Chemerin (CHE) ELISA Kit for Sheep

Name: Sheep CHE ELISA Kit; Chemerin; MyBioSource
Brand: MyBioSource
SKU: MBS026980
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS026980

MBS026980 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chemerin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Chemerin, ELISA Kit

Full Product Name

Sheep Chemerin ELISA Kit

Product Gene Name

CHE elisa kit

Species Reactivity

Sheep

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

42,322 Da

OMIM

602351

3D Structure

ModBase 3D Structure for Q99788

Other Notes

Small volumes of CHE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHE. It may not necessarily be applicable to this product.

NCBI GI #

215272321

NCBI GeneID

1240

NCBI Accession #

NP_001135817.1

UniProt Primary Accession #

Q99788

UniProt Secondary Accession #

O75748; Q3KP37; Q5U0H0; Q99789; A8K6Y5

UniProt Related Accession #

Q99788

GenBank Nucleotide #

NM_001142345.1

NCBI Official Full Name

chemokine-like receptor 1 isoform a

NCBI Official Synonym Full Names

chemokine-like receptor 1

NCBI Official Symbol

CMKLR1

NCBI Official Synonym Symbols

DEZ; RVER1; ChemR23; CHEMERINR

UniProt Protein Name

Chemokine-like receptor 1

UniProt Synonym Protein Names

G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ

Protein Family

Retinoic acid receptor responder protein

UniProt Gene Name

CMKLR1

UniProt Synonym Gene Names

CHEMR23; DEZ

UniProt Entry Name

CML1_HUMAN

NCBI Protein Information

chemokine-like receptor 1; chemerin receptor; resolvin E1 receptor; chemokine receptor-like 1; G-protein coupled receptor DEZ; G-protein coupled receptor ChemR23; orphan G-protein coupled receptor, Dez

UniProt Comments for CHE

CMKLR1: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF- kappa-B. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q24.1

Cellular Component: integral to plasma membrane; integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; chemokine receptor activity; receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of interleukin-12 production; inhibition of NF-kappaB transcription factor; regulation of calcium-mediated signaling; positive regulation of fat cell differentiation; immune response; chemotaxis; skeletal development

Research Articles on CHE

1. ChemR23 is expressed in neutrophil granules and rapidly upregulated upon neutrophil activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CHE elisa kit

Reference Product	PubMed Publications
RARRES2 elisa kit	>4 publications with CHE and RARRES2

Pathways associated with CHE elisa kit

Products by Pathway	Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with CHE elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>51 publications with CHE and Inflammation
Necrosis Antibodies	>12 publications with CHE and Necrosis
Insulin Resistance Antibodies	>8 publications with CHE and Insulin Resistance
Lung Diseases Antibodies	>8 publications with CHE and Lung Diseases
Liver Diseases Antibodies	>7 publications with CHE and Liver Diseases
Disease Models, Animal Antibodies	>6 publications with CHE and Disease Models, Animal
Cardiovascular Diseases Antibodies	>6 publications with CHE and Cardiovascular Diseases
Pain Antibodies	>5 publications with CHE and Pain
Fatty Liver Antibodies	>4 publications with CHE and Fatty Liver
Nervous System Diseases Antibodies	>3 publications with CHE and Nervous System Diseases

Organs/Tissues associated with CHE elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>48 publications with CHE and Blood
Adipose Tissue Antibodies	>25 publications with CHE and Adipose Tissue
Connective Tissue Antibodies	>14 publications with CHE and Connective Tissue
Bone Antibodies	>13 publications with CHE and Bone
Lung Antibodies	>11 publications with CHE and Lung
Heart Antibodies	>7 publications with CHE and Heart
Spleen Antibodies	>4 publications with CHE and Spleen
Brain Antibodies	>4 publications with CHE and Brain
Kidney Antibodies	>2 publications with CHE and Kidney
Uterus Antibodies	>2 publications with CHE and Uterus