Baculoviral IAP Repeat-Containing Protein 1a (NAIP1) ELISA Kit for Mouse

Name: Mouse NAIP1 ELISA Kit; Baculoviral IAP Repeat-Containing Protein 1a; MyBioSource
Brand: MyBioSource
SKU: MBS288480
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS288480

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to Baculoviral IAP repeat-containing protein 1a. Standards or samples are then added to the appropriate microtiter plate wells with a… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Baculoviral IAP repeat-containing protein 1a (Naip1), ELISA Kit

Full Product Name

Mouse Baculoviral IAP repeat-containing protein 1a ELISA Kit

Product Gene Name

Naip1 elisa kit

Species Reactivity

Mouse

Assay Type

Sandwich

Detection Range

0.312-20 ng/ml

Sensitivity

0.156 ng/mL

Specificity

This assay recognizes recombinant and natural mouse Baculoviral IAP repeat-containing protein 1a. No significant cross-reactivity or interference was observed.

Preparation and Storage

For long term storage, please store the entire kit at -20 degree C.

Molecular Weight

158,724 Da

3D Structure

ModBase 3D Structure for Q9QWK5

Intra-Assay CV

<=6.2%

Inter-Assay CV

<=7.8%

Recovery

99%

Other Notes

Small volumes of Naip1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Naip1 purchase

MBS288480 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Baculoviral IAP repeat-containing protein 1a (Naip1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Naip1. The ELISA analytical biochemical technique of the MBS288480 kit is based on Naip1 antibody-Naip1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Naip1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Naip1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Naip1. It may not necessarily be applicable to this product.

NCBI GI #

114431262

NCBI GeneID

17940

NCBI Accession #

NP_032696.2

UniProt Primary Accession #

Q9QWK5

UniProt Secondary Accession #

Q9JIB5; Q9R017; A2RT89

UniProt Related Accession #

Q9QWK5

GenBank Nucleotide #

NM_008670.2

NCBI Official Full Name

baculoviral IAP repeat-containing protein 1a

NCBI Official Synonym Full Names

NLR family, apoptosis inhibitory protein 1

NCBI Official Symbol

Naip1

NCBI Official Synonym Symbols

Naip; Birc1a; D13Lsd1; AV364616; Naip-rs1

UniProt Protein Name

Baculoviral IAP repeat-containing protein 1a

UniProt Synonym Protein Names

Neuronal apoptosis inhibitory protein 1

Protein Family

Baculoviral IAP repeat-containing protein

UniProt Gene Name

Naip1

UniProt Synonym Gene Names

Birc1a; Naip

UniProt Entry Name

BIR1A_MOUSE

NCBI Protein Information

baculoviral IAP repeat-containing protein 1a

UniProt Comments for Naip1

BIRC1: Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasing the rate of auto proteolysis at 'Asp-330'. Acts as a mediator of neuronal survival in pathological conditions. Prevents motor- neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.

Cellular Component: basolateral plasma membrane; cell soma; cytoplasm; neuron projection; perikaryon

Molecular Function: ATP binding; caspase inhibitor activity; cysteine protease inhibitor activity; metal ion binding; nucleotide binding; protease inhibitor activity; ubiquitin-protein ligase activity

Biological Process: apoptosis; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of peptidase activity; regulation of signal transduction

Research Articles on Naip1

1. An epithelium-intrinsic defense axis recruits NAIP and the NLRC4 inflammasome to promote removal of epithelial cells compromised by pathogen invasion.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Naip1 elisa kit

Reference Product	PubMed Publications
Casp1 elisa kit	>6 publications with Naip1 and Casp1
Nlrc4 elisa kit	>5 publications with Naip1 and Nlrc4
Hpca elisa kit	>2 publications with Naip1 and Hpca
Casp9 elisa kit	>2 publications with Naip1 and Casp9
Bcl2 elisa kit	>1 publications with Naip1 and Bcl2

Pathways associated with Naip1 elisa kit

Products by Pathway	Pathway Diagram
Legionellosis Pathway antibodies	Legionellosis Pathway Diagram
Legionellosis Pathway antibodies	Legionellosis Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram

Diseases associated with Naip1 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>9 publications with Naip1 and Nervous System Diseases
Necrosis Antibodies	>5 publications with Naip1 and Necrosis
Hypertension Antibodies	>1 publications with Naip1 and Hypertension
Uterine Cervical Neoplasms Antibodies	>1 publications with Naip1 and Uterine Cervical Neoplasms
Vascular Diseases Antibodies	>1 publications with Naip1 and Vascular Diseases
Weight Loss Antibodies	>1 publications with Naip1 and Weight Loss
Cardiovascular Diseases Antibodies	>1 publications with Naip1 and Cardiovascular Diseases

Organs/Tissues associated with Naip1 elisa kit

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>3 publications with Naip1 and Intestine
Uterus Antibodies	>2 publications with Naip1 and Uterus
Ovary Antibodies	>1 publications with Naip1 and Ovary