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Urokinase-Type Plasminogen Activator Receptor (PLAUR/uPAR) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS284254

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate PLAUR/uPAR in samples. An antibody specific for PLAUR/uPAR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPLAUR/uPAR present is… More details

$545 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Urokinase-type Plasminogen Activator Receptor (PLAUR/uPAR), ELISA Kit
Full Product Name
Mouse Urokinase-type Plasminogen Activator Receptor (PLAUR/uPAR) ELISA Kit
Product Gene Name
PLAUR/uPAR elisa kit
Product Synonym Names
CD87; UPAR; URKR; monocyte activation antigen Mo3|u-plasminogen activator receptor form 2
Species Reactivity
Mouse
Assay Type
Sandwich
Samples
Serum, Plasma, Other biological fluids
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse PLAUR/uPAR. No significant cross-reactivity or interference between Mouse PLAUR/uPAR and analogues was observed.
Preparation and Storage
Store at 2-8 degree C.
Molecular Weight
24,619 Da
3D Structure
ModBase 3D Structure for P35456
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PLAUR/uPAR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLAUR/uPAR purchase

MBS284254 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Urokinase-type Plasminogen Activator Receptor (PLAUR/uPAR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLAUR/uPAR. The ELISA analytical biochemical technique of the MBS284254 kit is based on PLAUR/uPAR antibody-PLAUR/uPAR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLAUR/uPAR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLAUR/uPAR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PLAUR/uPAR. It may not necessarily be applicable to this product.

NCBI GI #
7242179
NCBI GeneID
18793
NCBI Accession #
NP_035243.1
UniProt Primary Accession #
P35456
UniProt Secondary Accession #
P35457
GenBank Nucleotide #
NM_011113.4
NCBI Official Full Name
urokinase plasminogen activator surface receptor
UniProt Protein Name
Urokinase plasminogen activator surface receptor
UniProt Synonym Protein Names
CD_antigen: CD87
Protein Family
C-type mannose receptor
UniProt Gene Name
Plaur
UniProt Synonym Gene Names
U-PAR; uPAR

UniProt Comments for PLAUR/uPAR

uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Receptor, misc.

Chromosomal Location of Human Ortholog: 7|7 A3

Cellular Component: cell surface; extracellular region; focal adhesion; integral component of plasma membrane; membrane; plasma membrane

Molecular Function: enzyme binding; protein binding; protein domain specific binding; receptor binding; U-plasminogen activator receptor activity

Biological Process: mesenchymal cell differentiation; negative regulation of apoptosis; positive regulation of DNA binding; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of protein phosphorylation; regulation of proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PLAUR/uPAR elisa kit

 Products by Pathway  Pathway Diagram
 Attachment Of GPI Anchor To UPAR Pathway antibodies  Attachment Of GPI Anchor To UPAR Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 PodNet: Protein-protein Interactions In The Podocyte Pathway antibodies  PodNet: Protein-protein Interactions In The Podocyte Pathway Diagram
 Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies  Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with PLAUR/uPAR elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >805 publications with PLAUR/uPAR and Neoplasms
 Carcinoma Antibodies  >309 publications with PLAUR/uPAR and Carcinoma
 Neoplasm Invasiveness Antibodies  >259 publications with PLAUR/uPAR and Neoplasm Invasiveness
 Neoplasm Metastasis Antibodies  >228 publications with PLAUR/uPAR and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >162 publications with PLAUR/uPAR and Breast Neoplasms
 Inflammation Antibodies  >107 publications with PLAUR/uPAR and Inflammation
 Lung Diseases Antibodies  >89 publications with PLAUR/uPAR and Lung Diseases
 Nervous System Diseases Antibodies  >80 publications with PLAUR/uPAR and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >80 publications with PLAUR/uPAR and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >75 publications with PLAUR/uPAR and Lung Neoplasms

Organs/Tissues associated with PLAUR/uPAR elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >144 publications with PLAUR/uPAR and Lung
 Liver Antibodies  >82 publications with PLAUR/uPAR and Liver
 Embryonic Tissue Antibodies  >79 publications with PLAUR/uPAR and Embryonic Tissue
 Kidney Antibodies  >67 publications with PLAUR/uPAR and Kidney
 Skin Antibodies  >63 publications with PLAUR/uPAR and Skin
 Bone Marrow Antibodies  >43 publications with PLAUR/uPAR and Bone Marrow
 Connective Tissue Antibodies  >31 publications with PLAUR/uPAR and Connective Tissue
 Spleen Antibodies  >16 publications with PLAUR/uPAR and Spleen
 Thyroid Antibodies  >12 publications with PLAUR/uPAR and Thyroid
 Mammary Gland Antibodies  >7 publications with PLAUR/uPAR and Mammary Gland
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