Potassium Voltage-Gated Channel Subfamily H Member 5 (KCNH5) ELISA Kit for Human

Name: Human KCNH5 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS281167
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS281167

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate KCNH5 in samples. An antibody specific for KCNH5 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyKCNH5 present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Potassium voltage-gated channel subfamily H member 5 (KCNH5), ELISA Kit

Full Product Name

Human Potassium voltage-gated channel subfamily H member 5 (KCNH5) ELISA Kit

Product Gene Name

KCNH5 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Human KCNH5. No significant cross-reactivity or interference between Human KCNH5 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

71,123 Da

OMIM

AF418206 mRNA

3D Structure

ModBase 3D Structure for Q8NCM2

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KCNH5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNH5 purchase

MBS281167 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Potassium voltage-gated channel subfamily H member 5 (KCNH5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KCNH5. The ELISA analytical biochemical technique of the MBS281167 kit is based on KCNH5 antibody-KCNH5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KCNH5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KCNH5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for KCNH5. It may not necessarily be applicable to this product.

NCBI GI #

22024390

NCBI GeneID

27133

NCBI Accession #

NP_647479.2

UniProt Primary Accession #

Q8NCM2

UniProt Secondary Accession #

C9JP98

UniProt Related Accession #

Q8NCM2

GenBank Nucleotide #

NM_139318.4

NCBI Official Full Name

potassium voltage-gated channel subfamily H member 5 isoform 1

NCBI Official Synonym Full Names

potassium voltage-gated channel subfamily H member 5

NCBI Official Symbol

KCNH5

NCBI Official Synonym Symbols

EAG2; hEAG2; H-EAG2; Kv10.2

UniProt Protein Name

Potassium voltage-gated channel subfamily H member 5

UniProt Synonym Protein Names

Ether-a-go-go potassium channel 2; hEAG2; Voltage-gated potassium channel subunit Kv10.2

Protein Family

Potassium voltage-gated channel subfamily

UniProt Gene Name

KCNH5

UniProt Synonym Gene Names

EAG2; hEAG2

NCBI Protein Information

potassium voltage-gated channel subfamily H member 5

NCBI Summary for KCNH5

This gene encodes a member of voltage-gated potassium channels. Members of this family have diverse functions, including regulating neurotransmitter and hormone release, cardiac function, and cell volume. This protein is an outward-rectifying, noninactivating channel. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

UniProt Comments for KCNH5

Kv10.2: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly. Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.2/KCNH5 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q23.2

Cellular Component: cell surface; integral component of plasma membrane; intracellular; plasma membrane

Molecular Function: calmodulin binding; phosphorelay sensor kinase activity; protein heterodimerization activity; voltage-gated potassium channel activity

Biological Process: regulation of G2/M transition of mitotic cell cycle; regulation of membrane potential; two-component signal transduction system (phosphorelay)

Research Articles on KCNH5

1. EAG2 potassium channel has an evolutionarily conserved function for promoting brain tumor growth.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KCNH5 elisa kit

Reference Product	PubMed Publications
KCNH1 elisa kit	>12 publications with KCNH5 and KCNH1
KCNB2 elisa kit	>1 publications with KCNH5 and KCNB2
KCNQ3 elisa kit	>1 publications with KCNH5 and KCNQ3

Pathways associated with KCNH5 elisa kit

Products by Pathway	Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Potassium Channels Pathway antibodies	Potassium Channels Pathway Diagram
Voltage Gated Potassium Channels Pathway antibodies	Voltage Gated Potassium Channels Pathway Diagram

Diseases associated with KCNH5 elisa kit

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>3 publications with KCNH5 and Brain Diseases
Fibrosis Antibodies	>1 publications with KCNH5 and Fibrosis
Carcinoma, Squamous Cell Antibodies	>1 publications with KCNH5 and Carcinoma, Squamous Cell
Colonic Neoplasms Antibodies	>1 publications with KCNH5 and Colonic Neoplasms
Liver Neoplasms Antibodies	>1 publications with KCNH5 and Liver Neoplasms
Intestinal Neoplasms Antibodies	>1 publications with KCNH5 and Intestinal Neoplasms
Liver Diseases Antibodies	>1 publications with KCNH5 and Liver Diseases

Organs/Tissues associated with KCNH5 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>13 publications with KCNH5 and Brain
Nerve Antibodies	>1 publications with KCNH5 and Nerve
Testis Antibodies	>1 publications with KCNH5 and Testis