SNAI1 ELISA Kit for Human

Name: Human SNAI1 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS285693
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS285693

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate SNAI1 in samples. An antibody specific for SNAI1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySNAI1 present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

SNAI1, ELISA Kit

Full Product Name

Human Zinc finger protein SNAI1 (SNAI1) ELISA Kit

Product Gene Name

SNAI1 elisa kit

Product Synonym Names

SLUGH2; SNA; SNAH; dJ710H13.1; snail 1 homolog|snail 1 zinc finger protein|snail 1; zinc finger protein

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Human SNAI1. No significant cross-reactivity or interference between Human SNAI1 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

29,083 Da

OMIM

AF125377 mRNA

3D Structure

ModBase 3D Structure for O95863

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SNAI1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNAI1 purchase

MBS285693 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SNAI1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SNAI1. The ELISA analytical biochemical technique of the MBS285693 kit is based on SNAI1 antibody-SNAI1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SNAI1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SNAI1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for SNAI1. It may not necessarily be applicable to this product.

NCBI GI #

18765741

NCBI GeneID

6615

NCBI Accession #

NP_005976.2

UniProt Primary Accession #

O95863

UniProt Secondary Accession #

Q9P113; Q9UBP7; Q9UHH7; B2R842

UniProt Related Accession #

O95863

GenBank Nucleotide #

NM_005985.3

NCBI Official Full Name

zinc finger protein SNAI1

NCBI Official Synonym Full Names

snail family transcriptional repressor 1

NCBI Official Symbol

SNAI1

NCBI Official Synonym Symbols

SNA; SNAH; SNAIL; SLUGH2; SNAIL1; dJ710H13.1

UniProt Protein Name

Zinc finger protein SNAI1

UniProt Synonym Protein Names

Protein snail homolog 1; Protein sna

Protein Family

Protein snail

UniProt Gene Name

SNAI1

UniProt Synonym Gene Names

SNAH; Protein sna

NCBI Protein Information

zinc finger protein SNAI1

NCBI Summary for SNAI1

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]

UniProt Comments for SNAI1

Snail1: a protein of the C2H2-type zinc-finger family that regulates transcription. Involved in embryonic mesoderm formation. Plays a role in the epithelial to mesenchymal transition (EMT). EMT is characterized by decreased levels of the epithelial markers E-cadherin and alpha- and beta-catenin, and increased cellular migration and expression of the mesenchymal markers fibronectin, vimentin, N-cadherin and smooth muscle alpha-actin.E Snail binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. NF-kappaB binds and regulates the snail promoter and is critical for EMT, and inhibition of NF-kappaB activity lowered snail levels and morphologically reversed the EMT.

Protein type: C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 20q13.13

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: kinase binding; metal ion binding; protein binding

Biological Process: cell migration; epithelial to mesenchymal transition; epithelial to mesenchymal transition involved in endocardial cushion formation; hair follicle morphogenesis; mesoderm formation; negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of transcription from RNA polymerase II promoter; negative regulation of vitamin D biosynthetic process; osteoblast differentiation; palate development; positive regulation of cell migration; positive regulation of epithelial to mesenchymal transition; positive regulation of transcription, DNA-templated; regulation of bicellular tight junction assembly

Research Articles on SNAI1

1. Snail-1 might play an important role in the progression of bladder cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SNAI1 elisa kit

Products by Pathway	Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Adherens Junction Pathway antibodies	Adherens Junction Pathway Diagram
Neural Crest Differentiation Pathway antibodies	Neural Crest Differentiation Pathway Diagram
Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway antibodies	Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway Diagram
Validated Targets Of C-MYC Transcriptional Activation Pathway antibodies	Validated Targets Of C-MYC Transcriptional Activation Pathway Diagram

Diseases associated with SNAI1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>71 publications with SNAI1 and Neoplasms
Neoplasm Invasiveness Antibodies	>27 publications with SNAI1 and Neoplasm Invasiveness
Breast Neoplasms Antibodies	>23 publications with SNAI1 and Breast Neoplasms
Neoplasm Metastasis Antibodies	>22 publications with SNAI1 and Neoplasm Metastasis
Lung Neoplasms Antibodies	>16 publications with SNAI1 and Lung Neoplasms
Lung Diseases Antibodies	>15 publications with SNAI1 and Lung Diseases
Disease Models, Animal Antibodies	>9 publications with SNAI1 and Disease Models, Animal
Carcinoma, Squamous Cell Antibodies	>9 publications with SNAI1 and Carcinoma, Squamous Cell
Cell Transformation, Neoplastic Antibodies	>7 publications with SNAI1 and Cell Transformation, Neoplastic
Melanoma Antibodies	>7 publications with SNAI1 and Melanoma

Organs/Tissues associated with SNAI1 elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>27 publications with SNAI1 and Lung
Embryonic Tissue Antibodies	>23 publications with SNAI1 and Embryonic Tissue
Bone Antibodies	>14 publications with SNAI1 and Bone
Skin Antibodies	>9 publications with SNAI1 and Skin
Vascular Antibodies	>9 publications with SNAI1 and Vascular
Brain Antibodies	>6 publications with SNAI1 and Brain
Blood Antibodies	>5 publications with SNAI1 and Blood
Pancreas Antibodies	>5 publications with SNAI1 and Pancreas
Kidney Antibodies	>4 publications with SNAI1 and Kidney
Intestine Antibodies	>3 publications with SNAI1 and Intestine