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TRAF5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2579141

The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TRAF5, Polyclonal Antibody
Full Product Name
TRAF5 Polyclonal Antibody
Product Gene Name
anti-TRAF5 antibody
Product Synonym Names
RING finger protein 84; RNF 84; RNF84; TNF receptor associated factor 5; TNF receptor-associated factor 5; TRAF 5; Traf5; TRAF5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.
Molecular Weight
557
OMIM
602356
3D Structure
ModBase 3D Structure for O00463
Immunogen
Recombinant Human TRAF5 RNF84 Protein expressed by E coli

Product Categories/Family for anti-TRAF5 antibody

Polyclonal Antibodies; Primary Antibodies; Polyclonal Antibodies; Immunology
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TRAF5 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TRAF5 antibody
WB: 1:250-1:500
IHC: 1:100-1:400

Western Blot (WB) of anti-TRAF5 antibody

Western blot with TRAF5 Polyclonal Antibody at dilution of 1:500.lane 1:Jurkat whole cell lysate,lane 2:Hela whole cell lysate
Rabbit Anti-TRAF5 Polyclonal Antibody – Cat# MBS2579141

Immunohistochemistry (IHC) of anti-TRAF5 antibody

Immunohistochemistry of paraffin-embedded Human lymph node using TRAF5 Polyclonal Antibody at dilution of 1:200
Rabbit Anti-TRAF5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579141

Immunohistochemistry (IHC) of anti-TRAF5 antibody

Immunohistochemistry of paraffin-embedded Mouse kidney using TRAF5 Polyclonal Antibody at dilution of 1:200
Rabbit Anti-TRAF5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579141

Other Notes

Small volumes of anti-TRAF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRAF5 purchase

MBS2579141 is an antibody targeting TRAF5. Also known as TRAF5 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAF5. It may not necessarily be applicable to this product.

NCBI GI #
30580600
NCBI GeneID
7188
NCBI Accession #
O00463.2
UniProt Primary Accession #
O00463
UniProt Secondary Accession #
Q6FHY1; B4DIS9; B4E0A2
UniProt Related Accession #
O00463
NCBI Official Full Name
TNF receptor-associated factor 5
NCBI Official Synonym Full Names
TNF receptor-associated factor 5
NCBI Official Symbol
TRAF5
NCBI Official Synonym Symbols
RNF84; MGC:39780
UniProt Protein Name
TNF receptor-associated factor 5
UniProt Synonym Protein Names
RING finger protein 84
Protein Family
TNF receptor-associated factor
UniProt Gene Name
TRAF5
UniProt Synonym Gene Names
RNF84
UniProt Entry Name
TRAF5_HUMAN
NCBI Protein Information
TNF receptor-associated factor 5; RING finger protein 84

UniProt Comments for TRAF5

TRAF5: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Belongs to the TNF receptor-associated factor family. A subfamily.

Protein type: Adaptor/scaffold; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: centrosome; internal side of plasma membrane; cytoplasm; cytosol

Molecular Function: protein binding; signal transducer activity; zinc ion binding; thioesterase binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity

Biological Process: regulation of apoptosis; positive regulation of I-kappaB kinase/NF-kappaB cascade; apoptosis; positive regulation of cell proliferation; protein ubiquitination; positive regulation of transcription factor activity; signal transduction; activation of NF-kappaB transcription factor
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Research Articles on TRAF5

1. This study provides evidence that TRAF5 and TRAF3IP2 genes are involved in the development of Behcet's disease (BD) and Vogt-Koyanagi-Harada (VKH) syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRAF5 antibody

 Reference Product  PubMed Publications
 TRAF2 antibody  >108 publications with TRAF5 and TRAF2
 TRAF3 antibody  >63 publications with TRAF5 and TRAF3
 CD40 antibody  >39 publications with TRAF5 and CD40
 TNFRSF8 antibody  >10 publications with TRAF5 and TNFRSF8
 LTBR antibody  >8 publications with TRAF5 and LTBR
 TNFRSF11A antibody  >8 publications with TRAF5 and TNFRSF11A
 MAP3K5 antibody  >3 publications with TRAF5 and MAP3K5
 TNFRSF17 antibody  >2 publications with TRAF5 and TNFRSF17
 TNFRSF14 antibody  >2 publications with TRAF5 and TNFRSF14

Pathways associated with anti-TRAF5 antibody

 Products by Pathway  Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 RANKL/RANK Signaling Pathway antibodies  RANKL/RANK Signaling Pathway Diagram
 Small Cell Lung Cancer Pathway antibodies  Small Cell Lung Cancer Pathway Diagram
 Small Cell Lung Cancer Pathway antibodies  Small Cell Lung Cancer Pathway Diagram
 TNF Signaling Pathway antibodies  TNF Signaling Pathway Diagram

Diseases associated with anti-TRAF5 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >119 publications with TRAF5 and Necrosis
 Inflammation Antibodies  >21 publications with TRAF5 and Inflammation
 Nervous System Diseases Antibodies  >8 publications with TRAF5 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >8 publications with TRAF5 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >3 publications with TRAF5 and Atherosclerosis
 Neoplasms, Experimental Antibodies  >3 publications with TRAF5 and Neoplasms, Experimental
 Multiple Myeloma Antibodies  >2 publications with TRAF5 and Multiple Myeloma
 Uterine Cervical Neoplasms Antibodies  >1 publications with TRAF5 and Uterine Cervical Neoplasms
 Breast Neoplasms Antibodies  >1 publications with TRAF5 and Breast Neoplasms
 Kidney Diseases Antibodies  >1 publications with TRAF5 and Kidney Diseases

Organs/Tissues associated with anti-TRAF5 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >39 publications with TRAF5 and Blood
 Vascular Antibodies  >8 publications with TRAF5 and Vascular
 Lymph Node Antibodies  >8 publications with TRAF5 and Lymph Node
 Brain Antibodies  >5 publications with TRAF5 and Brain
 Intestine Antibodies  >5 publications with TRAF5 and Intestine
 Skin Antibodies  >5 publications with TRAF5 and Skin
 Kidney Antibodies  >5 publications with TRAF5 and Kidney
 Liver Antibodies  >5 publications with TRAF5 and Liver
 Lung Antibodies  >4 publications with TRAF5 and Lung
 Muscle Antibodies  >4 publications with TRAF5 and Muscle
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