• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PSMA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2579136

Prostate-specific membrane antigen (PSMA) is expressed in normal and malignant prostatic epithelium and in a subset of non-prostatic tissues. In prostate cancer, PSMA expression has been shown to correlate with disease progression, with highest levels… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
PSMA, Polyclonal Antibody
Full Product Name
PSMA Polyclonal Antibody
Product Gene Name
anti-PSMA antibody
Product Synonym Names
Glutamate carboxypeptidase 2; Folate hydrolase 1; Folylpoly-gamma-glutamate; carboxypeptidase (FGCP); Glutamate carboxypeptidase II (GCPII); Membrane glutamate carboxypeptidase (mGCP); N-acetylated-alpha-linked acidic dipeptidase I (NAALADase I); Prostate-specific membrane antigen homolog; Pteroylpoly-gamma-glutamate; carboxypeptidase; PSMA; Mopsm; Naalad1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.
Molecular Weight
84,574 Da
3D Structure
ModBase 3D Structure for O35409
Immunogen
Recombinant Mouse PSMA Protein expressed by E coli

Product Categories/Family for anti-PSMA antibody

Polyclonal Antibodies; Primary Antibodies; Polyclonal Antibodies; Signal Transduction; Cancer; Metabolism
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PSMA antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PSMA antibody
WB: 1:500-1:1000
IHC: 1:100-1:300

Western Blot (WB) of anti-PSMA antibody

Western blot with PSMA Polyclonal Antibody at dilution of 1:1000.lane 1:LNCaP whole cell lysate
Rabbit Anti-PSMA Polyclonal Antibody – Cat# MBS2579136

Immunohistochemistry (IHC) of anti-PSMA antibody

Immunohistochemistry of paraffin-embedded Human prostate cancer using PSMA Polycloanl Antibody at dilution of 1:200
Rabbit Anti-PSMA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579136

Immunohistochemistry (IHC) of anti-PSMA antibody

Immunohistochemistry of paraffin-embedded Human kidney cancer using PSMA Polycloanl Antibody at dilution of 1:200
Rabbit Anti-PSMA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579136

Immunohistochemistry (IHC) of anti-PSMA antibody

Immunohistochemistry of paraffin-embedded Mouse brain using PSMA Polycloanl Antibody at dilution of 1:200
Rabbit Anti-PSMA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579136

Immunohistochemistry (IHC) of anti-PSMA antibody

Immunohistochemistry of paraffin-embedded Mouse kidney using PSMA Polycloanl Antibody at dilution of 1:200
Rabbit Anti-PSMA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579136

Immunohistochemistry (IHC) of anti-PSMA antibody

Immunohistochemistry of paraffin-embedded Rat brain using PSMA Polycloanl Antibody at dilution of 1:200
Rabbit Anti-PSMA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579136

Immunohistochemistry (IHC) of anti-PSMA antibody

Immunohistochemistry of paraffin-embedded Rat kidney using PSMA Polycloanl Antibody at dilution of 1:200
Rabbit Anti-PSMA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579136

Other Notes

Small volumes of anti-PSMA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMA purchase

MBS2579136 is an antibody targeting PSMA. Also known as PSMA Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMA. It may not necessarily be applicable to this product.

NCBI GI #
228008369
NCBI GeneID
53320
NCBI Accession #
NP_001153178.1
UniProt Primary Accession #
O35409
UniProt Secondary Accession #
Q0VDM5; Q9DCC2
UniProt Related Accession #
O35409
GenBank Nucleotide #
NM_001159706.1
NCBI Official Full Name
glutamate carboxypeptidase 2 isoform 2
NCBI Official Synonym Full Names
folate hydrolase 1
NCBI Official Symbol
Folh1
NCBI Official Synonym Symbols
GCP2; mopsm
UniProt Protein Name
Glutamate carboxypeptidase 2
UniProt Synonym Protein Names
Folate hydrolase 1; Folylpoly-gamma-glutamate carboxypeptidase; FGCP; Glutamate carboxypeptidase II; GCPII; Membrane glutamate carboxypeptidase; mGCP; N-acetylated-alpha-linked acidic dipeptidase I; NAALADase I; Prostate-specific membrane antigen homolog; Pteroylpoly-gamma-glutamate carboxypeptidase
UniProt Gene Name
Folh1
UniProt Synonym Gene Names
Mopsm; Naalad1; FGCP; GCPII; mGCP; NAALADase I
NCBI Protein Information
glutamate carboxypeptidase 2

UniProt Comments for PSMA

FOLH1: Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Belongs to the peptidase M28 family. M28B subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.17.21; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 7|7 D3

Cellular Component: integral to membrane; integral to plasma membrane

Molecular Function: carboxypeptidase activity; dipeptidase activity; peptidase activity

Biological Process: folic acid and derivative metabolic process; positive regulation of apoptosis; proteolysis
Show more

Research Articles on PSMA

1. Data support the hypothesis that the neuroprotective efficacy of glutamate carboxypeptidase II knockout in traumatic brain injury is mediated via a reduction in oxidative stress.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PSMA antibody

 Products by Pathway  Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 One Carbon Metabolism Pathway antibodies  One Carbon Metabolism Pathway Diagram
 Vitamin Digestion And Absorption Pathway antibodies  Vitamin Digestion And Absorption Pathway Diagram
 Vitamin Digestion And Absorption Pathway antibodies  Vitamin Digestion And Absorption Pathway Diagram
 Glutamate Removal From Folates Pathway antibodies  Glutamate Removal From Folates Pathway Diagram
 Glutathione-mediated Detoxification Pathway antibodies  Glutathione-mediated Detoxification Pathway Diagram

Diseases associated with anti-PSMA antibody

 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >9 publications with PSMA and Prostatic Neoplasms
 Brain Diseases Antibodies  >3 publications with PSMA and Brain Diseases
 Heart Diseases Antibodies  >2 publications with PSMA and Heart Diseases
 Nervous System Diseases Antibodies  >2 publications with PSMA and Nervous System Diseases
 Death Antibodies  >2 publications with PSMA and Death
 Lung Neoplasms Antibodies  >2 publications with PSMA and Lung Neoplasms
 Necrosis Antibodies  >2 publications with PSMA and Necrosis
 Musculoskeletal Diseases Antibodies  >1 publications with PSMA and Musculoskeletal Diseases
 Nerve Degeneration Antibodies  >1 publications with PSMA and Nerve Degeneration
 Hypertension Antibodies  >1 publications with PSMA and Hypertension

Organs/Tissues associated with anti-PSMA antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10 publications with PSMA and Blood
 Brain Antibodies  >7 publications with PSMA and Brain
 Kidney Antibodies  >4 publications with PSMA and Kidney
 Eye Antibodies  >2 publications with PSMA and Eye
 Liver Antibodies  >1 publications with PSMA and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000