• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Vitronectin (VTN) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS283425

Intended Uses: For the quantitative detection of Human Vitronectin (VTN) concentration in serum, plasma and other biological fluids.Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate VTN in Human serum, plasma. An antibody… More details

$545 / 48 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Vitronectin (VTN), ELISA Kit
Full Product Name
Human Vitronectin (VTN) ELISA Kit
Product Gene Name
VTN elisa kit
Species Reactivity
Human
Samples
serum, plasma and other biological fluids
Detection Range
1.56 ng/mL - 100 ng/mL
Sensitivity
1 ng/mL (mean of 6 independent assays).
Specificity
This assay has high sensitivity and excellent specificity for detection of Human VTN. No significant cross-reactivity or interference between Human VTN and analogues was observed.
Preparation and Storage
Store at 2-8 degree C.
Inter-assay Precision
Inter-assay Precision (Precision between assays) Three samples of known concentration were tested in forty separate assays to assess inter-assay precision. CV (%) = SD/meanX100. Inter-Assay: CV<12%
Intra-assay Precision
Intra-assay Precision (Precision within an assay) Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision. Intra-Assay: CV<8%
Molecular Weight
54,306 Da
OMIM
X03168 mRNA
3D Structure
ModBase 3D Structure for P04004
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of VTN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VTN purchase

MBS283425 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Vitronectin (VTN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VTN. The ELISA analytical biochemical technique of the MBS283425 kit is based on VTN antibody-VTN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VTN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VTN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for VTN. It may not necessarily be applicable to this product.

NCBI GI #
88853069
NCBI GeneID
7448
NCBI Accession #
NP_000629.3
UniProt Primary Accession #
P04004
UniProt Secondary Accession #
P01141; Q9BSH7; B2R7G0
UniProt Related Accession #
P04004
GenBank Nucleotide #
NM_000638.3
NCBI Official Full Name
vitronectin
NCBI Official Synonym Full Names
vitronectin
NCBI Official Symbol
VTN
NCBI Official Synonym Symbols
VN; V75; VNT
UniProt Protein Name
Vitronectin
UniProt Synonym Protein Names
S-protein; Serum-spreading factor; V75
Protein Family
Vitronectin
UniProt Gene Name
VTN
UniProt Synonym Gene Names
VN
NCBI Protein Information
vitronectin

NCBI Summary for VTN

The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for VTN

VTN: Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: basement membrane; blood microparticle; endoplasmic reticulum; extracellular exosome; extracellular matrix; extracellular region; extracellular space; Golgi lumen; intracellular membrane-bound organelle

Molecular Function: collagen binding; extracellular matrix binding; heparin binding; identical protein binding; integrin binding; polysaccharide binding; protein binding; scavenger receptor activity

Biological Process: cell adhesion; cell adhesion mediated by integrin; cell-matrix adhesion; endodermal cell differentiation; extracellular matrix organization; immune response; negative regulation of blood coagulation; negative regulation of endopeptidase activity; oligodendrocyte differentiation; positive regulation of cell-substrate adhesion; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein binding; positive regulation of receptor-mediated endocytosis; positive regulation of smooth muscle cell migration; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of wound healing; protein polymerization; receptor-mediated endocytosis; regulation of complement activation
Show more

Research Articles on VTN

1. Additionally, the authors utilized vitroenctin-derived peptides to map the minimal Rickettsia conorii Adr1/human vitronectin interaction to the C-terminal region of vitronectin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with VTN elisa kit

 Reference Product  PubMed Publications
 SERPINE1 elisa kit  >5 publications with VTN and SERPINE1
 PLAUR elisa kit  >3 publications with VTN and PLAUR
 TNFRSF11B elisa kit  >1 publications with VTN and TNFRSF11B
 TGFB1 elisa kit  >1 publications with VTN and TGFB1
 ITGB3 elisa kit  >1 publications with VTN and ITGB3
 ITGA8 elisa kit  >1 publications with VTN and ITGA8

Pathways associated with VTN elisa kit

 Products by Pathway  Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Inflammatory Response Pathway antibodies  Inflammatory Response Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram

Diseases associated with VTN elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3 publications with VTN and Cardiovascular Diseases
 Kidney Diseases Antibodies  >2 publications with VTN and Kidney Diseases
 Heart Diseases Antibodies  >2 publications with VTN and Heart Diseases
 Drug Toxicity Antibodies  >2 publications with VTN and Drug Toxicity
 Weight Loss Antibodies  >2 publications with VTN and Weight Loss
 Nervous System Diseases Antibodies  >1 publications with VTN and Nervous System Diseases
 Fibrosis Antibodies  >1 publications with VTN and Fibrosis
 Proteinuria Antibodies  >1 publications with VTN and Proteinuria
 Hypertension Antibodies  >1 publications with VTN and Hypertension
 Atherosclerosis Antibodies  >1 publications with VTN and Atherosclerosis

Organs/Tissues associated with VTN elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with VTN and Brain
 Blood Antibodies  >8 publications with VTN and Blood
 Heart Antibodies  >5 publications with VTN and Heart
 Lung Antibodies  >4 publications with VTN and Lung
 Kidney Antibodies  >3 publications with VTN and Kidney
 Eye Antibodies  >2 publications with VTN and Eye
 Placenta Antibodies  >2 publications with VTN and Placenta
 Pancreas Antibodies  >1 publications with VTN and Pancreas
 Embryonic Tissue Antibodies  >1 publications with VTN and Embryonic Tissue
 Uterus Antibodies  >1 publications with VTN and Uterus
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000