P2Y Purinoceptor 6 (P2RY6) ELISA Kit for Human

Name: Human P2RY6 ELISA Kit; P2Y Purinoceptor 6; MyBioSource
Brand: MyBioSource
SKU: MBS287974
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS287974

Intended Uses: For the quantitative detection of Human P2Y purinoceptor 6 (P2RY6) concentration in serum, plasma and other biological fluids.Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate P2RY6 in Human serum, plasma. An… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

P2Y purinoceptor 6 (P2RY6), ELISA Kit

Full Product Name

Human P2Y purinoceptor 6 (P2RY6) ELISA Kit

Product Gene Name

P2RY6 elisa kit

Product Synonym Names

MGC15335; P2Y6; G-coupled nucleotide receptor; P2 purinoceptor; P2Y purinoceptor 6; P2Y6 receptor; pyrimidinergic receptor P2Y6

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma and other biological fluids

Detection Range

62.5 pg/mL - 4000 pg/mL

Sensitivity

31.25 pg/mL

Specificity

This assay has high sensitivity and excellent specificity for detection of Human P2RY6. No significant cross-reactivity or interference between Human P2RY6 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Inter-assay Precision

Inter-assay Precision (Precision between assays) Three samples of known concentration were tested in forty separate assays to assess inter-assay precision. CV (%) = SD/meanX100. Inter-Assay: CV<12%

Intra-assay Precision

Intra-assay Precision (Precision within an assay) Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision. Intra-Assay: CV<8%

Molecular Weight

36,429 Da

OMIM

X97058 mRNA

3D Structure

ModBase 3D Structure for Q15077

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of P2RY6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P2RY6 purchase

MBS287974 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the P2Y purinoceptor 6 (P2RY6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing P2RY6. The ELISA analytical biochemical technique of the MBS287974 kit is based on P2RY6 antibody-P2RY6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect P2RY6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, P2RY6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for P2RY6. It may not necessarily be applicable to this product.

NCBI GI #

469832283

NCBI GeneID

5031

NCBI Accession #

NP_001264133.1

UniProt Primary Accession #

Q15077

UniProt Secondary Accession #

Q15754

UniProt Related Accession #

Q15077

GenBank Nucleotide #

NM_001277204.1

NCBI Official Full Name

P2Y purinoceptor 6 isoform 1

NCBI Official Synonym Full Names

pyrimidinergic receptor P2Y6

NCBI Official Symbol

P2RY6

NCBI Official Synonym Symbols

P2Y6

UniProt Protein Name

P2Y purinoceptor 6

Protein Family

P2Y purinoceptor

UniProt Gene Name

P2RY6

UniProt Synonym Gene Names

P2Y6

NCBI Protein Information

P2Y purinoceptor 6

NCBI Summary for P2RY6

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013]

UniProt Comments for P2RY6

Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Research Articles on P2RY6

1. Expression levels of P2Y6 receptor were higher in Parkinson's disease patients compared to healthy controls.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with P2RY6 elisa kit

Reference Product	PubMed Publications
P2RY1 elisa kit	>2 publications with P2RY6 and P2RY1

Pathways associated with P2RY6 elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Nucleotide GPCRs Pathway antibodies	Nucleotide GPCRs Pathway Diagram
Nucleotide-like (purinergic) Receptors Pathway antibodies	Nucleotide-like (purinergic) Receptors Pathway Diagram

Diseases associated with P2RY6 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>5 publications with P2RY6 and Inflammation
Immune System Diseases Antibodies	>1 publications with P2RY6 and Immune System Diseases

Organs/Tissues associated with P2RY6 elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with P2RY6 and Lung