Rabbit Anti-CHI3L1 Polyclonal Antibody – Cat# MBS2579185

Western blot with CHI3L1 Polyclonal antibody at dilution of 1:1000.lane 1:Mouse spleen,lane 2?Mouse lung

CHI3L1 Antibody – Rabbit Polyclonal

Name: CHI3L1 Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2579185
Price: 180 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2579185

Chitinase-3-like protein 1 (CHI3L1) also known as YKL-40, is a.secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CHI3L1, Polyclonal Antibody

Full Product Name

CHI3L1 Polyclonal Antibody

Product Gene Name

anti-CHI3L1 antibody

Product Synonym Names

Chitinase-3-like protein 1; BRP39 protein; Breast regression protein 39; Cartilage glycoprotein 39 (CGP-39; GP-39); Chi3l1; Brp39; Chil1; YKL40

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purity/Purification

Antigen Affinity Purification

Concentration

1mg/mL (lot specific)

Preparation and Storage

Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.

Molecular Weight

42,805 Da

3D Structure

ModBase 3D Structure for Q61362

Immunogen

Recombinant Mouse CHI3L1 protein expressed by E coli

Product Categories/Family for anti-CHI3L1 antibody

Polyclonal Antibodies; Primary Antibodies; Polyclonal Antibodies

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CHI3L1 antibody

Western Blot (WB)

Application Notes for anti-CHI3L1 antibody

WB: 1:500-1:1000

Other Notes

Small volumes of anti-CHI3L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHI3L1 purchase

MBS2579185 is an antibody targeting CHI3L1. Also known as CHI3L1 Polyclonal Antibody. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CHI3L1. It may not necessarily be applicable to this product.

NCBI GI #

635377452

NCBI GeneID

12654

NCBI Accession #

Q61362.3

UniProt Primary Accession #

Q61362

UniProt Secondary Accession #

Q3U291; Q4FJW9; Q8BKL8; Q99J84; B0FEU7; D3Z2P2

UniProt Related Accession #

Q61362

NCBI Official Full Name

Chitinase-3-like protein 1

NCBI Official Synonym Full Names

chitinase-like 1

NCBI Official Symbol

Chil1

NCBI Official Synonym Symbols

Gp39; Brp39; Chi3l1; AW208766

UniProt Protein Name

Chitinase-3-like protein 1

UniProt Synonym Protein Names

BRP39 protein; Breast regression protein 39; Cartilage glycoprotein 39; CGP-39; GP-39

Protein Family

Chitinase-3-like protein

UniProt Gene Name

Chi3l1

UniProt Synonym Gene Names

Brp39; Chil1; CGP-39; GP-39

UniProt Entry Name

CH3L1_MOUSE

NCBI Protein Information

chitinase-3-like protein 1; GP-39; CGP-39; chitinase 3-like 1; cartilage glycoprotein 39; breast regression protein 39

UniProt Comments for CHI3L1

CHI3L1: Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment. A genetic variation in CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea, bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis. Belongs to the glycosyl hydrolase 18 family.

Protein type: Secreted; Secreted, signal peptide; Cell adhesion

Cellular Component: extracellular space; endoplasmic reticulum; cytoplasm; extracellular region

Molecular Function: chitin binding; chitinase activity; hydrolase activity, hydrolyzing O-glycosyl compounds

Biological Process: positive regulation of protein kinase B signaling cascade; positive regulation of angiogenesis; apoptosis; carbohydrate metabolic process; activation of NF-kappaB-inducing kinase; immune response; chitin catabolic process; inflammatory response; lung development

Research Articles on CHI3L1

1. BRP-39 is involved in repressing the M1 proinflammatory phenotype in hyperoxia, thereby deactivating inflammatory responses in macrophages and preventing neonatal lung injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.