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Y+l Amino Acid Transporter 2 (SLC7A6) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS280984

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate SLC7A6 in samples. An antibody specific for SLC7A6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySLC7A6 present is bound by… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Y+L amino acid transporter 2 (SLC7A6), ELISA Kit
Full Product Name
Mouse Y+L amino acid transporter 2 (SLC7A6) ELISA Kit
Product Gene Name
SLC7A6 elisa kit
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, Plasma, Other biological fluids
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse SLC7A6. No significant cross-reactivity or interference between Mouse SLC7A6 and analogues was observed.
Preparation and Storage
Store at 2-8 degree C.
Molecular Weight
39,901 Da
3D Structure
ModBase 3D Structure for Q8BGK6
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SLC7A6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC7A6 purchase

MBS280984 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Y+L amino acid transporter 2 (SLC7A6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC7A6. The ELISA analytical biochemical technique of the MBS280984 kit is based on SLC7A6 antibody-SLC7A6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC7A6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC7A6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for SLC7A6. It may not necessarily be applicable to this product.

NCBI GI #
30520283
NCBI GeneID
330836
NCBI Accession #
NP_848913.1
UniProt Primary Accession #
Q8BGK6
UniProt Secondary Accession #
Q3TMY5; Q3U084; Q6ZQF5; Q8CFY3
UniProt Related Accession #
Q8BGK6
GenBank Nucleotide #
NM_178798.4
NCBI Official Full Name
Y+L amino acid transporter 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
NCBI Official Symbol
Slc7a6
NCBI Official Synonym Symbols
LAT3; LAT-2; y+LAT-2; AI643885
UniProt Protein Name
Y+L amino acid transporter 2
UniProt Synonym Protein Names
Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2
Protein Family
Y+L amino acid transporter
UniProt Gene Name
Slc7a6
UniProt Synonym Gene Names
Y+LAT2; y+LAT-2
NCBI Protein Information
Y+L amino acid transporter 2

UniProt Comments for SLC7A6

SLC7A6: Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells. Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 8|8 D3

Cellular Component: integral component of membrane; integral component of plasma membrane; intracellular membrane-bound organelle; membrane; plasma membrane

Molecular Function: amino acid transmembrane transporter activity; antiporter activity; L-amino acid transmembrane transporter activity

Biological Process: amino acid transport; transport
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Research Articles on SLC7A6

1. these data help to elucidate the molecular mechanisms and role of Lat2 in thyroid hormone transport.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SLC7A6 elisa kit

 Reference Product  PubMed Publications
 Slc3a2 elisa kit  >6 publications with SLC7A6 and Slc3a2
 Slc6a14 elisa kit  >4 publications with SLC7A6 and Slc6a14
 Slc43a2 elisa kit  >3 publications with SLC7A6 and Slc43a2
 Slc1a4 elisa kit  >2 publications with SLC7A6 and Slc1a4
 Slc1a5 elisa kit  >2 publications with SLC7A6 and Slc1a5
 Slc6a19 elisa kit  >1 publications with SLC7A6 and Slc6a19
 Slc16a10 elisa kit  >1 publications with SLC7A6 and Slc16a10
 Slc3a1 elisa kit  >1 publications with SLC7A6 and Slc3a1

Pathways associated with SLC7A6 elisa kit

 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 Basigin Interactions Pathway antibodies  Basigin Interactions Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram

Diseases associated with SLC7A6 elisa kit

 Disease Name  Pubmed Publications
 Genital Diseases, Male Antibodies  >4 publications with SLC7A6 and Genital Diseases, Male
 Prostatic Diseases Antibodies  >4 publications with SLC7A6 and Prostatic Diseases
 Adenocarcinoma Antibodies  >2 publications with SLC7A6 and Adenocarcinoma
 Necrosis Antibodies  >2 publications with SLC7A6 and Necrosis
 Carcinoma, Hepatocellular Antibodies  >1 publications with SLC7A6 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >1 publications with SLC7A6 and Kidney Diseases

Organs/Tissues associated with SLC7A6 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with SLC7A6 and Blood
 Kidney Antibodies  >6 publications with SLC7A6 and Kidney
 Lung Antibodies  >4 publications with SLC7A6 and Lung
 Intestine Antibodies  >4 publications with SLC7A6 and Intestine
 Brain Antibodies  >3 publications with SLC7A6 and Brain
 Embryonic Tissue Antibodies  >3 publications with SLC7A6 and Embryonic Tissue
 Liver Antibodies  >2 publications with SLC7A6 and Liver
 Skin Antibodies  >2 publications with SLC7A6 and Skin
 Ovary Antibodies  >2 publications with SLC7A6 and Ovary
 Heart Antibodies  >1 publications with SLC7A6 and Heart
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