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CFP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2575338

This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CFP, Polyclonal Antibody
Full Product Name
CFP Polyclonal Antibody
Product Gene Name
anti-CFP antibody
Product Synonym Names
CFP; BFD; PFC; PFD; PROPERDIN; properdin
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Purity/Purification
Affinity purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
Molecular Weight
51,276 Da
OMIM
300383
3D Structure
ModBase 3D Structure for P27918
Immunogen
Recombinant fusion protein of human CFP

Product Categories/Family for anti-CFP antibody

Antibodies; Primary Antibodies; Polyclonal Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CFP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CFP antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200

Western Blot (WB) of anti-CFP antibody

Western blot analysis of extracts of mouse spleen using CFP Polyclonal Antibody at 1:1000 dilution.
Rabbit Anti-CFP Polyclonal Antibody – Cat# MBS2575338

Western Blot (WB) of anti-CFP antibody

Western blot analysis of extracts of Jurkat cells using CFP Polyclonal Antibody at 1:1000 dilution.
Rabbit Anti-CFP Polyclonal Antibody, Western Blot (WB) – Cat# MBS2575338

Immunohistochemistry (IHC) of anti-CFP antibody

Immunohistochemistry of paraffin-embedded human colon carcinoma using CFP Polyclonal Antibody at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Rabbit Anti-CFP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2575338

Immunofluorescence (IF) of anti-CFP antibody

Immunofluorescence analysis of NIH-3T3 cells using CFP Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-CFP Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS2575338

Immunofluorescence (IF) of anti-CFP antibody

Immunofluorescence analysis of U2OS cells using CFP Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-CFP Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS2575338

Other Notes

Small volumes of anti-CFP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CFP purchase

MBS2575338 is an antibody targeting CFP. Also known as CFP Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CFP. It may not necessarily be applicable to this product.

NCBI GI #
355757320
NCBI GeneID
0
NCBI Accession #
EHH60845.1
UniProt Primary Accession #
P27918
UniProt Secondary Accession #
O15134; O15135; O15136; O75826
NCBI Official Full Name
Complement factor P
UniProt Protein Name
Properdin
UniProt Synonym Protein Names
Complement factor P
Protein Family
Properdin
UniProt Gene Name
CFP
UniProt Synonym Gene Names
PFC
UniProt Entry Name
PROP_HUMAN

UniProt Comments for CFP

CFP: A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: Xp11.4

Cellular Component: extracellular matrix; extracellular space; endoplasmic reticulum lumen; extracellular region

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; defense response to bacterium; complement activation, alternative pathway; regulation of complement activation; innate immune response; immune response; post-translational protein modification; complement activation

Disease: Properdin Deficiency, X-linked
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CFP antibody

 Reference Product  PubMed Publications
 CFB antibody  >3 publications with CFP and CFB

Diseases associated with anti-CFP antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >440 publications with CFP and Neoplasms
 Hypertension Antibodies  >181 publications with CFP and Hypertension
 Breast Neoplasms Antibodies  >96 publications with CFP and Breast Neoplasms
 Necrosis Antibodies  >67 publications with CFP and Necrosis
 Inflammation Antibodies  >57 publications with CFP and Inflammation
 Drug Toxicity Antibodies  >55 publications with CFP and Drug Toxicity
 Weight Loss Antibodies  >50 publications with CFP and Weight Loss
 Prostatic Diseases Antibodies  >49 publications with CFP and Prostatic Diseases
 Disease Models, Animal Antibodies  >37 publications with CFP and Disease Models, Animal
 Abnormalities, Drug-Induced Antibodies  >36 publications with CFP and Abnormalities, Drug-Induced

Organs/Tissues associated with anti-CFP antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >769 publications with CFP and Blood
 Lung Antibodies  >149 publications with CFP and Lung
 Brain Antibodies  >138 publications with CFP and Brain
 Bone Antibodies  >137 publications with CFP and Bone
 Muscle Antibodies  >123 publications with CFP and Muscle
 Vascular Antibodies  >90 publications with CFP and Vascular
 Liver Antibodies  >58 publications with CFP and Liver
 Spleen Antibodies  >26 publications with CFP and Spleen
 Bone Marrow Antibodies  >23 publications with CFP and Bone Marrow
 Connective Tissue Antibodies  >20 publications with CFP and Connective Tissue
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