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Integrin Alpha-V (ITGAV) ELISA Kit for Chicken

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS288183

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to Integrin alpha-V. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated polyclonal antibody… More details

$490 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Integrin alpha-V (ITGAV), ELISA Kit
Full Product Name
Chicken Integrin alpha-V ELISA Kit
Product Gene Name
Species Reactivity
Chicken
Samples
Serum, Plasma, tissue homogenates and Cell culture supernates and Other biological fluids.
Detection Range
0.78 ng/ml -50.0 ng/ml.
Specificity
This assay recognizes recombinant and natural chicken Integrin alpha-V. No significant cross-reactivity or interference was observed.
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
114,389 Da
3D Structure
ModBase 3D Structure for P26008
Intended Uses
This immunoassay kit allows for the in vitro quantitative determination of chicken Integrin alpha-V concentrations in serum, Plasma, tissue homogenates and Cell culture supernates and Other biological fluids.

Typical Testing Data/Standard Curve (for reference only) of ITGAV elisa kit

Chicken ITGAV ELISA Kit – Cat# MBS288183

Other Notes

Small volumes of ITGAV elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ITGAV purchase

MBS288183 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Integrin alpha-V (ITGAV) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITGAV. The ELISA analytical biochemical technique of the MBS288183 kit is based on ITGAV antibody-ITGAV antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITGAV antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITGAV. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ITGAV. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-V
NCBI Official Synonym Full Names
integrin, alpha V
NCBI Official Symbol
ITGAV
UniProt Protein Name
Integrin alpha-V
UniProt Synonym Protein Names
Vitronectin receptor subunit alpha
Protein Family
UniProt Gene Name
ITGAV
UniProt Entry Name
ITAV_CHICK
NCBI Protein Information
integrin alpha-V

UniProt Comments for ITGAV

The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGAV:ITGB3 and ITGAV:ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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