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CK-7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2579208

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the… More details

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Product Overview

Online Datasheet in PDF
Product Name
CK-7, Polyclonal Antibody
Full Product Name
CK-7 Polyclonal Antibody
Product Gene Name
Product Synonym Names
CK 7; CK-7; CK7; Cytokeratin 7; Cytokeratin-7; D15Wsu77e; K2C7; K2C7; K7; Keratin 7; Keratin 7; type II; Keratin type II cytoskeletal 7; Keratin; 55K type II cytoskeletal; Keratin; simple epithelial; Keratin; simple epithelial type I; K7; Keratin; type II cytoskeletal 7; Keratin-7; Krt2-7; KRT7; MGC11625; MGC129731; MGC3625; Sarcolectin; SCL; Type II mesothelial keratin K7; Type-II keratin Kb7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles.
Molecular Weight
51,386 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (52626954..52642709). Location: 12q13.13
OMIM
148059
3D Structure
ModBase 3D Structure for P08729
Immunogen
Recombinant Human CK-7 protein expressed by E coli
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CK-7 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CK-7 antibody
IHC: 1:500-1:1000
IF: 1:50-1:200

Immunohistochemistry (IHC) of anti-CK-7 antibody

Immunohistochemistry of paraffinembedded Human lung adenocarcinoma using CK-7 Polyclonal antibodyat dilution of 1:1000.
Rabbit Anti-CK-7 Polyclonal Antibody – Cat# MBS2579208

Immunohistochemistry (IHC) of anti-CK-7 antibody

Immunohistochemistry of paraffinembedded Human colon using CK-7 Polyclonal antibodyat dilution of 1:500.
Rabbit Anti-CK-7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579208

Immunohistochemistry (IHC) of anti-CK-7 antibody

Immunohistochemistry of paraffinembedded Human kidney using CK-7 Polyclonal antibodyat dilution of 1:500.
Rabbit Anti-CK-7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2579208

Immunofluorescence (IF) of anti-CK-7 antibody

Immunofluorescence analysis of Hela cells using CK-7 Polyclonal Antibody at dilution of 1:200
Rabbit Anti-CK-7 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS2579208

Other Notes

Small volumes of anti-CK-7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CK-7 purchase

MBS2579208 is an antibody targeting CK-7. Also known as CK-7 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CK-7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
keratin, type II cytoskeletal 7
NCBI Official Synonym Full Names
keratin 7
NCBI Official Symbol
KRT7
NCBI Official Synonym Symbols
K7; CK7; SCL; K2C7
UniProt Protein Name
Keratin, type II cytoskeletal 7
UniProt Synonym Protein Names
Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7
UniProt Gene Name
KRT7
UniProt Synonym Gene Names
SCL; CK-7; K7
UniProt Entry Name
K2C7_HUMAN
NCBI Protein Information
keratin, type II cytoskeletal 7; CK-7; keratin-7; sarcolectin; cytokeratin 7; cytokeratin-7; type-II keratin Kb7; type II mesothelial keratin K7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7

NCBI Summary for CK-7

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
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UniProt Comments for CK-7

K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytoplasm; keratin filament; intermediate filament; nucleus

Molecular Function: protein binding; structural molecule activity

Biological Process: viral reproduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CK-7 antibody

 Products by Pathway  Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
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