Myocyte-Specific Enhancer Factor 2c (MEF2C) ELISA Kit for Bovine

Name: Bovine MEF2C ELISA Kit; Myocyte-Specific Enhancer Factor 2c; MyBioSource
Brand: MyBioSource
SKU: MBS285789
Price: 545 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS285789

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate MEF2C in samples. An antibody specific for MEF2C has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMEF2C present is bound by the… More details

$545 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Myocyte-specific enhancer factor 2C (MEF2C), ELISA Kit

Full Product Name

Bovine Myocyte-specific enhancer factor 2C (MEF2C) ELISA Kit

Product Gene Name

MEF2C elisa kit

Product Synonym Names

MADS box transcription enhancer factor 2; polypeptide C (myocyte enhancer factor 2C)

Species Reactivity

Bovine

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Bovine MEF2C. No significant cross-reactivity or interference between Bovine MEF2C and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

47,844 Da

3D Structure

ModBase 3D Structure for Q2KIA0

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MEF2C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MEF2C purchase

MBS285789 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Myocyte-specific enhancer factor 2C (MEF2C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MEF2C. The ELISA analytical biochemical technique of the MBS285789 kit is based on MEF2C antibody-MEF2C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MEF2C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MEF2C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MEF2C. It may not necessarily be applicable to this product.

NCBI GI #

114052623

NCBI GeneID

512254

NCBI Accession #

NP_001039578.1

UniProt Primary Accession #

Q2KIA0

UniProt Related Accession #

Q2KIA0

GenBank Nucleotide #

NM_001046113.1

NCBI Official Full Name

myocyte-specific enhancer factor 2C

NCBI Official Synonym Full Names

myocyte enhancer factor 2C

NCBI Official Symbol

MEF2C

UniProt Protein Name

Myocyte-specific enhancer factor 2C

Protein Family

Myocyte-specific enhancer factor

UniProt Gene Name

MEF2C

NCBI Protein Information

myocyte-specific enhancer factor 2C

UniProt Comments for MEF2C

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture ().

Research Articles on MEF2C

1. The myocyte enhancer factor 2 family of MADS is highly expressed in cells of muscle lineage, where they have been proven to be important regulators of gene expression during the development of skeletal, cardiac and smooth muscle.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MEF2C elisa kit

Products by Pathway	Pathway Diagram
Activated TLR4 Signalling Pathway antibodies	Activated TLR4 Signalling Pathway Diagram
Delta-Notch Signaling Pathway antibodies	Delta-Notch Signaling Pathway Diagram
ERK/MAPK Targets Pathway antibodies	ERK/MAPK Targets Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
MAP Kinase Activation In TLR Cascade Pathway antibodies	MAP Kinase Activation In TLR Cascade Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Targets/ Nuclear Events Mediated By MAP Kinases Pathway antibodies	MAPK Targets/ Nuclear Events Mediated By MAP Kinases Pathway Diagram

Diseases associated with MEF2C elisa kit

Disease Name	Pubmed Publications
MENTAL RETARDATION, STEREOTYPIC MOVEMENTS, EPILEPSY, AND/OR CEREBRAL MALFORMATIONS Antibodies	>81615 publications with MEF2C and MENTAL RETARDATION, STEREOTYPIC MOVEMENTS, EPILEPSY, AND/OR CEREBRAL MALFORMATIONS
Nervous System Diseases Antibodies	>33 publications with MEF2C and Nervous System Diseases
Neoplasms Antibodies	>30 publications with MEF2C and Neoplasms
Heart Defects, Congenital Antibodies	>20 publications with MEF2C and Heart Defects, Congenital
Myocardial Infarction Antibodies	>17 publications with MEF2C and Myocardial Infarction
Brain Diseases Antibodies	>16 publications with MEF2C and Brain Diseases
Intellectual Disability Antibodies	>11 publications with MEF2C and Intellectual Disability
Cardiomegaly Antibodies	>10 publications with MEF2C and Cardiomegaly
Skin Diseases Antibodies	>10 publications with MEF2C and Skin Diseases
Fibrosis Antibodies	>10 publications with MEF2C and Fibrosis

Organs/Tissues associated with MEF2C elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>266 publications with MEF2C and Muscle
Brain Antibodies	>57 publications with MEF2C and Brain
Kidney Antibodies	>5 publications with MEF2C and Kidney
Intestine Antibodies	>1 publications with MEF2C and Intestine
Testis Antibodies	>1 publications with MEF2C and Testis