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Uv Excision Repair Protein RAD23 Homolog B (RAD23B) ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS285661

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate RAD23B in samples. An antibody specific for RAD23B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyRAD23B present is bound by… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UV excision repair protein RAD23 homolog B (RAD23B), ELISA Kit
Full Product Name
Rat UV excision repair protein RAD23 homolog B (RAD23B) ELISA Kit
Product Gene Name
RAD23B elisa kit
Product Synonym Names
RP11-131A5.1; HHR23B; HR23B; P58; RAD23; yeast homolog of; B|UV excision repair protein RAD23 homolog B|XP-C repair complementing complex 58 kDa|XP-C repair complementing protein
Species Reactivity
Rat
Assay Type
Sandwich
Samples
Serum, Plasma, Other biological fluids
Specificity
This assay has high sensitivity and excellent specificity for detection of Rat RAD23B. No significant cross-reactivity or interference between Rat RAD23B and analogues was observed.
Preparation and Storage
Store at 2-8 degree C.
Molecular Weight
43,497 Da
3D Structure
ModBase 3D Structure for Q4KMA2
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RAD23B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAD23B purchase

MBS285661 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the UV excision repair protein RAD23 homolog B (RAD23B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RAD23B. The ELISA analytical biochemical technique of the MBS285661 kit is based on RAD23B antibody-RAD23B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RAD23B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RAD23B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for RAD23B. It may not necessarily be applicable to this product.

NCBI GI #
70778952
NCBI GeneID
298012
NCBI Accession #
NP_001020446.1
UniProt Primary Accession #
Q4KMA2
UniProt Secondary Accession #
Q0D2G8; Q5CZZ8; Q6IRD5
UniProt Related Accession #
Q4KMA2
GenBank Nucleotide #
NM_001025275.1
NCBI Official Full Name
UV excision repair protein RAD23 homolog B
NCBI Official Synonym Full Names
RAD23 homolog B, nucleotide excision repair protein
NCBI Official Symbol
Rad23b
UniProt Protein Name
UV excision repair protein RAD23 homolog B
Protein Family
Ubiquitin receptor
UniProt Gene Name
Rad23b
NCBI Protein Information
UV excision repair protein RAD23 homolog B

UniProt Comments for RAD23B

RAD23B: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum- associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Belongs to the RAD23 family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q24

Cellular Component: cytosol; nucleoplasm; proteasome complex

Molecular Function: damaged DNA binding; polyubiquitin modification-dependent protein binding

Biological Process: cellular response to DNA damage stimulus; embryonic organ development; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; proteasomal ubiquitin-dependent protein catabolic process; regulation of proteasomal ubiquitin-dependent protein catabolic process; spermatogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with RAD23B elisa kit

 Products by Pathway  Pathway Diagram
 DNA Damage Recognition In GG-NER Pathway antibodies  DNA Damage Recognition In GG-NER Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Dual Incision Reaction In GG-NER Pathway antibodies  Dual Incision Reaction In GG-NER Pathway Diagram
 Formation Of Incision Complex In GG-NER Pathway antibodies  Formation Of Incision Complex In GG-NER Pathway Diagram
 Global Genomic NER (GG-NER) Pathway antibodies  Global Genomic NER (GG-NER) Pathway Diagram
 Nucleotide Excision Repair Pathway antibodies  Nucleotide Excision Repair Pathway Diagram
 Nucleotide Excision Repair Pathway antibodies  Nucleotide Excision Repair Pathway Diagram
 Nucleotide Excision Repair Pathway antibodies  Nucleotide Excision Repair Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram

Diseases associated with RAD23B elisa kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >34 publications with RAD23B and Neoplasms
 Skin Diseases Antibodies  >13 publications with RAD23B and Skin Diseases
 Precancerous Conditions Antibodies  >11 publications with RAD23B and Precancerous Conditions
 Carcinoma Antibodies  >6 publications with RAD23B and Carcinoma
 Ataxia Antibodies  >5 publications with RAD23B and Ataxia
 Head and Neck Neoplasms Antibodies  >5 publications with RAD23B and Head and Neck Neoplasms
 Nervous System Diseases Antibodies  >5 publications with RAD23B and Nervous System Diseases
 Brain Diseases Antibodies  >4 publications with RAD23B and Brain Diseases
 Lung Neoplasms Antibodies  >4 publications with RAD23B and Lung Neoplasms
 Liver Neoplasms Antibodies  >3 publications with RAD23B and Liver Neoplasms

Organs/Tissues associated with RAD23B elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with RAD23B and Lung
 Liver Antibodies  >3 publications with RAD23B and Liver
 Brain Antibodies  >3 publications with RAD23B and Brain
 Prostate Antibodies  >2 publications with RAD23B and Prostate
 Kidney Antibodies  >1 publications with RAD23B and Kidney
 Connective Tissue Antibodies  >1 publications with RAD23B and Connective Tissue
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