Insulin Like Growth Factor Binding Protein 2 (IGFBP-2) ELISA Kit for Rat

Name: Rat IGFBP-2 ELISA Kit; Insulin Like Growth Factor Binding Protein 2; MyBioSource
Brand: MyBioSource
SKU: MBS268113
Price: 350 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS268113

Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Rat IGFBP-2 monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and… More details

$350 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Insulin Like Growth Factor Binding Protein 2 (IGFBP-2), ELISA Kit

Full Product Name

Rat Insulin Like Growth Factor Binding Protein 2 (IGFBP-2) ELISA Kit

Product Gene Name

IGFBP-2 elisa kit

Species Reactivity

Rat

Assay Type

Sandwich

Detection Range

10 ng/mL-0.156 ng/mL

Sensitivity

Up to 0.05 ng/mL

Preparation and Storage

Store all reagents at 2-8 degree C.

Inter-assay Precision

<= 12%

Intra-assay Precision

<= 8%

Molecular Weight

34,814 Da

OMIM

146731

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IGFBP-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGFBP-2 purchase

MBS268113 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin Like Growth Factor Binding Protein 2 (IGFBP-2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IGFBP-2. The ELISA analytical biochemical technique of the MBS268113 kit is based on IGFBP-2 antibody-IGFBP-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFBP-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFBP-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IGFBP-2. It may not necessarily be applicable to this product.

NCBI GI #

55925576

NCBI GeneID

3485

NCBI Accession #

NP_000588.2

UniProt Secondary Accession #

Q14619; Q9UCL3

UniProt Related Accession #

P18065

GenBank Nucleotide #

NM_000597.2

NCBI Official Full Name

insulin-like growth factor-binding protein 2

NCBI Official Synonym Full Names

insulin-like growth factor binding protein 2, 36kDa

NCBI Official Symbol

IGFBP2

NCBI Official Synonym Symbols

IBP2; IGF-BP53

UniProt Protein Name

Insulin-like growth factor-binding protein 2

UniProt Gene Name

IGFBP2

UniProt Synonym Gene Names

BP2; IBP2; IBP-2; IGF-binding protein 2; IGFBP-2

UniProt Entry Name

IBP2_HUMAN

NCBI Protein Information

insulin-like growth factor-binding protein 2; IBP-2; IGFBP-2; IGF-binding protein 2

UniProt Comments for IGFBP-2

IGFBP2: Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Binds IGF2 more than IGF1.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: extracellular space; apical plasma membrane; extracellular region; cytoplasmic vesicle

Molecular Function: protein binding; insulin-like growth factor I binding; insulin-like growth factor II binding

Biological Process: response to drug; regulation of insulin-like growth factor receptor signaling pathway; response to retinoic acid; response to lithium ion; response to glucocorticoid stimulus; female pregnancy; signal transduction; positive regulation of activated T cell proliferation; response to estradiol stimulus; cellular response to hormone stimulus; cellular protein metabolic process; response to mechanical stimulus; regulation of cell growth; response to nutrient; aging

Research Articles on IGFBP-2

1. insulin-like growth factors bound to IGFBP-3 remain in the circulation, whereas those bound to IGFBP-2 freely reach target tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IGFBP-2 elisa kit

Reference Product	PubMed Publications
IGF1 elisa kit	>43 publications with IGFBP-2 and IGF1
IGF2 elisa kit	>39 publications with IGFBP-2 and IGF2
FGF2 elisa kit	>11 publications with IGFBP-2 and FGF2
INS elisa kit	>4 publications with IGFBP-2 and INS
MEN1 elisa kit	>2 publications with IGFBP-2 and MEN1
MIIP elisa kit	>1 publications with IGFBP-2 and MIIP

Pathways associated with IGFBP-2 elisa kit

Products by Pathway	Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies	Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram

Diseases associated with IGFBP-2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>346 publications with IGFBP-2 and Neoplasms
Carcinoma Antibodies	>97 publications with IGFBP-2 and Carcinoma
Nervous System Diseases Antibodies	>93 publications with IGFBP-2 and Nervous System Diseases
Brain Diseases Antibodies	>77 publications with IGFBP-2 and Brain Diseases
Prostatic Neoplasms Antibodies	>49 publications with IGFBP-2 and Prostatic Neoplasms
Kidney Diseases Antibodies	>49 publications with IGFBP-2 and Kidney Diseases
Adenocarcinoma Antibodies	>47 publications with IGFBP-2 and Adenocarcinoma
Breast Neoplasms Antibodies	>46 publications with IGFBP-2 and Breast Neoplasms
Cardiovascular Diseases Antibodies	>43 publications with IGFBP-2 and Cardiovascular Diseases
Liver Diseases Antibodies	>38 publications with IGFBP-2 and Liver Diseases

Organs/Tissues associated with IGFBP-2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>585 publications with IGFBP-2 and Blood
Liver Antibodies	>179 publications with IGFBP-2 and Liver
Brain Antibodies	>141 publications with IGFBP-2 and Brain
Ovary Antibodies	>122 publications with IGFBP-2 and Ovary
Bone Antibodies	>109 publications with IGFBP-2 and Bone
Muscle Antibodies	>107 publications with IGFBP-2 and Muscle
Kidney Antibodies	>102 publications with IGFBP-2 and Kidney
Prostate Antibodies	>75 publications with IGFBP-2 and Prostate
Lung Antibodies	>67 publications with IGFBP-2 and Lung
Embryonic Tissue Antibodies	>61 publications with IGFBP-2 and Embryonic Tissue