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Phosphor-Extracellular Signal-Regulated Kinase (p-ERK) ELISA Kit for Porcine

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS260647

MBS260647 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the phosphor-extracellular signal-regulated kinase (p-ERK) ELISA Kit target analytes in biological samples. The concentration… More details

$370 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
phosphor-extracellular signal-regulated kinase (p-ERK), ELISA Kit
Full Product Name
Porcine phosphor-extracellular signal-regulated kinase (p-ERK) ELISA Kit
Product Gene Name
p-ERK elisa kit
Species Reactivity
Porcine
Preparation and Storage
Store all reagents at 2-8 degree C.
Molecular Weight
122,828 Da
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of p-ERK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for p-ERK. It may not necessarily be applicable to this product.

NCBI GI #
29789275
NCBI GeneID
24629
NCBI Accession #
NP_113713.1
UniProt Secondary Accession #
Q8R406; Q925F7
UniProt Related Accession #
Q05030
GenBank Nucleotide #
NM_031525.1
NCBI Official Full Name
platelet-derived growth factor receptor beta
NCBI Official Synonym Full Names
platelet derived growth factor receptor, beta polypeptide
NCBI Official Symbol
Pdgfrb
NCBI Official Synonym Symbols
PDGFR-1
UniProt Protein Name
Platelet-derived growth factor receptor beta
UniProt Synonym Protein Names
Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; PDGFR-1; CD_antigen: CD140b
UniProt Gene Name
Pdgfrb
UniProt Synonym Gene Names
Pdgfr; Pdgfr1; PDGF-R-beta; PDGFR-beta; PDGFR-1
UniProt Entry Name
PGFRB_RAT
NCBI Protein Information
platelet-derived growth factor receptor beta; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta platelet-derived growth factor receptor; Platelet-derived growth factor receptor, beta; beta-type platelet-derived growth factor receptor; platelet-derived growth factor receptor beta variant 1

NCBI Summary for p-ERK

binds platelet derived growth factor BB homodimer [RGD, Feb 2006]

UniProt Comments for p-ERK

PDGFRB: a receptor tyrosine kinase of the PDGFR family that binds members of the platelet-derived growth factor family. The identity of the growth factor bound determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGFR-alpha and -beta. Ligand binding induces receptor dimerization and autophosphorylation, thereby recruiting SH2-containing proteins including Grb2, Src, GAP, PTPN11, PI3 kinase, PLC-gamma and Nck. Regulates cell growth, actin reorganization, migration and differentiation. A variety of myeloproliferative disorders and cancers result from translocations that activate PDGFRbeta by fusion with proteins such as TEL/ETV6, H2, CEV14/TRP11, rabaptin 5, and huntington interacting protein 1. Gleevec treatment of TEL fusions has been successful. Overexpressed in metastatic medulloblastoma. Inhibitors: Gleevec, Sutent.

Protein type: Membrane protein, integral; EC 2.7.10.1; Protein kinase, TK; Oncoprotein; Kinase, protein; Protein kinase, tyrosine (receptor); TK group; PDGFR family
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Research Articles on p-ERK

1. During myocardial fibrosis of desoxycorticosterone induced salt-sensitive hypertensive rats, PDGFRalpha acts at early stage, but PDGFRbeta functions in the whole process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with p-ERK elisa kit

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram

Diseases associated with p-ERK elisa kit

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >340 publications with p-ERK and Fibrosis
 Cardiovascular Diseases Antibodies  >276 publications with p-ERK and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >240 publications with p-ERK and Disease Models, Animal
 Brain Diseases Antibodies  >183 publications with p-ERK and Brain Diseases
 Atherosclerosis Antibodies  >158 publications with p-ERK and Atherosclerosis
 Lung Diseases Antibodies  >158 publications with p-ERK and Lung Diseases
 Inflammation Antibodies  >157 publications with p-ERK and Inflammation
 Kidney Diseases Antibodies  >156 publications with p-ERK and Kidney Diseases
 Liver Diseases Antibodies  >154 publications with p-ERK and Liver Diseases
 Necrosis Antibodies  >154 publications with p-ERK and Necrosis

Organs/Tissues associated with p-ERK elisa kit

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >314 publications with p-ERK and Kidney
 Lung Antibodies  >290 publications with p-ERK and Lung
 Brain Antibodies  >284 publications with p-ERK and Brain
 Embryonic Tissue Antibodies  >250 publications with p-ERK and Embryonic Tissue
 Connective Tissue Antibodies  >172 publications with p-ERK and Connective Tissue
 Heart Antibodies  >155 publications with p-ERK and Heart
 Eye Antibodies  >104 publications with p-ERK and Eye
 Prostate Antibodies  >60 publications with p-ERK and Prostate
 Ovary Antibodies  >47 publications with p-ERK and Ovary
 Colon Antibodies  >41 publications with p-ERK and Colon
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