• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CXC-Chemokine Receptor 1 (CXCR1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS266284

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human CXCR1 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and… More details

$340 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CXC-chemokine receptor 1 (CXCR1), ELISA Kit
Full Product Name
Human CXC-chemokine receptor 1 (CXCR1) ELISA Kit
Product Gene Name
CXCR1 elisa kit
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma or cell culture supernatant and organizations in the natural and recombinant CXCR1 concentration.
Detection Range
20 ng/ml-0.312 ng/ml
Sensitivity
0.06 ng/ml.
Specificity
No cross-reaction with other factors.
Preparation and Storage
Store all reagents at 2-8 degree C.
Inter-assay Precision
<= 12%
Intra-assay Precision
<= 8%
Molecular Weight
40,032 Da
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of CXCR1 elisa kit

Human CXCR1 ELISA Kit – Cat# MBS266284

Other Notes

Small volumes of CXCR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCR1 purchase

MBS266284 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CXC-chemokine receptor 1 (CXCR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CXCR1. The ELISA analytical biochemical technique of the MBS266284 kit is based on CXCR1 antibody-CXCR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CXCR1. It may not necessarily be applicable to this product.

NCBI GI #
30142679
NCBI GeneID
227288
NCBI Accession #
NP_839972.1
UniProt Related Accession #
Q810W6
GenBank Nucleotide #
NM_178241.4
NCBI Official Full Name
C-X-C chemokine receptor type 1
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 1
NCBI Official Symbol
Cxcr1
NCBI Official Synonym Symbols
Il8ra
UniProt Protein Name
C-X-C chemokine receptor type 1
UniProt Synonym Protein Names
High affinity interleukin-8 receptor A; IL-8R A; CD_antigen: CD181
Protein Family
C-X-C chemokine receptor
UniProt Gene Name
Cxcr1
UniProt Synonym Gene Names
Il8ra; CXC-R1; CXCR-1; IL-8R A
UniProt Entry Name
CXCR1_MOUSE
NCBI Protein Information
C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; IL-8R A; CXC chemokine receptor 1; interleukin 8 receptor, alpha; high affinity interleukin-8 receptor A

UniProt Comments for CXCR1

IL8RA: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, cytokine; Membrane protein, integral; Receptor, GPCR

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; signal transducer activity; interleukin-8 receptor activity; chemokine receptor activity; interleukin-8 binding; C-X-C chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; cell surface receptor linked signal transduction; receptor internalization; signal transduction; chemotaxis
Show more

Research Articles on CXCR1

1. Pharmacologic blockade of CXCR1/2 as well as genetic deletion of NAP-2 markedly reduced leukocyte shape change and intrathrombus migration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CXCR1 elisa kit

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram

Diseases associated with CXCR1 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >205 publications with CXCR1 and Inflammation
 Neoplasms Antibodies  >124 publications with CXCR1 and Neoplasms
 Lung Diseases Antibodies  >74 publications with CXCR1 and Lung Diseases
 Necrosis Antibodies  >65 publications with CXCR1 and Necrosis
 Skin Diseases Antibodies  >39 publications with CXCR1 and Skin Diseases
 Nervous System Diseases Antibodies  >30 publications with CXCR1 and Nervous System Diseases
 Kidney Diseases Antibodies  >18 publications with CXCR1 and Kidney Diseases
 Liver Diseases Antibodies  >18 publications with CXCR1 and Liver Diseases
 Brain Diseases Antibodies  >16 publications with CXCR1 and Brain Diseases
 Neoplasms, Experimental Antibodies  >15 publications with CXCR1 and Neoplasms, Experimental

Organs/Tissues associated with CXCR1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Extraembryonic Tissue Antibodies  >2 publications with CXCR1 and Extraembryonic Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000