Polypeptide N-Acetylgalactosaminyltransferase 2 (GALNT2) ELISA Kit for Human

Name: Human GALNT2 ELISA Kit; Polypeptide N-Acetylgalactosaminyltransferase 2; MyBioSource
Brand: MyBioSource
SKU: MBS282327
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS282327

Intended Uses: For the quantitative detection of Human Polypeptide N- acetylgalactosaminyl- transferase 2 (GALNT2) concentration in serum, plasma and other biological fluids.Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2), ELISA Kit

Full Product Name

Human Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) ELISA Kit

Product Gene Name

GALNT2 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma and other biological fluids

Detection Range

0.31 ng/mL - 20 ng/mL

Sensitivity

0.1 ng/mL

Specificity

This assay has high sensitivity and excellent specificity for detection of Human GALNT2. No significant cross-reactivity or interference between Human GALNT2 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Inter-assay Precision

Inter-assay Precision (Precision between assays) Three samples of known concentration were tested in forty separate assays to assess inter-assay precision. CV (%) = SD/meanX100. Inter-Assay: CV<12%

Intra-assay Precision

Intra-assay Precision (Precision within an assay) Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision. Intra-Assay: CV<8%

Molecular Weight

30,256 Da

OMIM

X85019 mRNA

3D Structure

ModBase 3D Structure for Q10471

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GALNT2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GALNT2 purchase

MBS282327 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GALNT2. The ELISA analytical biochemical technique of the MBS282327 kit is based on GALNT2 antibody-GALNT2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GALNT2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GALNT2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GALNT2. It may not necessarily be applicable to this product.

NCBI GI #

630044879

NCBI GeneID

2590

NCBI Accession #

NP_001278795.1

UniProt Primary Accession #

Q10471

UniProt Secondary Accession #

Q9NPY4; A8K1Y3; B7Z8V8; C5HU00

UniProt Related Accession #

Q10471

GenBank Nucleotide #

NM_001291866.1

NCBI Official Full Name

polypeptide N-acetylgalactosaminyltransferase 2 isoform 2

NCBI Official Synonym Full Names

polypeptide N-acetylgalactosaminyltransferase 2

NCBI Official Symbol

GALNT2

NCBI Official Synonym Symbols

GalNAc-T2

UniProt Protein Name

Polypeptide N-acetylgalactosaminyltransferase 2

UniProt Synonym Protein Names

Polypeptide GalNAc transferase 2; GalNAc-T2; pp-GaNTase 2

Protein Family

Polypeptide N-acetylgalactosaminyltransferase

UniProt Gene Name

GALNT2

UniProt Synonym Gene Names

GalNAc-T2; pp-GaNTase 2

NCBI Protein Information

polypeptide N-acetylgalactosaminyltransferase 2

NCBI Summary for GALNT2

This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

UniProt Comments for GALNT2

GALNT2: an enzyme that catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. A single-pass type II membrane protein that localizes to the Golgi apparatus membrane. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b.

Protein type: EC 2.4.1.41; Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 1q42.13

Cellular Component: endoplasmic reticulum membrane; extracellular exosome; Golgi apparatus; Golgi membrane; Golgi stack; integral to Golgi membrane; membrane; perinuclear region of cytoplasm

Molecular Function: carbohydrate binding; manganese ion binding; polypeptide N-acetylgalactosaminyltransferase activity; protein binding

Biological Process: immunoglobulin biosynthetic process; O-glycan processing; protein O-linked glycosylation; protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine

Research Articles on GALNT2

1. Our results indicate that GALNT2 suppresses the malignant potential of gastric adenocarcinoma cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GALNT2 elisa kit

Reference Product	PubMed Publications
MUC1 elisa kit	>1 publications with GALNT2 and MUC1

Pathways associated with GALNT2 elisa kit

Products by Pathway	Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Mucin Type O-Glycan Biosynthesis Pathway antibodies	Mucin Type O-Glycan Biosynthesis Pathway Diagram
Mucin Type O-Glycan Biosynthesis Pathway antibodies	Mucin Type O-Glycan Biosynthesis Pathway Diagram
O-glycan Biosynthesis, Mucin Type Core Pathway antibodies	O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
O-glycan Biosynthesis, Mucin Type Core Pathway antibodies	O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
O-linked Glycosylation Of Mucins Pathway antibodies	O-linked Glycosylation Of Mucins Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram

Diseases associated with GALNT2 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>7 publications with GALNT2 and Cardiovascular Diseases
Hyperlipidemias Antibodies	>3 publications with GALNT2 and Hyperlipidemias
Carcinoma Antibodies	>2 publications with GALNT2 and Carcinoma
Neoplasms Antibodies	>2 publications with GALNT2 and Neoplasms
Arteriosclerosis Antibodies	>2 publications with GALNT2 and Arteriosclerosis
Lung Neoplasms Antibodies	>1 publications with GALNT2 and Lung Neoplasms
Adenocarcinoma Antibodies	>1 publications with GALNT2 and Adenocarcinoma
Liver Diseases Antibodies	>1 publications with GALNT2 and Liver Diseases
Hyperlipoproteinemias Antibodies	>1 publications with GALNT2 and Hyperlipoproteinemias
Liver Neoplasms Antibodies	>1 publications with GALNT2 and Liver Neoplasms

Organs/Tissues associated with GALNT2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>17 publications with GALNT2 and Blood
Vascular Antibodies	>5 publications with GALNT2 and Vascular
Heart Antibodies	>5 publications with GALNT2 and Heart
Liver Antibodies	>3 publications with GALNT2 and Liver
Intestine Antibodies	>1 publications with GALNT2 and Intestine
Lung Antibodies	>1 publications with GALNT2 and Lung
Brain Antibodies	>1 publications with GALNT2 and Brain