Potassium Channel Subfamily K Member 1 (KCNK1) ELISA Kit for Human

Name: Human KCNK1 ELISA Kit; Potassium Channel Subfamily K Member 1; MyBioSource
Brand: MyBioSource
SKU: MBS281926
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS281926

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate KCNK1 in samples. An antibody specific for KCNK1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyKCNK1 present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Potassium channel subfamily K member 1 (KCNK1), ELISA Kit

Full Product Name

Human Potassium channel subfamily K member 1 (KCNK1) ELISA Kit

Product Gene Name

KCNK1 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Human KCNK1. No significant cross-reactivity or interference between Human KCNK1 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

38,143 Da

OMIM

U33632 mRNA

3D Structure

ModBase 3D Structure for O00180

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KCNK1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNK1 purchase

MBS281926 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Potassium channel subfamily K member 1 (KCNK1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KCNK1. The ELISA analytical biochemical technique of the MBS281926 kit is based on KCNK1 antibody-KCNK1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KCNK1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KCNK1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for KCNK1. It may not necessarily be applicable to this product.

NCBI GI #

4504847

NCBI GeneID

3775

NCBI Accession #

NP_002236.1

UniProt Primary Accession #

O00180

UniProt Secondary Accession #

Q13307; Q5T5E8

UniProt Related Accession #

O00180

GenBank Nucleotide #

NM_002245.3

NCBI Official Full Name

potassium channel subfamily K member 1

NCBI Official Synonym Full Names

potassium two pore domain channel subfamily K member 1

NCBI Official Symbol

KCNK1

NCBI Official Synonym Symbols

DPK; HOHO; K2P1; KCNO1; TWIK1; K2p1.1; TWIK-1

UniProt Protein Name

Potassium channel subfamily K member 1

UniProt Synonym Protein Names

Inward rectifying potassium channel protein TWIK-1

Protein Family

Potassium channel subfamily

UniProt Gene Name

KCNK1

NCBI Protein Information

potassium channel subfamily K member 1

NCBI Summary for KCNK1

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

UniProt Comments for KCNK1

KCNK1: Weakly inward rectifying potassium channel. Homodimer (Potential). Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q42.2

Cellular Component: apical plasma membrane; brush border membrane; cell junction; dendrite; integral component of membrane; integral component of plasma membrane; intracellular membrane-bound organelle; perikaryon; plasma membrane; recycling endosome; synapse; voltage-gated potassium channel complex

Molecular Function: inward rectifier potassium channel activity; potassium channel activity; potassium ion leak channel activity; sodium channel activity; voltage-gated potassium channel activity

Biological Process: potassium ion transport; regulation of resting membrane potential; response to nicotine; stabilization of membrane potential

Research Articles on KCNK1

1. Dynamics of the TWIK-1 Channel

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with KCNK1 elisa kit

Products by Pathway	Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Potassium Channels Pathway antibodies	Potassium Channels Pathway Diagram
Tandem Of Pore Domain In A Weak Inwardly Rectifying K+ Channels (TWIK) Pathway antibodies	Tandem Of Pore Domain In A Weak Inwardly Rectifying K+ Channels (TWIK) Pathway Diagram
Tandem Pore Domain Potassium Channels Pathway antibodies	Tandem Pore Domain Potassium Channels Pathway Diagram

Diseases associated with KCNK1 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>6 publications with KCNK1 and Cardiovascular Diseases
Heart Diseases Antibodies	>4 publications with KCNK1 and Heart Diseases
Neoplasms Antibodies	>3 publications with KCNK1 and Neoplasms
Brain Diseases Antibodies	>2 publications with KCNK1 and Brain Diseases
Pain Antibodies	>1 publications with KCNK1 and Pain
Heart Failure Antibodies	>1 publications with KCNK1 and Heart Failure
Hypertension Antibodies	>1 publications with KCNK1 and Hypertension
Abnormalities, Drug-Induced Antibodies	>1 publications with KCNK1 and Abnormalities, Drug-Induced
Carcinoma, Hepatocellular Antibodies	>1 publications with KCNK1 and Carcinoma, Hepatocellular
Hyperplasia Antibodies	>1 publications with KCNK1 and Hyperplasia

Organs/Tissues associated with KCNK1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>19 publications with KCNK1 and Brain
Nerve Antibodies	>13 publications with KCNK1 and Nerve
Heart Antibodies	>12 publications with KCNK1 and Heart
Kidney Antibodies	>9 publications with KCNK1 and Kidney
Lung Antibodies	>5 publications with KCNK1 and Lung
Ear Antibodies	>5 publications with KCNK1 and Ear
Pancreas Antibodies	>3 publications with KCNK1 and Pancreas
Blood Antibodies	>3 publications with KCNK1 and Blood
Adrenal Gland Antibodies	>2 publications with KCNK1 and Adrenal Gland
Uterus Antibodies	>2 publications with KCNK1 and Uterus