Human ADCYAP1R1 ELISA Kit – Cat# MBS282612

Pituitary Adenylate Cyclase-Activating Polypeptide Type 1 Receptor (ADCYAP1R1) ELISA Kit for Human

Name: Human ADCYAP1R1 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS282612
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS282612

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate ADCYAP1R1 in samples. An antibody specific for ADCYAP1R1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyADCYAP1R1 present is… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1), ELISA Kit

Full Product Name

Human Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) ELISA Kit

Product Gene Name

ADCYAP1R1 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Human ADCYAP1R1. No significant cross-reactivity or interference between Human ADCYAP1R1 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

46,957 Da

OMIM

D17516 mRNA

3D Structure

ModBase 3D Structure for P41586

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ADCYAP1R1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADCYAP1R1 purchase

MBS282612 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADCYAP1R1. The ELISA analytical biochemical technique of the MBS282612 kit is based on ADCYAP1R1 antibody-ADCYAP1R1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADCYAP1R1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADCYAP1R1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ADCYAP1R1. It may not necessarily be applicable to this product.

NCBI GI #

29171759

NCBI GeneID

117

NCBI Accession #

NP_001109.2

UniProt Primary Accession #

P41586

UniProt Secondary Accession #

Q17S10; A8K1Y1; B7ZLA7; B8ZZK3

UniProt Related Accession #

P41586

GenBank Nucleotide #

NM_001118.4

NCBI Official Full Name

pituitary adenylate cyclase-activating polypeptide type I receptor isoform 3

NCBI Official Synonym Full Names

ADCYAP receptor type I

NCBI Official Symbol

ADCYAP1R1

NCBI Official Synonym Symbols

PAC1; PAC1R; PACAPR; PACAPRI

UniProt Protein Name

Pituitary adenylate cyclase-activating polypeptide type I receptor

Protein Family

Pituitary adenylate cyclase-activating polypeptide type I receptor

UniProt Gene Name

ADCYAP1R1

UniProt Synonym Gene Names

PACAP type I receptor; PACAP-R-1; PACAP-R1

NCBI Protein Information

pituitary adenylate cyclase-activating polypeptide type I receptor

NCBI Summary for ADCYAP1R1

This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]

UniProt Comments for ADCYAP1R1

ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: bicellular tight junction; caveola; cell surface; endosome; integral component of plasma membrane; neuron projection; plasma membrane; receptor complex; rough endoplasmic reticulum

Molecular Function: adenylate cyclase binding; ADP-ribosylation factor binding; neuropeptide binding; protein binding; receptor activity; vasoactive intestinal polypeptide receptor activity

Biological Process: activation of phospholipase C activity; cAMP-mediated signaling; cell differentiation; cell surface receptor signaling pathway; development of primary female sexual characteristics; G-protein coupled receptor signaling pathway; multicellular organismal response to stress; positive regulation of cAMP biosynthetic process; positive regulation of small GTPase mediated signal transduction; response to drug; response to estradiol; response to ethanol; spermatogenesis

Research Articles on ADCYAP1R1

1. These findings lead to a model in which E2 induces the expression of ADCYAP1R1 through binding of ERalpha at the ERE as an adaptive response to stress. Inhibition of E2/ERalpha binding to the ERE containing the rs2267735 risk allele results in reduced expression of ADCYAP1R1, diminishing estrogen regulation as an adaptive stress response and increasing risk for PTSD.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ADCYAP1R1 elisa kit

Reference Product	PubMed Publications
ADCYAP1 elisa kit	>104 publications with ADCYAP1R1 and ADCYAP1
CRH elisa kit	>2 publications with ADCYAP1R1 and CRH
GHRH elisa kit	>2 publications with ADCYAP1R1 and GHRH
POMC elisa kit	>1 publications with ADCYAP1R1 and POMC

Pathways associated with ADCYAP1R1 elisa kit

Products by Pathway	Pathway Diagram
Activation Of TRKA Receptors Pathway antibodies	Activation Of TRKA Receptors Pathway Diagram
Circadian Entrainment Pathway antibodies	Circadian Entrainment Pathway Diagram
Circadian Entrainment Pathway antibodies	Circadian Entrainment Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class B Secretin-like Pathway antibodies	GPCRs, Class B Secretin-like Pathway Diagram

Diseases associated with ADCYAP1R1 elisa kit

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>6 publications with ADCYAP1R1 and Breast Neoplasms
Inflammation Antibodies	>5 publications with ADCYAP1R1 and Inflammation
Kidney Diseases Antibodies	>3 publications with ADCYAP1R1 and Kidney Diseases
Disease Models, Animal Antibodies	>2 publications with ADCYAP1R1 and Disease Models, Animal
Learning Disorders Antibodies	>2 publications with ADCYAP1R1 and Learning Disorders
Hyperplasia Antibodies	>2 publications with ADCYAP1R1 and Hyperplasia
Brain Injuries Antibodies	>2 publications with ADCYAP1R1 and Brain Injuries
Liver Neoplasms, Experimental Antibodies	>2 publications with ADCYAP1R1 and Liver Neoplasms, Experimental
Liver Diseases Antibodies	>2 publications with ADCYAP1R1 and Liver Diseases
Hypertrophy Antibodies	>2 publications with ADCYAP1R1 and Hypertrophy

Organs/Tissues associated with ADCYAP1R1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>76 publications with ADCYAP1R1 and Brain
Nerve Antibodies	>28 publications with ADCYAP1R1 and Nerve
Pituitary Gland Antibodies	>26 publications with ADCYAP1R1 and Pituitary Gland
Blood Antibodies	>15 publications with ADCYAP1R1 and Blood
Ganglia Antibodies	>14 publications with ADCYAP1R1 and Ganglia
Muscle Antibodies	>12 publications with ADCYAP1R1 and Muscle
Adrenal Gland Antibodies	>11 publications with ADCYAP1R1 and Adrenal Gland
Lung Antibodies	>10 publications with ADCYAP1R1 and Lung
Kidney Antibodies	>6 publications with ADCYAP1R1 and Kidney
Intestine Antibodies	>5 publications with ADCYAP1R1 and Intestine