Vitamin K1 (VK1) ELISA Kit for Rat

Name: Rat VK1 ELISA Kit; Vitamin K1; MyBioSource
Brand: MyBioSource
SKU: MBS266013
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS266013

MBS266013 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Vitamin K1 (VK1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive… More details

$350 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Vitamin K1 (VK1), ELISA Kit

Full Product Name

Rat Vitamin K1 (VK1) ELISA kit

Product Gene Name

VK1 elisa kit

Species Reactivity

Rat

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

17,783 Da

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of VK1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VK1. It may not necessarily be applicable to this product.

NCBI GI #

42627871

NCBI GeneID

309004

NCBI Accession #

NP_976080.1

UniProt Related Accession #

Q6TEK4

GenBank Nucleotide #

NM_203335.2

NCBI Official Full Name

vitamin K epoxide reductase complex subunit 1

NCBI Official Synonym Full Names

vitamin K epoxide reductase complex, subunit 1

NCBI Official Symbol

Vkorc1

UniProt Protein Name

Vitamin K epoxide reductase complex subunit 1

UniProt Synonym Protein Names

Vitamin K1 2,3-epoxide reductase subunit 1

UniProt Gene Name

Vkorc1

UniProt Entry Name

VKOR1_RAT

NCBI Protein Information

vitamin K epoxide reductase complex subunit 1; Warfarin resistance; phylloquinone epoxide reductase; vitamin K1 2,3-epoxide reductase subunit 1; vitamin K1 epoxide reductase (warfarin-sensitive)

NCBI Summary for VK1

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. [provided by RefSeq, Jul 2008]

UniProt Comments for VK1

Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.

Research Articles on VK1

1. The aim of this study was to determine the distribution of VKORC1 1173C > T and VKORC1 -1639G > A polymorphisms, which are most important for warfarin therapy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with VK1 elisa kit

Products by Pathway	Pathway Diagram
Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway antibodies	Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies	PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway antibodies	Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway Diagram
Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway antibodies	Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway Diagram

Diseases associated with VK1 elisa kit

Disease Name	Pubmed Publications
Vascular Diseases Antibodies	>121 publications with VK1 and Vascular Diseases
Hemorrhage Antibodies	>73 publications with VK1 and Hemorrhage
Heart Diseases Antibodies	>54 publications with VK1 and Heart Diseases
Stroke Antibodies	>27 publications with VK1 and Stroke
Blood Coagulation Disorders Antibodies	>17 publications with VK1 and Blood Coagulation Disorders
Coronary Disease Antibodies	>10 publications with VK1 and Coronary Disease
Drug-Related Side Effects and Adverse Reactions Antibodies	>10 publications with VK1 and Drug-Related Side Effects and Adverse Reactions
Coumarin Resistance Antibodies	>8 publications with VK1 and Coumarin Resistance
Liver Diseases Antibodies	>7 publications with VK1 and Liver Diseases
Congenital Abnormalities Antibodies	>4 publications with VK1 and Congenital Abnormalities

Organs/Tissues associated with VK1 elisa kit

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>73 publications with VK1 and Heart
Liver Antibodies	>29 publications with VK1 and Liver
Artery Antibodies	>15 publications with VK1 and Artery
Kidney Antibodies	>12 publications with VK1 and Kidney
Lung Antibodies	>7 publications with VK1 and Lung
Eye Antibodies	>2 publications with VK1 and Eye
Connective Tissue Antibodies	>2 publications with VK1 and Connective Tissue
Nerve Antibodies	>1 publications with VK1 and Nerve
Prostate Antibodies	>1 publications with VK1 and Prostate
Embryonic Tissue Antibodies	>1 publications with VK1 and Embryonic Tissue