H]1COP(OP(OP(OP(OC[C@H]5O[C@@H](N6C=NC7=C6N=CN8C7=NC=C8)[C@H](O)[C@@H]5O)([O-])=O)([O-])=O)([O-])=O)([O-])=O.[Na+].[Na+].[Na+].[Na+]

CAS Number

96920-51-3

Formula

C??H??N??O??P?

Properties

The etheno groups of epsilon-Ap?-epsilon-A fluoresce with exc 307 nm and em 410 nm.

lambda max 275 nm, epsilon 10800, pH 7

Notes

Equal concentrations of epsilon-Ap?-epsilon-A can appear very different in volume due to sensitivity of the lyophilized form to humidity. The compound can even contract to small volume droplets. Normally the product is located in the conical bottom of the tube. Micromolar quantities are determined by UV at lambda max.
Please rinse tube walls carefully and preferably use ultrasonic or vortex to achieve total and uniform mixing.
Please keep in mind that the in vivo properties of this compound are not sufficiently characterized up to now.

Product References and Citations for P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A) biochemical

Rotilan, P.; Ramos, A.; Pintor, J.; Tortes, M.; Mires-Portugal, M.T., FEBS Lett., 280, 371 - 374 (1991): "Di(1,N6-ethenoadenosine)5',5"'-P1,P4-tetraphosphate, a fluorescent enzymatically active derivative of Ap4A"
Gasmi, L.; Cartwright, J.L.; McLennan, A.G., Biochim. Biophys. Acta, 1405, 121 - 127 (1998): "The hydrolytic activity of bovineadrenal medullary plasma membranes towards diadenosine polyphosphates is due to alkaline phosphodiesterase-I".

Other Notes

Small volumes of P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A) purchase

MBS256653 is a biochemical targeting P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A). Also known as P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A/ epsilon-Apppp-epsilon-A), sodium salt.

P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A/ epsilon-Apppp-epsilon-A), sodium salt (P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- Ethenoadenosyl])- Tetraphosphate (Epsilon-Ap-Epsilon-A / Epsilon-Apppp-Epsilon-A))

Product Overview

Structure of P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A) biochemical

Related Product Information for P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A) biochemical

Product References and Citations for P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A) biochemical

Other Notes

Searchable Terms for P1- (5'- [1, N6- Ethenoadenosyl])- P4- (5'- [1, N6- ethenoadenosyl])- tetraphosphate (epsilon-Ap-epsilon-A / epsilon-Apppp-epsilon-A) purchase