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Urotensin-2 (UTS2) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS284146

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate UTS2 in samples. An antibody specific for UTS2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyUTS2 present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Urotensin-2 (UTS2), ELISA Kit
Full Product Name
Mouse Urotensin-2 (UTS2) ELISA Kit
Product Gene Name
UTS2 elisa kit
Product Synonym Names
PRO1068; U-II; UCN2; UII;
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, Plasma, Other biological fluids
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse UTS2. No significant cross-reactivity or interference between Mouse UTS2 and analogues was observed.
Preparation and Storage
Store at 2-8 degree C.
Molecular Weight
13,625 Da
3D Structure
ModBase 3D Structure for Q9QZQ3
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UTS2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UTS2 purchase

MBS284146 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Urotensin-2 (UTS2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing UTS2. The ELISA analytical biochemical technique of the MBS284146 kit is based on UTS2 antibody-UTS2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect UTS2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, UTS2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for UTS2. It may not necessarily be applicable to this product.

NCBI GI #
6755931
NCBI GeneID
24111
NCBI Accession #
NP_036040.1
UniProt Primary Accession #
Q9QZQ3
UniProt Related Accession #
Q9QZQ3
GenBank Nucleotide #
NM_011910.2
NCBI Official Full Name
urotensin-2 preproprotein
NCBI Official Synonym Full Names
urotensin 2
NCBI Official Symbol
Uts2
NCBI Official Synonym Symbols
UII; Ucn2; prepro-UII
UniProt Protein Name
Urotensin-2
UniProt Synonym Protein Names
Urotensin II; U-II; UII
Protein Family
Urotensin-2 receptor
UniProt Gene Name
Uts2
UniProt Synonym Gene Names
Ucn2; U-II; UII
NCBI Protein Information
urotensin-2

NCBI Summary for UTS2

This gene encodes a member of the urotensin family of peptide hormones. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone before secretion into the plasma. Mice lacking the encoded protein have a significantly decreased low density lipoprotein cholesterol profile and hepatic steatosis that is consistent with decreased hepatocyte de novo cholesterol synthesis and apolipoprotein B secretion. [provided by RefSeq, Sep 2016]
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UniProt Comments for UTS2

UTS2: Highly potent vasoconstrictor. Belongs to the urotensin-2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4|4 E2

Cellular Component: extracellular region; extracellular space

Molecular Function: hormone activity

Biological Process: elevation of cytosolic calcium ion concentration; negative regulation of blood pressure; negative regulation of glomerular filtration; negative regulation of heart rate; negative regulation of insulin secretion; positive regulation of angiogenesis; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of collagen biosynthetic process; positive regulation of fibroblast proliferation; positive regulation of heart rate; positive regulation of synaptic transmission, cholinergic; regulation of blood pressure
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Research Articles on UTS2

1. Urotensin II plays a role in the pathogenesis and priming of acute liver failure by triggering an inflammatory cascade and driving the early release of TNF-alpha and Il1beta.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with UTS2 elisa kit

 Products by Pathway  Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with UTS2 elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5 publications with UTS2 and Cardiovascular Diseases
 Hypertension Antibodies  >4 publications with UTS2 and Hypertension
 Myocardial Ischemia Antibodies  >3 publications with UTS2 and Myocardial Ischemia
 Pregnancy Complications Antibodies  >1 publications with UTS2 and Pregnancy Complications
 Autoimmune Diseases Antibodies  >1 publications with UTS2 and Autoimmune Diseases
 Brain Diseases Antibodies  >1 publications with UTS2 and Brain Diseases
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