Probable G-Protein Coupled Receptor 37 (GPR37) ELISA Kit for Human

Name: Human GPR37 ELISA Kit; Probable G-Protein Coupled Receptor 37; MyBioSource
Brand: MyBioSource
SKU: MBS281358
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS281358

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate GPR37 in samples. An antibody specific for GPR37 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyGPR37 present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Probable G-protein coupled receptor 37 (GPR37), ELISA Kit

Full Product Name

Human Probable G-protein coupled receptor 37 (GPR37) ELISA Kit

Product Gene Name

GPR37 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Human GPR37. No significant cross-reactivity or interference between Human GPR37 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

67,114 Da

3D Structure

ModBase 3D Structure for O15354

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GPR37 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR37 purchase

MBS281358 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Probable G-protein coupled receptor 37 (GPR37) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GPR37. The ELISA analytical biochemical technique of the MBS281358 kit is based on GPR37 antibody-GPR37 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GPR37 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GPR37. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GPR37. It may not necessarily be applicable to this product.

NCBI GI #

4885323

NCBI GeneID

2861

NCBI Accession #

NP_005293.1

UniProt Primary Accession #

O15354

UniProt Secondary Accession #

O00348; O14768; Q8TD39; A4D0Y6

UniProt Related Accession #

O15354

GenBank Nucleotide #

NM_005302.4

NCBI Official Full Name

prosaposin receptor GPR37

NCBI Official Synonym Full Names

G protein-coupled receptor 37

NCBI Official Symbol

GPR37

NCBI Official Synonym Symbols

PAELR; EDNRBL; hET(B)R-LP

UniProt Protein Name

Prosaposin receptor GPR37

UniProt Synonym Protein Names

Endothelin B receptor-like protein 1; ETBR-LP-1; G-protein coupled receptor 37; Parkin-associated endothelin receptor-like receptor; PAELR

Protein Family

Prosaposin receptor

UniProt Gene Name

GPR37

UniProt Synonym Gene Names

ETBR-LP-1; PAELR

NCBI Protein Information

prosaposin receptor GPR37

NCBI Summary for GPR37

This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012]

UniProt Comments for GPR37

GPR37: Orphan receptor. May have a unique functional role in the central nervous system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 7q31.33

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral component of plasma membrane; plasma membrane; receptor complex; ubiquitin ligase complex

Molecular Function: G-protein coupled receptor activity; heat shock protein binding; Hsp70 protein binding; peptide binding; peptide receptor activity, G-protein coupled; protein binding; ubiquitin protein ligase binding

Biological Process: dopamine biosynthetic process; G-protein coupled receptor signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; locomotion during locomotory behavior; positive regulation of dopamine metabolic process; positive regulation of MAPK cascade

Research Articles on GPR37

1. REG4 promotes peritoneal metastasis of gastric cancer through GPR37 and triggers a positive feedback loop.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GPR37 elisa kit

Reference Product	PubMed Publications
PARK2 elisa kit	>1 publications with GPR37 and PARK2

Pathways associated with GPR37 elisa kit

Products by Pathway	Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Parkin-Ubiquitin Proteasomal System Pathway antibodies	Parkin-Ubiquitin Proteasomal System Pathway Diagram
Parkinson's Disease Pathway antibodies	Parkinson's Disease Pathway Diagram
Parkinsons Disease Pathway antibodies	Parkinsons Disease Pathway Diagram

Diseases associated with GPR37 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>18 publications with GPR37 and Nervous System Diseases
Drug Toxicity Antibodies	>5 publications with GPR37 and Drug Toxicity
Nerve Degeneration Antibodies	>3 publications with GPR37 and Nerve Degeneration
Disease Models, Animal Antibodies	>2 publications with GPR37 and Disease Models, Animal
Fibrosis Antibodies	>1 publications with GPR37 and Fibrosis

Organs/Tissues associated with GPR37 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>21 publications with GPR37 and Brain
Nerve Antibodies	>15 publications with GPR37 and Nerve
Embryonic Tissue Antibodies	>2 publications with GPR37 and Embryonic Tissue
Liver Antibodies	>1 publications with GPR37 and Liver
Placenta Antibodies	>1 publications with GPR37 and Placenta
Testis Antibodies	>1 publications with GPR37 and Testis