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Urotensin-2 (UTS2R) ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS285405

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate UTS2R in samples. An antibody specific for UTS2R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyUTS2R present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Urotensin-2 (UTS2R), ELISA Kit
Full Product Name
Rat Urotensin-2 receptor (UTS2R) ELISA Kit
Product Gene Name
UTS2R elisa kit
Product Synonym Names
GPR14; UTR; UTR2; G protein-coupled receptor 14
Species Reactivity
Rat
Assay Type
Sandwich
Samples
Serum, Plasma, Other biological fluids
Specificity
This assay has high sensitivity and excellent specificity for detection of Rat UTS2R. No significant cross-reactivity or interference between Rat UTS2R and analogues was observed.
Preparation and Storage
Store at 2-8 degree C.
Molecular Weight
42,707 Da
3D Structure
ModBase 3D Structure for P49684
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UTS2R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UTS2R purchase

MBS285405 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Urotensin-2 (UTS2R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing UTS2R. The ELISA analytical biochemical technique of the MBS285405 kit is based on UTS2R antibody-UTS2R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect UTS2R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, UTS2R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for UTS2R. It may not necessarily be applicable to this product.

NCBI GI #
10120496
NCBI GeneID
57305
NCBI Accession #
NP_065412.1
UniProt Primary Accession #
P49684
UniProt Secondary Accession #
P48041
UniProt Related Accession #
P49684
GenBank Nucleotide #
NM_020537.1
NCBI Official Full Name
urotensin-2 receptor
NCBI Official Synonym Full Names
urotensin 2 receptor
NCBI Official Symbol
Uts2r
NCBI Official Synonym Symbols
Senr; Gpr14; UR-2-R
UniProt Protein Name
Urotensin-2 receptor
UniProt Synonym Protein Names
G-protein coupled receptor 14; G-protein coupled sensory epithelial neuropeptide-like receptor; SENR; Urotensin II receptor; UR-II-R
Protein Family
Urotensin-2 receptor
UniProt Gene Name
Uts2r
UniProt Synonym Gene Names
Gpr14; Senr; UR-2-R; SENR; UR-II-R
NCBI Protein Information
urotensin-2 receptor

NCBI Summary for UTS2R

G protein-coupled receptor isolated from retinal and taste cells [RGD, Feb 2006]

UniProt Comments for UTS2R

UTS2R: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 10q32.3

Cellular Component: early endosome; integral component of plasma membrane; plasma membrane; recycling endosome

Molecular Function: urotensin II receptor activity

Biological Process: elevation of cytosolic calcium ion concentration; negative regulation of blood pressure; negative regulation of glomerular filtration; neuropeptide signaling pathway; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of angiogenesis; positive regulation of blood pressure; positive regulation of cell growth; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of fibroblast proliferation; positive regulation of vasoconstriction; response to drug
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Research Articles on UTS2R

1. This study investigated possible role of U-II and its receptor expression in inflammation by using UTR agonist and antagonist in carrageenan induced acute inflammation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with UTS2R elisa kit

 Reference Product  PubMed Publications
 Uts2d elisa kit  >11 publications with UTS2R and Uts2d
 Uts2 elisa kit  >4 publications with UTS2R and Uts2
 Avp elisa kit  >1 publications with UTS2R and Avp

Pathways associated with UTS2R elisa kit

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with UTS2R elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >69 publications with UTS2R and Cardiovascular Diseases
 Kidney Diseases Antibodies  >20 publications with UTS2R and Kidney Diseases
 Diabetes Mellitus Antibodies  >17 publications with UTS2R and Diabetes Mellitus
 Hypertrophy Antibodies  >14 publications with UTS2R and Hypertrophy
 Cardiomegaly Antibodies  >11 publications with UTS2R and Cardiomegaly
 Inflammation Antibodies  >10 publications with UTS2R and Inflammation
 Carcinoma Antibodies  >8 publications with UTS2R and Carcinoma
 Liver Diseases Antibodies  >8 publications with UTS2R and Liver Diseases
 Fibrosis Antibodies  >8 publications with UTS2R and Fibrosis
 Lung Diseases Antibodies  >6 publications with UTS2R and Lung Diseases
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