Rabbit Anti-SFTPD/SP-D Polyclonal Antibody – Cat# MBS2579191

Western blot with SFTPD/SP-D Polyclonal antibody at dilution of 1:1000.lane 1:Mouse lung,lane 2:Rat lung

SFTPD/SP-D Antibody – Rabbit Polyclonal

Name: SFTPD/SP-D Antibody; Polyclonal; Rabbit; Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2579191
Price: 180 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2579191

Pulmonary surfactant-associated protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Mouse SP-D cDNA encodes a 19 aa signal sequence and a 355 aa mature region with a 25 aa N-terminal linking-region, a 177 aa hydroxyproline… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SFTPD/SP-D, Polyclonal Antibody

Full Product Name

SFTPD/SP-D Polyclonal Antibody

Product Gene Name

anti-SFTPD/SP-D antibody

Product Synonym Names

Pulmonary surfactant-associated protein D; PSP-D; SP-D; Lung surfactant protein D; Sftpd; Sftp4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse, Rat

Form/Format

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purity/Purification

Antigen Affinity Purification

Concentration

1mg/mL (lot specific)

Preparation and Storage

Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.

Molecular Weight

37,688 Da

3D Structure

ModBase 3D Structure for P50404

Immunogen

Recombinant Mouse SFTPD/SP-D protein expressed by Mammalian

Product Categories/Family for anti-SFTPD/SP-D antibody

Polyclonal Antibodies; Primary Antibodies; Polyclonal Antibodies

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SFTPD/SP-D antibody

Western Blot (WB)

Application Notes for anti-SFTPD/SP-D antibody

WB: 1:500-1:1000

Other Notes

Small volumes of anti-SFTPD/SP-D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SFTPD/SP-D purchase

MBS2579191 is an antibody targeting SFTPD/SP-D. Also known as SFTPD/SP-D Polyclonal Antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SFTPD/SP-D. It may not necessarily be applicable to this product.

NCBI GI #

1709879

NCBI GeneID

20390

NCBI Accession #

P50404.1

UniProt Primary Accession #

P50404

UniProt Related Accession #

P50404

NCBI Official Full Name

Pulmonary surfactant-associated protein D

NCBI Official Synonym Full Names

surfactant associated protein D

NCBI Official Symbol

Sftpd

NCBI Official Synonym Symbols

SP-D; Sftp4; AI573415

UniProt Protein Name

Pulmonary surfactant-associated protein D

UniProt Synonym Protein Names

Lung surfactant protein D

UniProt Gene Name

Sftpd

UniProt Synonym Gene Names

Sftp4; PSP-D; SP-D

UniProt Entry Name

SFTPD_MOUSE

NCBI Protein Information

pulmonary surfactant-associated protein D; PSP-D; lung surfactant protein D

UniProt Comments for SFTPD/SP-D

SFTPD: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: multivesicular body; proteinaceous extracellular matrix; extracellular space; collagen; rough endoplasmic reticulum; cytoplasm; extracellular region; cytoplasmic vesicle

Molecular Function: monosaccharide binding; identical protein binding; lipopolysaccharide binding; carbohydrate binding

Biological Process: negative regulation of phagocytosis; negative regulation of T cell proliferation; immune system process; positive regulation of phagocytosis; innate immune response; opsonization; respiratory gaseous exchange; regulation of liquid surface tension; surfactant homeostasis; alveolus development; negative regulation of interleukin-2 production

Research Articles on SFTPD/SP-D

1. These results establish that DPPI is a major determinant of survival following Klebsiella pneumoniae lung infection and suggest that the survival disadvantage in DPPI(+/+) mice is in part due to processing of surfactant protein D by DPPI.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SFTPD/SP-D antibody

Reference Product	PubMed Publications
Sftpa1 antibody	>8 publications with SFTPD/SP-D and Sftpa1
Sftpb antibody	>7 publications with SFTPD/SP-D and Sftpb
Sftpc antibody	>5 publications with SFTPD/SP-D and Sftpc
Scgb1a1 antibody	>2 publications with SFTPD/SP-D and Scgb1a1
Slc34a2 antibody	>1 publications with SFTPD/SP-D and Slc34a2

Pathways associated with anti-SFTPD/SP-D antibody

Products by Pathway	Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram

Diseases associated with anti-SFTPD/SP-D antibody

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>23 publications with SFTPD/SP-D and Lung Diseases
Inflammation Antibodies	>15 publications with SFTPD/SP-D and Inflammation
Lung Injury Antibodies	>8 publications with SFTPD/SP-D and Lung Injury
Pneumonia Antibodies	>5 publications with SFTPD/SP-D and Pneumonia
Respiratory Hypersensitivity Antibodies	>3 publications with SFTPD/SP-D and Respiratory Hypersensitivity
Cardiovascular Diseases Antibodies	>3 publications with SFTPD/SP-D and Cardiovascular Diseases
Lung Neoplasms Antibodies	>3 publications with SFTPD/SP-D and Lung Neoplasms
Premature Birth Antibodies	>2 publications with SFTPD/SP-D and Premature Birth
Respiratory Distress Syndrome, Adult Antibodies	>2 publications with SFTPD/SP-D and Respiratory Distress Syndrome, Adult
Disease Models, Animal Antibodies	>2 publications with SFTPD/SP-D and Disease Models, Animal

Organs/Tissues associated with anti-SFTPD/SP-D antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>32 publications with SFTPD/SP-D and Lung
Embryonic Tissue Antibodies	>2 publications with SFTPD/SP-D and Embryonic Tissue