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Arachidonate 5-Lipoxygenase (ALOX5) ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS288857

MBS288857 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Arachidonate 5-lipoxygenase (Alox5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Arachidonate 5-lipoxygenase (Alox5), ELISA Kit
Full Product Name
Rat Arachidonate 5-lipoxygenase ELISA Kit
Product Gene Name
Alox5 elisa kit
Product Synonym Names
Arachidonate 5-lipoxygenase; 5-LO; 5-lipoxygenase; Alox5; 1.13.11.34
Species Reactivity
Rat
Assay Type
Sandwich
Detection Range
0.156-10 ng/mL
Sensitivity
0.088 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
78,087 Da
3D Structure
ModBase 3D Structure for P12527
Intra-Assay CV
<=4.3%
Inter-Assay CV
<=9.2%
Recovery
99%

Typical Testing Data/Standard Curve (for reference only) of Alox5 elisa kit

Rat ALOX5 ELISA Kit – Cat# MBS288857

Other Notes

Small volumes of Alox5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Alox5. It may not necessarily be applicable to this product.

NCBI GI #
6978493
NCBI GeneID
25290
NCBI Accession #
NP_036954.1
UniProt Primary Accession #
P12527
UniProt Related Accession #
P12527
GenBank Nucleotide #
NM_012822.1
NCBI Official Full Name
arachidonate 5-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 5-lipoxygenase
NCBI Official Symbol
Alox5
NCBI Official Synonym Symbols
LOX5A
UniProt Protein Name
Arachidonate 5-lipoxygenase
Protein Family
Arachidonate 5-lipoxygenase
UniProt Gene Name
Alox5
UniProt Synonym Gene Names
5-LO; 5-lipoxygenase
UniProt Entry Name
LOX5_RAT
NCBI Protein Information
arachidonate 5-lipoxygenase

NCBI Summary for Alox5

catalyzes the conversion of arachidonate to leukotriene A4 in leukotriene metabolism [RGD, Feb 2006]

UniProt Comments for Alox5

5-LO: arachidonate 5-lipoxygenase. Arachidonic acid promotes its phosphorylation by p38 MAPK-regulated MAPKAP kinases. Upregulated in glioblastoma multiforme and colon, pancreatic and bladder cancer.

Protein type: EC 1.13.11.34; Lipid Metabolism - arachidonic acid; Nuclear envelope; Lipid Metabolism - linoleic acid; Oxidoreductase

Cellular Component: cytoplasm; cytosol; dendrite; extracellular space; nuclear envelope; nuclear envelope lumen; nuclear matrix; nuclear membrane; nucleus; sarcolemma

Molecular Function: arachidonate 5-lipoxygenase activity; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding

Biological Process: acute inflammatory response; arachidonic acid metabolic process; inflammatory response; leukotriene biosynthetic process; leukotriene metabolic process; leukotriene production during acute inflammatory response; lipoxygenase pathway; positive regulation of vasoconstriction; response to hyperoxia; response to nutrient; sensory perception of pain
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Research Articles on Alox5

1. Alox5 affects the osteogenic and adipogenic abilities of iPSCs in vivo and the effect of Cox2 inhibition in this system.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Alox5 elisa kit

 Reference Product  PubMed Publications
 Ptgs2 elisa kit  >300 publications with Alox5 and Ptgs2
 Alox5ap elisa kit  >211 publications with Alox5 and Alox5ap
 Ptgs1 elisa kit  >121 publications with Alox5 and Ptgs1
 Pla2g4a elisa kit  >62 publications with Alox5 and Pla2g4a
 Lta4h elisa kit  >33 publications with Alox5 and Lta4h
 Ltc4s elisa kit  >29 publications with Alox5 and Ltc4s
 Pla2g2a elisa kit  >1 publications with Alox5 and Pla2g2a

Pathways associated with Alox5 elisa kit

 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 Folic Acid Network Pathway antibodies  Folic Acid Network Pathway Diagram
 IL-5 Signaling Pathway antibodies  IL-5 Signaling Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram

Diseases associated with Alox5 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >643 publications with Alox5 and Inflammation
 Asthma Antibodies  >264 publications with Alox5 and Asthma
 Lung Diseases Antibodies  >248 publications with Alox5 and Lung Diseases
 Atherosclerosis Antibodies  >137 publications with Alox5 and Atherosclerosis
 Necrosis Antibodies  >128 publications with Alox5 and Necrosis
 Edema Antibodies  >99 publications with Alox5 and Edema
 Heart Diseases Antibodies  >64 publications with Alox5 and Heart Diseases
 Pain Antibodies  >49 publications with Alox5 and Pain
 Neoplasms, Experimental Antibodies  >47 publications with Alox5 and Neoplasms, Experimental
 Liver Diseases Antibodies  >45 publications with Alox5 and Liver Diseases

Organs/Tissues associated with Alox5 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >154 publications with Alox5 and Brain
 Connective Tissue Antibodies  >20 publications with Alox5 and Connective Tissue
 Testis Antibodies  >1 publications with Alox5 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with Alox5 and Uncharacterized Tissue
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