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APRIL Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS258221

Description: A proliferation-inducing ligand (APRIL), also known as TNFSF13, is a member of the tumor necrosis factor (TNF) ligand superfamily. APRIL/TNFSF13 has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell… More details

$360 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APRIL, Recombinant Protein
Full Product Name
Recombinant Mouse APRIL
Product Gene Name
APRIL recombinant protein
Product Synonym Gene Name
TNSF13
Product Synonym Names
Mouse APRIL Recombinant Protein
Sequence
AVLTQKHKKK HSVLHLVPVN ITSKADSDVT EVMWQPVLRR GRGLEAQGDI VRVWDTGIYL LYSQVLFHDV TFTMGQVVSR EGQGRRETLF RCIRSMPSDP DRAYNSCYSA GVFHLHQGDI ITVKIPRANA KLSLSPHGTF LGFVKL (146)
Host
Yeast
Form/Format
Lyophilized
Preparation and Storage
Store at -20 degree C.
Molecular Weight
16.4 kDa
Contains
Recombinant proteins produced in yeast.

Product Categories/Family for APRIL recombinant protein

Recombinant Proteins; ELISA Standards
Application Notes for APRIL recombinant protein
The Mouse APRIL protein can be used in cell culture, such as an APRIL ELISA Standard, and as a Western Blot Control.

Other Notes

Small volumes of APRIL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APRIL purchase

MBS258221 is a recombinant protein targeting APRIL. Also known as Recombinant Mouse APRIL. Host: Yeast.

Additional Details

NCBI/Uniprot data below describe general gene information for APRIL. It may not necessarily be applicable to this product.

NCBI GI #
71480046
NCBI GeneID
8741
NCBI Accession #
BAE16556.1
UniProt Related Accession #
O75888
NCBI Official Full Name
APRIL
NCBI Official Synonym Full Names
TNF superfamily member 13
NCBI Official Symbol
TNFSF13
NCBI Official Synonym Symbols
APRIL; CD256; TALL2; ZTNF2; TALL-2; TNLG7B; TRDL-1; UNQ383/PRO715
Protein Family
Tumor necrosis factor ligand superfamily
NCBI Protein Information
tumor necrosis factor ligand superfamily member 13

NCBI Summary for APRIL

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
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Research Articles on APRIL

1. Authors have investigated the roles of APRIL (tumor necrosis factor superfamily member [TNFSF] 13) and BAFF (TNFSF13B) in intestinal Ig induction. Peyer's patches (PPs) are, at least in part, an inductive site for Igs, including IgA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with APRIL recombinant protein

 Reference Product  PubMed Publications
 TNFRSF17 recombinant protein  >64 publications with APRIL and TNFRSF17
 TNFRSF13B recombinant protein  >50 publications with APRIL and TNFRSF13B
 SET recombinant protein  >8 publications with APRIL and SET
 TRAF3 recombinant protein  >1 publications with APRIL and TRAF3

Pathways associated with APRIL recombinant protein

 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HuR (ELAVL1) Binds And Stabilizes MRNA Pathway antibodies  HuR (ELAVL1) Binds And Stabilizes MRNA Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies  Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram

Diseases associated with APRIL recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >246 publications with APRIL and Necrosis
 Inflammation Antibodies  >24 publications with APRIL and Inflammation
 Disease Models, Animal Antibodies  >17 publications with APRIL and Disease Models, Animal
 Death Antibodies  >16 publications with APRIL and Death
 Nervous System Diseases Antibodies  >13 publications with APRIL and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >12 publications with APRIL and Cardiovascular Diseases
 Colorectal Neoplasms Antibodies  >12 publications with APRIL and Colorectal Neoplasms
 Kidney Diseases Antibodies  >8 publications with APRIL and Kidney Diseases
 Proteinuria Antibodies  >6 publications with APRIL and Proteinuria
 Liver Neoplasms Antibodies  >6 publications with APRIL and Liver Neoplasms

Organs/Tissues associated with APRIL recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >184 publications with APRIL and Blood
 Bone Antibodies  >27 publications with APRIL and Bone
 Spleen Antibodies  >17 publications with APRIL and Spleen
 Kidney Antibodies  >14 publications with APRIL and Kidney
 Lung Antibodies  >13 publications with APRIL and Lung
 Lymph Node Antibodies  >9 publications with APRIL and Lymph Node
 Skin Antibodies  >7 publications with APRIL and Skin
 Liver Antibodies  >7 publications with APRIL and Liver
 Vascular Antibodies  >5 publications with APRIL and Vascular
 Mouth Antibodies  >4 publications with APRIL and Mouth
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