High Density Lipoprotein Cholesterol (HDL-C) ELISA Kit for Human

Name: Human HDL-C ELISA Kit; High Density Lipoprotein Cholesterol; MyBioSource
Brand: MyBioSource
SKU: MBS263349
Price: 340 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS263349

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human HDL-C monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and… More details

$340 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

high density lipoprotein cholesterol (HDL-C), ELISA Kit

Full Product Name

Human high density lipoprotein cholesterol (HDL-C) ELISA Kit

Product Gene Name

HDL-C elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Human serum, plasma or cell culture supernatant and organizations in the natural and recombinant HDL-C concentration.

Detection Range

100 ng/ml-1.56 ng/ml

Sensitivity

Up to 0.5 ng/ml.

Specificity

No cross-reaction with other factors.

Preparation and Storage

Store all reagents at 2-8 degree C.

Inter-assay Precision

<= 12%

Intra-assay Precision

<= 8%

Molecular Weight

55,914 Da

OMIM

614025

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HDL-C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HDL-C purchase

MBS263349 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the high density lipoprotein cholesterol (HDL-C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HDL-C. The ELISA analytical biochemical technique of the MBS263349 kit is based on HDL-C antibody-HDL-C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HDL-C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HDL-C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HDL-C. It may not necessarily be applicable to this product.

NCBI GI #

317373430

NCBI GeneID

3990

NCBI Accession #

P11150.3

UniProt Secondary Accession #

O43571; P78529; Q99465; A2RUB4; A8K9B6

UniProt Related Accession #

P11150

NCBI Official Full Name

Hepatic triacylglycerol lipase

NCBI Official Synonym Full Names

lipase, hepatic

NCBI Official Symbol

LIPC

NCBI Official Synonym Symbols

HL; HTGL; LIPH; HDLCQ12

UniProt Protein Name

Hepatic triacylglycerol lipase

UniProt Synonym Protein Names

Lipase member C

UniProt Gene Name

LIPC

UniProt Synonym Gene Names

HTGL; HL; Hepatic lipase

UniProt Entry Name

LIPC_HUMAN

NCBI Protein Information

hepatic triacylglycerol lipase; hepatic lipase; lipase member C

NCBI Summary for HDL-C

LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008]

UniProt Comments for HDL-C

LIPC: Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin. Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency). A disorder characterized by elevated levels of beta-migrating very low density lipoproteins, and abnormally triglyceride-rich low and high density lipoproteins. Belongs to the AB hydrolase superfamily. Lipase family.

Protein type: Lipid Metabolism - glycerolipid; Phospholipase; Secreted; Secreted, signal peptide; EC 3.1.1.3

Chromosomal Location of Human Ortholog: 15q21-q23

Cellular Component: extracellular space

Molecular Function: heparin binding; triacylglycerol lipase activity; low-density lipoprotein binding; apolipoprotein binding; phospholipase activity

Biological Process: cholesterol metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol catabolic process; fatty acid biosynthetic process

Disease: High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 12; Hepatic Lipase Deficiency; Diabetes Mellitus, Noninsulin-dependent

Research Articles on HDL-C

1. The findings suggest that LIPC and LPL genes could both modify the risk for AMD and the metabolism of lutein and zeaxanthin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HDL-C elisa kit

Reference Product	PubMed Publications
APOE elisa kit	>41 publications with HDL-C and APOE
APOB elisa kit	>38 publications with HDL-C and APOB
LDLR elisa kit	>15 publications with HDL-C and LDLR
LIPF elisa kit	>1 publications with HDL-C and LIPF
DGAT1 elisa kit	>1 publications with HDL-C and DGAT1

Pathways associated with HDL-C elisa kit

Products by Pathway	Pathway Diagram
Acylglycerol Degradation Pathway antibodies	Acylglycerol Degradation Pathway Diagram
Acylglycerol Degradation Pathway antibodies	Acylglycerol Degradation Pathway Diagram
Chylomicron-mediated Lipid Transport Pathway antibodies	Chylomicron-mediated Lipid Transport Pathway Diagram
Fatty Acid Beta Oxidation Pathway antibodies	Fatty Acid Beta Oxidation Pathway Diagram
Glycerolipid Metabolism Pathway antibodies	Glycerolipid Metabolism Pathway Diagram
Glycerolipid Metabolism Pathway antibodies	Glycerolipid Metabolism Pathway Diagram
Lipid Digestion, Mobilization, And Transport Pathway antibodies	Lipid Digestion, Mobilization, And Transport Pathway Diagram
Lipoprotein Metabolism Pathway antibodies	Lipoprotein Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with HDL-C elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>83 publications with HDL-C and Cardiovascular Diseases
Atherosclerosis Antibodies	>45 publications with HDL-C and Atherosclerosis
Dyslipidemias Antibodies	>34 publications with HDL-C and Dyslipidemias
Brain Diseases Antibodies	>25 publications with HDL-C and Brain Diseases
Hyperlipidemias Antibodies	>23 publications with HDL-C and Hyperlipidemias
Insulin Resistance Antibodies	>20 publications with HDL-C and Insulin Resistance
Diabetes Mellitus, Type 2 Antibodies	>19 publications with HDL-C and Diabetes Mellitus, Type 2
Liver Diseases Antibodies	>14 publications with HDL-C and Liver Diseases
Fatty Liver Antibodies	>11 publications with HDL-C and Fatty Liver
Hypertriglyceridemia Antibodies	>10 publications with HDL-C and Hypertriglyceridemia

Organs/Tissues associated with HDL-C elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>81 publications with HDL-C and Liver
Brain Antibodies	>48 publications with HDL-C and Brain
Heart Antibodies	>44 publications with HDL-C and Heart
Lung Antibodies	>9 publications with HDL-C and Lung
Kidney Antibodies	>6 publications with HDL-C and Kidney
Mammary Gland Antibodies	>1 publications with HDL-C and Mammary Gland