Glomulin (GLMN) ELISA Kit for Mouse

Name: Mouse GLMN ELISA Kit; Glomulin; MyBioSource
Brand: MyBioSource
SKU: MBS284034
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS284034

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate GLMN in samples. An antibody specific for GLMN has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyGLMN present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Glomulin (GLMN), ELISA Kit

Full Product Name

Mouse Glomulin (GLMN) ELISA Kit

Product Gene Name

GLMN elisa kit

Product Synonym Names

FAP; FAP48; FAP68; FKBPAP; GLML; GVM; VMGLOM; FK506-binding protein-associated protein|glomulin

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Mouse GLMN. No significant cross-reactivity or interference between Mouse GLMN and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

67,756 Da

3D Structure

ModBase 3D Structure for Q8BZM1

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of GLMN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLMN purchase

MBS284034 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glomulin (GLMN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GLMN. The ELISA analytical biochemical technique of the MBS284034 kit is based on GLMN antibody-GLMN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GLMN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GLMN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for GLMN. It may not necessarily be applicable to this product.

NCBI GI #

239985599

NCBI GeneID

170823

NCBI Accession #

NP_001155210.1

UniProt Primary Accession #

Q8BZM1

UniProt Secondary Accession #

Q3TFR5; Q99LB8

UniProt Related Accession #

Q8BZM1

GenBank Nucleotide #

NM_001161738.1

NCBI Official Full Name

glomulin isoform a

NCBI Official Synonym Full Names

glomulin, FKBP associated protein

NCBI Official Symbol

Glmn

NCBI Official Synonym Symbols

Fap48; Fap68; AW227515; 9330160J16Rik

UniProt Protein Name

Glomulin

UniProt Synonym Protein Names

FK506-binding protein-associated protein; FAP; FKBP-associated protein

Protein Family

Glomulin

UniProt Gene Name

Glmn

UniProt Synonym Gene Names

Fap48; FAP

NCBI Protein Information

glomulin

UniProt Comments for GLMN

GLMN: Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 production. Defects in GLMN are the cause of glomuvenous malformations (GVMs). GVMs are characterized by the presence of smooth-muscle-like glomus cells in the media surrounding distended vascular lumens. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 5|5 E5

Cellular Component: Cul2-RING ubiquitin ligase complex; cullin-RING ubiquitin ligase complex; cytoplasm

Molecular Function: hepatocyte growth factor receptor binding; protein binding; receptor binding; ubiquitin protein ligase binding; ubiquitin-protein transferase inhibitor activity

Biological Process: cell surface receptor signaling pathway; muscle cell differentiation; negative regulation of cell proliferation; negative regulation of T cell proliferation; neural tube closure; positive regulation of cytokine secretion; positive regulation of interleukin-2 biosynthetic process; positive regulation of phosphorylation; regulation of gene expression, epigenetic; regulation of proteasomal ubiquitin-dependent protein catabolic process; vasculogenesis

Research Articles on GLMN

1. Results indicate a bacterial adaptation that hijacks inflammasome activation via interactions between IpaH7.8 E3 ubiquitin ligase and glomulin (GLMN).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with GLMN elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>9 publications with GLMN and Skin
Connective Tissue Antibodies	>1 publications with GLMN and Connective Tissue
Embryonic Tissue Antibodies	>1 publications with GLMN and Embryonic Tissue