Rabbit FKBP1A ELISA Kit – Cat# MBS285093

Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A (FKBP1A) ELISA Kit for Rabbit

Name: Rabbit FKBP1A ELISA Kit; Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A; MyBioSource
Brand: MyBioSource
SKU: MBS285093
Price: 545 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS285093

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate FKBP1A in samples. An antibody specific for FKBP1A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyFKBP1A present is bound by… More details

$545 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Peptidyl-prolyl cis-trans isomerase FKBP1A, ELISA Kit

Full Product Name

Rabbit Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) ELISA Kit

Product Gene Name

FKBP1A elisa kit

Product Synonym Names

RP11-314N13.2; FKBP-12; FKBP1; FKBP12; FKBP12C; PKC12; PKCI2; PPIASE; FK506 binding protein12|FK506-binding protein 1|FK506-binding protein 12|FK506-binding protein 1A (12kD)|FK506-binding protein

Species Reactivity

Rabbit

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Rabbit FKBP1A. No significant cross-reactivity or interference between Rabbit FKBP1A and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

11,951 Da

3D Structure

ModBase 3D Structure for P62943

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FKBP1A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FKBP1A purchase

MBS285093 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Peptidyl-prolyl cis-trans isomerase FKBP1A, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FKBP1A. The ELISA analytical biochemical technique of the MBS285093 kit is based on FKBP1A antibody-FKBP1A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FKBP1A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FKBP1A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FKBP1A. It may not necessarily be applicable to this product.

NCBI GI #

283837823

NCBI GeneID

100328942

NCBI Accession #

NP_001164597.1

UniProt Primary Accession #

P62943

UniProt Secondary Accession #

P20071; Q9H103; Q9H566

UniProt Related Accession #

P62943

GenBank Nucleotide #

NM_001171126.1

NCBI Official Full Name

peptidyl-prolyl cis-trans isomerase FKBP1A

NCBI Official Symbol

FKBP1A

NCBI Official Synonym Symbols

FKBP1; FKBP12; FKBP-12; FKBP-1A; Rotamase

UniProt Protein Name

Peptidyl-prolyl cis-trans isomerase FKBP1A

UniProt Synonym Protein Names

12 kDa FK506-binding protein; 12 kDa FKBP; FKBP-12; Calstabin-1; FK506-binding protein 1A; FKBP-1A; Immunophilin FKBP12; Rotamase

Protein Family

Peptidyl-prolyl cis-trans isomerase

UniProt Gene Name

FKBP1A

UniProt Synonym Gene Names

FKBP1; FKBP12; PPIase FKBP1A; 12 kDa FKBP; FKBP-12; FKBP-1A

NCBI Protein Information

peptidyl-prolyl cis-trans isomerase FKBP1A

UniProt Comments for FKBP1A

Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ().

Research Articles on FKBP1A

1. Data indicate that S107 increased FKBP12 binding to RyR1 in sarcoplasmic reticulum vesicles in the presence of reduced glutathione and the NO-donor NOC12.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with FKBP1A elisa kit

Disease Name	Pubmed Publications
Muscular Diseases Antibodies	>3 publications with FKBP1A and Muscular Diseases
Neoplasms Antibodies	>3 publications with FKBP1A and Neoplasms
Inflammation Antibodies	>2 publications with FKBP1A and Inflammation
Nervous System Diseases Antibodies	>2 publications with FKBP1A and Nervous System Diseases
Hypertension Antibodies	>1 publications with FKBP1A and Hypertension
Acute Kidney Injury Antibodies	>1 publications with FKBP1A and Acute Kidney Injury
Urinary Bladder Diseases Antibodies	>1 publications with FKBP1A and Urinary Bladder Diseases
Breast Neoplasms Antibodies	>1 publications with FKBP1A and Breast Neoplasms
Brain Diseases Antibodies	>1 publications with FKBP1A and Brain Diseases
Neoplasms, Experimental Antibodies	>1 publications with FKBP1A and Neoplasms, Experimental