Norepinephrine (NE) ELISA Kit for Horse

Name: Horse NE ELISA Kit; Norepinephrine; MyBioSource
Brand: MyBioSource
SKU: MBS281259
Price: 545 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS281259

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate NE in samples. An antibody specific for NE has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyNE present is bound by the… More details

$545 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Norepinephrine, ELISA Kit

Full Product Name

Horse Norepinephrine (NE) ELISA Kit

Product Gene Name

NE elisa kit

Species Reactivity

Horse

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Horse NE. No significant cross-reactivity or interference between Horse NE and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

57,370 Da

OMIM

gene 604715

3D Structure

ModBase 3D Structure for P23975

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NE purchase

MBS281259 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Norepinephrine, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NE. The ELISA analytical biochemical technique of the MBS281259 kit is based on NE antibody-NE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for NE. It may not necessarily be applicable to this product.

NCBI GI #

1143479

NCBI GeneID

6530

NCBI Accession #

CAA62566.1

UniProt Primary Accession #

P23975

UniProt Secondary Accession #

Q96KH8; B2R707; B4DX48

UniProt Related Accession #

P23975

NCBI Official Full Name

norepinephrine transporter

NCBI Official Synonym Full Names

solute carrier family 6 (neurotransmitter transporter), member 2

NCBI Official Symbol

SLC6A2

NCBI Official Synonym Symbols

NET; NAT1; NET1; SLC6A5

UniProt Protein Name

Sodium-dependent noradrenaline transporter

UniProt Synonym Protein Names

Norepinephrine transporter; NET; Solute carrier family 6 member 2

Protein Family

Sodium-dependent noradrenaline transporter

UniProt Gene Name

SLC6A2

UniProt Synonym Gene Names

NAT1; NET1; SLC6A5; NET

UniProt Entry Name

SC6A2_HUMAN

NCBI Protein Information

sodium-dependent noradrenaline transporter; norepinephrine transporter; neurotransmitter transporter; solute carrier family 6 member 5; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

NCBI Summary for NE

This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]

UniProt Comments for NE

SLC6A2: Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. Defects in SLC6A2 are a cause of orthostatic intolerance (OI). OI is a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.

Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family

Chromosomal Location of Human Ortholog: 16q12.2

Cellular Component: neuron projection; cell surface; membrane; integral to plasma membrane; plasma membrane; lipid raft

Molecular Function: protein binding; monoamine transmembrane transporter activity; beta-tubulin binding; alpha-tubulin binding; norephinephrine:sodium symporter activity

Biological Process: response to drug; synaptic transmission; norepinephrine transport; transport; neurotransmitter transport; monoamine transport; response to pain; transmembrane transport

Disease: Orthostatic Intolerance

Research Articles on NE

1. We suggest that the oncogenic properties of CML cells are probably due to deregulated expression of NET1 as a result of altered expression of miR-22.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NE elisa kit

Reference Product	PubMed Publications
SLC18A2 elisa kit	>13 publications with NE and SLC18A2
PICK1 elisa kit	>2 publications with NE and PICK1
STX1A elisa kit	>1 publications with NE and STX1A

Pathways associated with NE elisa kit

Products by Pathway	Pathway Diagram
Monoamine Transport Pathway antibodies	Monoamine Transport Pathway Diagram
Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies	Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies	Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with NE elisa kit

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>122 publications with NE and Mental Disorders
Attention Deficit Disorder with Hyperactivity Antibodies	>50 publications with NE and Attention Deficit Disorder with Hyperactivity
Nervous System Diseases Antibodies	>49 publications with NE and Nervous System Diseases
Cardiovascular Diseases Antibodies	>47 publications with NE and Cardiovascular Diseases
Depressive Disorder Antibodies	>38 publications with NE and Depressive Disorder
Heart Diseases Antibodies	>32 publications with NE and Heart Diseases
Brain Diseases Antibodies	>30 publications with NE and Brain Diseases
Hypertension Antibodies	>26 publications with NE and Hypertension
Disease Models, Animal Antibodies	>25 publications with NE and Disease Models, Animal
Tachycardia Antibodies	>17 publications with NE and Tachycardia

Organs/Tissues associated with NE elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>277 publications with NE and Brain
Nerve Antibodies	>267 publications with NE and Nerve
Muscle Antibodies	>44 publications with NE and Muscle
Kidney Antibodies	>28 publications with NE and Kidney
Placenta Antibodies	>18 publications with NE and Placenta
Intestine Antibodies	>2 publications with NE and Intestine
Testis Antibodies	>2 publications with NE and Testis
Prostate Antibodies	>1 publications with NE and Prostate