Leukocyte Antigen A (HLA-A) ELISA Kit for Mouse

Name: Mouse HLA-A ELISA Kit; Leukocyte Antigen A; MyBioSource
Brand: MyBioSource
SKU: MBS265477
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS265477

MBS265477 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the leukocyte antigen A (HLA-A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$350 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

leukocyte antigen A (HLA-A), ELISA Kit

Full Product Name

Mouse leukocyte antigen A (HLA-A) ELISA Kit

Product Gene Name

HLA-A elisa kit

Species Reactivity

Mouse

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

33,845 Da

OMIM

601028

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HLA-A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HLA-A. It may not necessarily be applicable to this product.

NCBI GI #

38683836

NCBI GeneID

961

NCBI Accession #

NP_942088.1

UniProt Secondary Accession #

Q53Y71; Q96A60; A8K198; D3DN59

UniProt Related Accession #

Q08722

GenBank Nucleotide #

NM_198793.2

NCBI Official Full Name

leukocyte surface antigen CD47 isoform 2

NCBI Official Synonym Full Names

CD47 molecule

NCBI Official Symbol

CD47

NCBI Official Synonym Symbols

IAP; OA3; MER6

UniProt Protein Name

Leukocyte surface antigen CD47

UniProt Synonym Protein Names

Antigenic surface determinant protein OA3; Integrin-associated protein; IAP; Protein MER6; CD_antigen: CD47

Protein Family

HLA class I histocompatibility antigen

UniProt Gene Name

CD47

UniProt Synonym Gene Names

MER6; IAP

UniProt Entry Name

CD47_HUMAN

NCBI Protein Information

leukocyte surface antigen CD47; CD47 glycoprotein; Rh-related antigen; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; antigenic surface determinant protein OA3; antigen identified by monoclonal antibody 1D8; CD47 antigen (Rh-related antigen, integrin-associated signal transducer)

NCBI Summary for HLA-A

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

UniProt Comments for HLA-A

CD47: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q13.1-q13.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; response to bacterium; positive regulation of phagocytosis; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; opsonization; positive regulation of T cell activation; blood coagulation; cell adhesion; leukocyte migration; positive regulation of inflammatory response

Research Articles on HLA-A

1. Suppression of CD47 by morpholino approach suppressed growth of hepatocellular carcinoma in vivo and exerted a chemosensitization effect through blockade of CTSS/PAR2 signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HLA-A elisa kit

Reference Product	PubMed Publications
THBS1 elisa kit	>140 publications with HLA-A and THBS1
SIRPA elisa kit	>69 publications with HLA-A and SIRPA
RHAG elisa kit	>22 publications with HLA-A and RHAG
PTPN11 elisa kit	>7 publications with HLA-A and PTPN11
SIRPB1 elisa kit	>5 publications with HLA-A and SIRPB1
SIRPG elisa kit	>3 publications with HLA-A and SIRPG
THBS2 elisa kit	>1 publications with HLA-A and THBS2
ITGB3 elisa kit	>1 publications with HLA-A and ITGB3
ITGAV elisa kit	>1 publications with HLA-A and ITGAV

Pathways associated with HLA-A elisa kit

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
ECM-receptor Interaction Pathway antibodies	ECM-receptor Interaction Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Integrin Cell Surface Interactions Pathway antibodies	Integrin Cell Surface Interactions Pathway Diagram
Integrins In Angiogenesis Pathway antibodies	Integrins In Angiogenesis Pathway Diagram
Signal Regulatory Protein (SIRP) Family Interactions Pathway antibodies	Signal Regulatory Protein (SIRP) Family Interactions Pathway Diagram
Spinal Cord Injury Pathway antibodies	Spinal Cord Injury Pathway Diagram

Diseases associated with HLA-A elisa kit

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>82 publications with HLA-A and Immune System Diseases
Inflammation Antibodies	>78 publications with HLA-A and Inflammation
Disease Models, Animal Antibodies	>45 publications with HLA-A and Disease Models, Animal
Anemia Antibodies	>43 publications with HLA-A and Anemia
Necrosis Antibodies	>40 publications with HLA-A and Necrosis
Nervous System Diseases Antibodies	>32 publications with HLA-A and Nervous System Diseases
Brain Diseases Antibodies	>27 publications with HLA-A and Brain Diseases
Neoplasms, Experimental Antibodies	>22 publications with HLA-A and Neoplasms, Experimental
Respiratory Tract Diseases Antibodies	>14 publications with HLA-A and Respiratory Tract Diseases
Breast Neoplasms Antibodies	>10 publications with HLA-A and Breast Neoplasms

Organs/Tissues associated with HLA-A elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>426 publications with HLA-A and Blood
Vascular Antibodies	>104 publications with HLA-A and Vascular
Bone Antibodies	>74 publications with HLA-A and Bone
Bone Marrow Antibodies	>61 publications with HLA-A and Bone Marrow
Muscle Antibodies	>54 publications with HLA-A and Muscle
Brain Antibodies	>54 publications with HLA-A and Brain
Lung Antibodies	>27 publications with HLA-A and Lung
Liver Antibodies	>27 publications with HLA-A and Liver
Spleen Antibodies	>27 publications with HLA-A and Spleen
Skin Antibodies	>26 publications with HLA-A and Skin