Anti-Q-Ab (Q-Ab) ELISA Kit for Rat

Name: Rat Q-Ab ELISA Kit; Anti-Q-Ab; MyBioSource
Brand: MyBioSource
SKU: MBS262154
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS262154

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antigen is Rat anti-Q-Ab antigen.Samples and antigen are added into ELISA plate wells and washed out with PBS or TBS. Then… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Product Name

anti-Q-Ab, ELISA Kit

Full Product Name

Rat anti-Q-Ab ELISA Kit

Product Gene Name

Q-Ab elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Serum, plasma or cell culture supernatant

Detection Range

20 ng/ml-0.312 ng/ml

Sensitivity

Up to 0.06 ng/ml.

Specificity

No cross-reaction with other factors.

Preparation and Storage

Store all reagents at 2-8 degree C.

Inter-assay Precision

<= 12%

Intra-assay Precision

<= 8%

Molecular Weight

56,576 Da

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Q-Ab elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Q-Ab purchase

MBS262154 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the anti-Q-Ab, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Q-Ab. The ELISA analytical biochemical technique of the MBS262154 kit is based on Q-Ab antibody-Q-Ab antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Q-Ab antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Q-Ab. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Q-Ab. It may not necessarily be applicable to this product.

NCBI GI #

31982508

NCBI GeneID

11601

NCBI Accession #

NP_031452.2

UniProt Secondary Accession #

Q3U1A1; Q9D2D2

UniProt Related Accession #

O35608

GenBank Nucleotide #

NM_007426.4

NCBI Official Full Name

angiopoietin-2

NCBI Official Synonym Full Names

angiopoietin 2

NCBI Official Symbol

Angpt2

NCBI Official Synonym Symbols

Ang2; Agpt2; Ang-2

UniProt Protein Name

Angiopoietin-2

UniProt Gene Name

Angpt2

UniProt Synonym Gene Names

Agpt2; ANG-2

UniProt Entry Name

ANGP2_MOUSE

NCBI Protein Information

angiopoietin-2

NCBI Summary for Q-Ab

This gene encodes an endothelial cell (EC)-derived regulator of angiogenesis and ligand for endothelial-specific receptor tyrosine kinase. The encoded protein acts as an anti-apoptotic factor for stressed ECs and a proapoptotic factor for resting ECs. [provided by RefSeq, Jan 2013]

UniProt Comments for Q-Ab

ANGPT2: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Interacts with TEK/TIE2, competing for the same binding site as ANGPT1. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; cell projection; plasma membrane; extracellular region; nucleus

Molecular Function: protein binding; metal ion binding; receptor tyrosine kinase binding; vascular endothelial growth factor receptor binding

Biological Process: Tie receptor signaling pathway; multicellular organismal development; negative regulation of blood vessel endothelial cell migration; regulation of angiogenesis; negative regulation of positive chemotaxis; negative regulation of angiogenesis; positive regulation of angiogenesis; blood vessel morphogenesis; hemopoiesis; blood vessel remodeling; angiogenesis; cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; endoderm development

Research Articles on Q-Ab

1. ANG2 as the first essential regulator of the functionally important interendothelial cell-cell junctions that form during lymphatic development

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Q-Ab elisa kit

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
HIF-1 Signaling Pathway antibodies	HIF-1 Signaling Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram
Rap1 Signaling Pathway antibodies	Rap1 Signaling Pathway Diagram
Rap1 Signaling Pathway antibodies	Rap1 Signaling Pathway Diagram
Ras Signaling Pathway antibodies	Ras Signaling Pathway Diagram
Tie2 Signaling Pathway antibodies	Tie2 Signaling Pathway Diagram

Diseases associated with Q-Ab elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>259 publications with Q-Ab and Cardiovascular Diseases
Inflammation Antibodies	>217 publications with Q-Ab and Inflammation
Disease Models, Animal Antibodies	>160 publications with Q-Ab and Disease Models, Animal
Necrosis Antibodies	>113 publications with Q-Ab and Necrosis
Liver Diseases Antibodies	>83 publications with Q-Ab and Liver Diseases
Neoplasms, Experimental Antibodies	>79 publications with Q-Ab and Neoplasms, Experimental
Heart Diseases Antibodies	>77 publications with Q-Ab and Heart Diseases
Liver Neoplasms Antibodies	>76 publications with Q-Ab and Liver Neoplasms
Hypertension Antibodies	>71 publications with Q-Ab and Hypertension
Kidney Diseases Antibodies	>68 publications with Q-Ab and Kidney Diseases

Organs/Tissues associated with Q-Ab elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>178 publications with Q-Ab and Muscle
Embryonic Tissue Antibodies	>141 publications with Q-Ab and Embryonic Tissue
Brain Antibodies	>138 publications with Q-Ab and Brain
Lung Antibodies	>135 publications with Q-Ab and Lung
Kidney Antibodies	>106 publications with Q-Ab and Kidney
Eye Antibodies	>91 publications with Q-Ab and Eye
Bone Marrow Antibodies	>61 publications with Q-Ab and Bone Marrow
Skin Antibodies	>53 publications with Q-Ab and Skin
Ovary Antibodies	>51 publications with Q-Ab and Ovary
Uterus Antibodies	>48 publications with Q-Ab and Uterus