Galectin 3 (GAL3) ELISA Kit for Canine

Name: Canine GAL3 ELISA Kit; Galectin 3; MyBioSource
Brand: MyBioSource
SKU: MBS028126
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS028126

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of GAL3 (hereafter termed "analyte") in undiluted original… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Galectin 3 (GAL3), ELISA Kit

Full Product Name

Canine Galectin 3 ELISA Kit

Product Gene Name

GAL3 elisa kit

Species Reactivity

Canine

Assay Type

Quantitative Sandwich

Detection Range

1.25ng/ml-40ng/ml

Sensitivity

0.1ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

26,152 Da

Chromosome Location

Chromosome: 14; NC_000014.8 (55595935..55612148). Location: 14q22.3

OMIM

153619

3D Structure

ModBase 3D Structure for P17931

Other Notes

Small volumes of GAL3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAL3 purchase

MBS028126 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Galectin 3 (GAL3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GAL3. The ELISA analytical biochemical technique of the MBS028126 kit is based on GAL3 antibody-GAL3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GAL3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GAL3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GAL3. It may not necessarily be applicable to this product.

NCBI GI #

294345475

NCBI GeneID

3958

NCBI Accession #

NP_001170859.1

UniProt Primary Accession #

P17931

UniProt Secondary Accession #

Q16005; Q6IBA7; Q96J47; B2RC38

UniProt Related Accession #

P17931

GenBank Nucleotide #

NM_001177388.1

NCBI Official Full Name

galectin-3 isoform 2

NCBI Official Synonym Full Names

lectin, galactoside-binding, soluble, 3

NCBI Official Symbol

LGALS3

NCBI Official Synonym Symbols

L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2

UniProt Protein Name

Galectin-3

UniProt Synonym Protein Names

35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen

Protein Family

Galectin-3-binding protein

UniProt Gene Name

LGALS3

UniProt Synonym Gene Names

MAC2; Gal-3; CBP 35; GALBP

UniProt Entry Name

LEG3_HUMAN

NCBI Protein Information

galectin-3; lectin L-29; 35 kDa lectin; MAC-2 antigen; IgE-binding protein; laminin-binding protein; galactose-specific lectin 3; carbohydrate-binding protein 35

NCBI Summary for GAL3

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]

UniProt Comments for GAL3

Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages.

Protein type: Cell surface; Extracellular matrix; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q22.3

Cellular Component: spliceosome; extracellular matrix; extracellular space; proteinaceous extracellular matrix; membrane; cytoplasm; mitochondrial inner membrane; plasma membrane; immunological synapse; nucleus; external side of plasma membrane

Molecular Function: protein binding; laminin binding; IgE binding; carbohydrate binding; chemoattractant activity

Biological Process: neutrophil chemotaxis; monocyte chemotaxis; extracellular matrix organization and biogenesis; positive chemotaxis; epithelial cell differentiation; negative regulation of endocytosis; RNA splicing; regulation of T cell proliferation; eosinophil chemotaxis; innate immune response; negative regulation of T cell receptor signaling pathway; mRNA processing; skeletal development; macrophage chemotaxis

Research Articles on GAL3

1. Galectin-3 correlated significantly with certain biomarkers involved in extracellular matrix turnover, although no definite relationship was identified with LV remodeling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GAL3 elisa kit

Reference Product	PubMed Publications
LGALS3BP elisa kit	>34 publications with GAL3 and LGALS3BP
EGFR elisa kit	>25 publications with GAL3 and EGFR
MUC1 elisa kit	>21 publications with GAL3 and MUC1
KRAS elisa kit	>8 publications with GAL3 and KRAS
GEMIN4 elisa kit	>5 publications with GAL3 and GEMIN4
PRKCSH elisa kit	>2 publications with GAL3 and PRKCSH
NRAS elisa kit	>2 publications with GAL3 and NRAS
HRAS elisa kit	>2 publications with GAL3 and HRAS
DDOST elisa kit	>2 publications with GAL3 and DDOST
SUFU elisa kit	>1 publications with GAL3 and SUFU

Pathways associated with GAL3 elisa kit

Products by Pathway	Pathway Diagram
AGE/RAGE Pathway antibodies	AGE/RAGE Pathway Diagram
Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies	Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies	Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Spinal Cord Injury Pathway antibodies	Spinal Cord Injury Pathway Diagram

Diseases associated with GAL3 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>795 publications with GAL3 and Neoplasms
Carcinoma Antibodies	>486 publications with GAL3 and Carcinoma
Adenocarcinoma Antibodies	>208 publications with GAL3 and Adenocarcinoma
Inflammation Antibodies	>196 publications with GAL3 and Inflammation
Adenoma Antibodies	>131 publications with GAL3 and Adenoma
Neoplasm Metastasis Antibodies	>129 publications with GAL3 and Neoplasm Metastasis
Disease Models, Animal Antibodies	>124 publications with GAL3 and Disease Models, Animal
Nervous System Diseases Antibodies	>122 publications with GAL3 and Nervous System Diseases
Breast Neoplasms Antibodies	>101 publications with GAL3 and Breast Neoplasms
Brain Diseases Antibodies	>92 publications with GAL3 and Brain Diseases

Organs/Tissues associated with GAL3 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>468 publications with GAL3 and Blood
Thyroid Antibodies	>269 publications with GAL3 and Thyroid
Vascular Antibodies	>138 publications with GAL3 and Vascular
Brain Antibodies	>115 publications with GAL3 and Brain
Lung Antibodies	>101 publications with GAL3 and Lung
Bone Antibodies	>100 publications with GAL3 and Bone
Heart Antibodies	>97 publications with GAL3 and Heart
Liver Antibodies	>97 publications with GAL3 and Liver
Kidney Antibodies	>95 publications with GAL3 and Kidney
Skin Antibodies	>76 publications with GAL3 and Skin