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Endothelin-1 Receptor (EDNRA) ELISA Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS288949

MBS288949 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Endothelin-1 receptor (Ednra) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Endothelin-1 receptor (Ednra), ELISA Kit
Full Product Name
Mouse Endothelin-1 receptor ELISA Kit
Product Gene Name
Ednra elisa kit
Product Synonym Names
Endothelin-1 receptor; Endothelin A receptor; ET-A; ET-AR; Ednra; Gpcr10
Species Reactivity
Mouse
Assay Type
Sandwich
Detection Range
0.156-10 ng/mL
Sensitivity
0.094 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
48,578 Da
3D Structure
ModBase 3D Structure for Q61614
Intra-Assay CV
<=6.9%
Inter-Assay CV
<=8.8%
Recovery
101%

Typical Testing Data/Standard Curve (for reference only) of Ednra elisa kit

Mouse EDNRA ELISA Kit – Cat# MBS288949

Other Notes

Small volumes of Ednra elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ednra. It may not necessarily be applicable to this product.

NCBI GI #
45383740
NCBI GeneID
13617
NCBI Accession #
NP_034462.1
UniProt Primary Accession #
Q61614
UniProt Secondary Accession #
O54993; Q91VV2
UniProt Related Accession #
Q61614
GenBank Nucleotide #
NM_010332.2
NCBI Official Full Name
endothelin-1 receptor
NCBI Official Synonym Full Names
endothelin receptor type A
NCBI Official Symbol
Ednra
NCBI Official Synonym Symbols
ETa; ET-AR; Gpcr10
UniProt Protein Name
Endothelin-1 receptor
UniProt Synonym Protein Names
Endothelin A receptor; ET-A; ET-AR
Protein Family
Endothelin-1 receptor
UniProt Gene Name
Ednra
UniProt Synonym Gene Names
Gpcr10; ET-A; ET-AR
UniProt Entry Name
EDNRA_MOUSE
NCBI Protein Information
endothelin-1 receptor

UniProt Comments for Ednra

EDNRA: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Motility/polarity/chemotaxis; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Cellular Component: cytosol; integral to membrane; lipid raft; membrane; nuclear membrane; plasma membrane; T-tubule

Molecular Function: endothelin receptor activity; G-protein coupled receptor activity; protein binding; protein-tyrosine kinase activity; signal transducer activity

Biological Process: artery smooth muscle contraction; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); enteric nervous system development; fibroblast proliferation; G-protein coupled receptor protein signaling pathway; glomerular filtration; glucose transport; heart development; histamine secretion; in utero embryonic development; negative regulation of apoptosis; negative regulation of cAMP biosynthetic process; neural crest cell development; patterning of blood vessels; penile erection; positive regulation of calcium ion transport; positive regulation of cell proliferation; positive regulation of inflammatory response; positive regulation of odontogenesis; positive regulation of protein amino acid phosphorylation; positive regulation of release of sequestered calcium ion into cytosol; protein kinase C activation; regulation of blood pressure; regulation of epithelial cell proliferation; respiratory gaseous exchange; response to hypoxia; response to lipopolysaccharide; response to morphine; Rho protein signal transduction; sensory perception of pain; signal transduction; smooth muscle cell proliferation; vasoconstriction
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Research Articles on Ednra

1. Venous Edn1 guides stellate ganglia axons to innervate the developing heart via Ednra on those axons. Edn1-Ednra signalling is essential for functional regulation of the heart by sympathetic nerves.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ednra elisa kit

 Reference Product  PubMed Publications
 Edn1 elisa kit  >52 publications with Ednra and Edn1
 Ednrb elisa kit  >45 publications with Ednra and Ednrb
 Edn2 elisa kit  >13 publications with Ednra and Edn2
 Edn3 elisa kit  >9 publications with Ednra and Edn3
 Plcb1 elisa kit  >1 publications with Ednra and Plcb1

Pathways associated with Ednra elisa kit

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with Ednra elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >23 publications with Ednra and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >21 publications with Ednra and Nervous System Diseases
 Hypertension Antibodies  >17 publications with Ednra and Hypertension
 Craniofacial Abnormalities Antibodies  >12 publications with Ednra and Craniofacial Abnormalities
 Lung Diseases Antibodies  >12 publications with Ednra and Lung Diseases
 Inflammation Antibodies  >8 publications with Ednra and Inflammation
 Disease Models, Animal Antibodies  >6 publications with Ednra and Disease Models, Animal
 Kidney Diseases Antibodies  >5 publications with Ednra and Kidney Diseases
 Hypertension, Pulmonary Antibodies  >5 publications with Ednra and Hypertension, Pulmonary
 Atherosclerosis Antibodies  >5 publications with Ednra and Atherosclerosis

Organs/Tissues associated with Ednra elisa kit

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >17 publications with Ednra and Embryonic Tissue
 Lung Antibodies  >12 publications with Ednra and Lung
 Kidney Antibodies  >10 publications with Ednra and Kidney
 Heart Antibodies  >10 publications with Ednra and Heart
 Ovary Antibodies  >8 publications with Ednra and Ovary
 Eye Antibodies  >7 publications with Ednra and Eye
 Brain Antibodies  >5 publications with Ednra and Brain
 Joint Antibodies  >5 publications with Ednra and Joint
 Connective Tissue Antibodies  >4 publications with Ednra and Connective Tissue
 Prostate Antibodies  >2 publications with Ednra and Prostate
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