Porcine CENPA ELISA Kit – Cat# MBS027077

Centromere Protein A (CENPA) ELISA Kit for Porcine

Name: Porcine CENPA ELISA Kit; Centromere Protein A; MyBioSource
Brand: MyBioSource
SKU: MBS027077
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS027077

MBS027077 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Centromere Protein A (CENPA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Centromere Protein A (CENPA), ELISA Kit

Full Product Name

Porcine Centromere Protein A ELISA Kit

Product Gene Name

CENPA elisa kit

Species Reactivity

Porcine

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

15,991 Da

Chromosome Location

Chromosome: 2; NC_000002.11 (27008882..27017457). Location: 2p23.3

OMIM

117139

3D Structure

ModBase 3D Structure for P49450

Other Notes

Small volumes of CENPA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CENPA. It may not necessarily be applicable to this product.

NCBI GI #

12803733

NCBI GeneID

1058

NCBI Accession #

AAH02703.1

UniProt Primary Accession #

P49450

UniProt Secondary Accession #

Q53T74; Q9BVW2; D6W544

UniProt Related Accession #

P49450

NCBI Official Full Name

CENPA protein

NCBI Official Synonym Full Names

centromere protein A

NCBI Official Symbol

CENPA

NCBI Official Synonym Symbols

CenH3; CENP-A

UniProt Protein Name

Histone H3-like centromeric protein A

UniProt Synonym Protein Names

Centromere autoantigen A; Centromere protein A

Protein Family

Histone H3-like centromeric protein

UniProt Gene Name

CENPA

UniProt Synonym Gene Names

CENP-A

UniProt Entry Name

CENPA_HUMAN

NCBI Protein Information

histone H3-like centromeric protein A; centromere autoantigen A; centromere protein A, 17kDa; centromere-specific histone

NCBI Summary for CENPA

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

UniProt Comments for CENPA

CENPA: a basic nuclear protein of the histone H3 family. May act as a core histone necessary for the assembly of centromeres. Contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: nucleoplasm; inner kinetochore of condensed chromosome; nucleosome; nucleus; cytosol; chromosome, pericentric region; condensed nuclear chromosome, pericentric region

Molecular Function: protein binding; DNA binding; protein heterodimerization activity; chromatin binding

Biological Process: nucleosome assembly; kinetochore assembly; DNA replication-independent nucleosome assembly at centromere; viral reproduction; establishment of mitotic spindle orientation; mitotic cell cycle

Research Articles on CENPA

1. And-1 together with HJURP regulates the assembly of new CENP-A onto centromeres.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CENPA elisa kit

Reference Product	PubMed Publications
AURKB elisa kit	>2 publications with CENPA and AURKB
HJURP elisa kit	>2 publications with CENPA and HJURP
NUF2 elisa kit	>1 publications with CENPA and NUF2
BIRC5 elisa kit	>1 publications with CENPA and BIRC5
CENPE elisa kit	>1 publications with CENPA and CENPE
CENPF elisa kit	>1 publications with CENPA and CENPF

Pathways associated with CENPA elisa kit

Products by Pathway	Pathway Diagram
Aurora A Signaling Pathway antibodies	Aurora A Signaling Pathway Diagram
Aurora B Signaling Pathway antibodies	Aurora B Signaling Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Chromosome Maintenance Pathway antibodies	Chromosome Maintenance Pathway Diagram
Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway antibodies	Deposition Of New CENPA-containing Nucleosomes At The Centromere Pathway Diagram
FOXM1 Transcription Factor Network Pathway antibodies	FOXM1 Transcription Factor Network Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Mitotic Anaphase Pathway antibodies	Mitotic Anaphase Pathway Diagram
Mitotic Metaphase And Anaphase Pathway antibodies	Mitotic Metaphase And Anaphase Pathway Diagram

Diseases associated with CENPA elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>9 publications with CENPA and Neoplasms
Breast Neoplasms Antibodies	>3 publications with CENPA and Breast Neoplasms
Carcinoma Antibodies	>2 publications with CENPA and Carcinoma
Pancreatic Neoplasms Antibodies	>1 publications with CENPA and Pancreatic Neoplasms
Drug Toxicity Antibodies	>1 publications with CENPA and Drug Toxicity
Adenocarcinoma Antibodies	>1 publications with CENPA and Adenocarcinoma
Cell Transformation, Neoplastic Antibodies	>1 publications with CENPA and Cell Transformation, Neoplastic
Liver Diseases Antibodies	>1 publications with CENPA and Liver Diseases
Liver Cirrhosis Antibodies	>1 publications with CENPA and Liver Cirrhosis
Lung Neoplasms Antibodies	>1 publications with CENPA and Lung Neoplasms

Organs/Tissues associated with CENPA elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with CENPA and Blood
Embryonic Tissue Antibodies	>3 publications with CENPA and Embryonic Tissue
Lymph Node Antibodies	>2 publications with CENPA and Lymph Node
Lung Antibodies	>2 publications with CENPA and Lung
Lymph Antibodies	>2 publications with CENPA and Lymph
Connective Tissue Antibodies	>1 publications with CENPA and Connective Tissue
Liver Antibodies	>1 publications with CENPA and Liver