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C-C Chemokine Receptor Type 7 (CCR7) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS288944

MBS288944 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-C chemokine receptor type 7 (Ccr7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-C chemokine receptor type 7 (Ccr7), ELISA Kit
Full Product Name
Mouse C-C chemokine receptor type 7 ELISA Kit
Product Gene Name
Ccr7 elisa kit
Product Synonym Names
C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor
Species Reactivity
Mouse
Assay Type
Sandwich
Detection Range
15.6-1000 pg/mL
Sensitivity
7.8 pg/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
42,856 Da
3D Structure
ModBase 3D Structure for P47774
Intra-Assay CV
<=6.2%
Inter-Assay CV
<=7.8%
Recovery
94%

Typical Testing Data/Standard Curve (for reference only) of Ccr7 elisa kit

Mouse CCR7 ELISA Kit – Cat# MBS288944

Other Notes

Small volumes of Ccr7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccr7. It may not necessarily be applicable to this product.

NCBI GI #
678246450
NCBI GeneID
12775
NCBI Accession #
NP_001288642.1
UniProt Primary Accession #
P47774
UniProt Secondary Accession #
Q8CAS2
UniProt Related Accession #
P47774
GenBank Nucleotide #
NM_001301713.1
NCBI Official Full Name
C-C chemokine receptor type 7 isoform b
NCBI Official Synonym Full Names
chemokine (C-C motif) receptor 7
NCBI Official Symbol
Ccr7
NCBI Official Synonym Symbols
EBI1; CCR-7; CD197; Ebi1h; Cdw197; Cmkbr7; CC-CKR-7
UniProt Protein Name
C-C chemokine receptor type 7
UniProt Synonym Protein Names
Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; CD_antigen: CD197
Protein Family
C-C chemokine receptor
UniProt Gene Name
Ccr7
UniProt Synonym Gene Names
Cmkbr7; Ebi1; Ebi1h; C-C CKR-7; CC-CKR-7; CCR-7; EBI1; EBV-induced G-protein coupled receptor 1
UniProt Entry Name
CCR7_MOUSE
NCBI Protein Information
C-C chemokine receptor type 7

UniProt Comments for Ccr7

CCR7: Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; GPCR, family 1; Receptor, GPCR

Cellular Component: cell surface; external side of plasma membrane; integral to membrane; intracellular; membrane; plasma membrane

Molecular Function: C-C chemokine receptor activity; chemokine receptor activity; G-protein coupled receptor activity; protein binding; signal transducer activity

Biological Process: actin cytoskeleton organization and biogenesis; activation of JNK activity; chemotaxis; establishment of T cell polarity; G-protein coupled receptor protein signaling pathway; homeostasis of number of cells; immune response; inflammatory response; lymph node development; lymphocyte chemotaxis across high endothelial venule; myeloid dendritic cell chemotaxis; negative thymic T cell selection; positive regulation of dendritic cell antigen processing and presentation; positive regulation of filopodium formation; positive regulation of GTPase activity; positive regulation of humoral immune response; positive regulation of hypersensitivity; positive regulation of interleukin-1 beta secretion; positive regulation of interleukin-12 production; positive regulation of phagocytosis; positive regulation of receptor-mediated endocytosis; positive regulation of T cell proliferation; positive regulation of T cell receptor signaling pathway; positive regulation of T-helper 1 cell differentiation; positive regulation of tumor necrosis factor production; regulation of interferon-gamma production; regulation of interleukin-1 beta secretion; regulation of tolerance induction to self antigen; response to lipopolysaccharide; signal transduction
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Research Articles on Ccr7

1. mucosal draining lymph nodes express CCR7, which has a role in trafficking of RORgamma innate lymphoid cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ccr7 elisa kit

 Reference Product  PubMed Publications
 Ccl19 elisa kit  >482 publications with Ccr7 and Ccl19
 Cxcl12 elisa kit  >168 publications with Ccr7 and Cxcl12
 Cxcl13 elisa kit  >56 publications with Ccr7 and Cxcl13
 Ccl17 elisa kit  >28 publications with Ccr7 and Ccl17
 TCA4 elisa kit  >8 publications with Ccr7 and TCA4

Pathways associated with Ccr7 elisa kit

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram

Diseases associated with Ccr7 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >421 publications with Ccr7 and Inflammation
 Necrosis Antibodies  >250 publications with Ccr7 and Necrosis
 Disease Models, Animal Antibodies  >158 publications with Ccr7 and Disease Models, Animal
 Lung Diseases Antibodies  >140 publications with Ccr7 and Lung Diseases
 Hypersensitivity Antibodies  >113 publications with Ccr7 and Hypersensitivity
 Liver Diseases Antibodies  >79 publications with Ccr7 and Liver Diseases
 Neoplasms, Experimental Antibodies  >64 publications with Ccr7 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >52 publications with Ccr7 and Breast Neoplasms
 Fibrosis Antibodies  >47 publications with Ccr7 and Fibrosis
 Atherosclerosis Antibodies  >46 publications with Ccr7 and Atherosclerosis

Organs/Tissues associated with Ccr7 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >832 publications with Ccr7 and Lymph Node
 Bone Marrow Antibodies  >270 publications with Ccr7 and Bone Marrow
 Skin Antibodies  >253 publications with Ccr7 and Skin
 Spleen Antibodies  >183 publications with Ccr7 and Spleen
 Liver Antibodies  >128 publications with Ccr7 and Liver
 Thymus Antibodies  >114 publications with Ccr7 and Thymus
 Embryonic Tissue Antibodies  >34 publications with Ccr7 and Embryonic Tissue
 Mammary Gland Antibodies  >2 publications with Ccr7 and Mammary Gland
 Uncharacterized Tissue Antibodies  >1 publications with Ccr7 and Uncharacterized Tissue
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