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Appetite-Regulating Hormone (GHRL) ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS289519

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.Principle of the Assay: The microtiter plate… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Appetite-regulating hormone (Ghrl), ELISA Kit
Full Product Name
Rat Appetite-regulating hormone ELISA Kit
Product Gene Name
Ghrl elisa kit
Product Synonym Names
Appetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Ghrl
Species Reactivity
Rat
Samples
Serum, Plasma, Tissue Homogenates, Cell Culture Supernates Or Other Biological Fluids.
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
13,048 Da
3D Structure
ModBase 3D Structure for Q9QYH7

Typical Testing Data/Standard Curve (for reference only) of Ghrl elisa kit

Rat GHRL ELISA Kit – Cat# MBS289519

Other Notes

Small volumes of Ghrl elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ghrl purchase

MBS289519 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Appetite-regulating hormone (Ghrl) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Ghrl. The ELISA analytical biochemical technique of the MBS289519 kit is based on Ghrl antibody-Ghrl antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Ghrl antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Ghrl. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for Ghrl. It may not necessarily be applicable to this product.

NCBI GI #
11067387
NCBI GeneID
59301
NCBI Accession #
NP_067701.1
UniProt Primary Accession #
Q9QYH7
UniProt Secondary Accession #
Q9ET69
UniProt Related Accession #
Q9QYH7
GenBank Nucleotide #
NM_021669.2
NCBI Official Full Name
appetite-regulating hormone preproprotein
NCBI Official Synonym Full Names
ghrelin/obestatin prepropeptide
NCBI Official Symbol
Ghrl
UniProt Protein Name
Appetite-regulating hormone
UniProt Synonym Protein Names
Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide
Protein Family
Appetite-regulating hormone
UniProt Gene Name
Ghrl
UniProt Entry Name
GHRL_RAT
NCBI Protein Information
appetite-regulating hormone

NCBI Summary for Ghrl

endogenous ligand for the growth hormone secretagogue receptor (GHSR); involved in testicular function and GH release [RGD, Feb 2006]

UniProt Comments for Ghrl

ghrelin: a hormone that binds to the growth hormone secretagogue receptor type 1 (GHSR). Secreted by the stomach

Protein type: Secreted, signal peptide; Cell development/differentiation; Secreted; Cell cycle regulation; Apoptosis

Cellular Component: axon; cytoplasm; cytosol; extracellular region; extracellular space

Molecular Function: G-protein-coupled receptor binding; ghrelin receptor binding; growth hormone-releasing hormone activity; hormone activity; protein tyrosine kinase activator activity

Biological Process: actin polymerization and/or depolymerization; activation of MAPK activity; adult feeding behavior; decidualization; dendrite development; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; gastric acid secretion; hormone-mediated signaling; negative regulation of apoptosis; negative regulation of circadian sleep/wake cycle, REM sleep; negative regulation of endothelial cell proliferation; negative regulation of inflammatory response; negative regulation of insulin secretion; negative regulation of interleukin-1 beta production; negative regulation of interleukin-6 biosynthetic process; negative regulation of locomotion; negative regulation of tumor necrosis factor biosynthetic process; positive regulation of adrenocorticotropic hormone secretion; positive regulation of appetite; positive regulation of circadian sleep/wake cycle, non-REM sleep; positive regulation of cortisol secretion; positive regulation of growth hormone secretion; positive regulation of insulin secretion; positive regulation of response to food; positive regulation of synaptogenesis; regulation of cell proliferation; regulation of excitatory postsynaptic membrane potential; regulation of response to food; response to estrogen stimulus; response to hormone stimulus
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Research Articles on Ghrl

1. may act primarily via a central pathway within the brain to suppress sympathetic nerve activity after myocardial infarction

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ghrl elisa kit

 Reference Product  PubMed Publications
 Ghsr elisa kit  >32 publications with Ghrl and Ghsr
 Lep elisa kit  >13 publications with Ghrl and Lep
 Cck elisa kit  >10 publications with Ghrl and Cck
 Gcg elisa kit  >3 publications with Ghrl and Gcg
 Igf1 elisa kit  >1 publications with Ghrl and Igf1
 Mboat4 elisa kit  >1 publications with Ghrl and Mboat4
 Ins1 elisa kit  >1 publications with Ghrl and Ins1

Pathways associated with Ghrl elisa kit

 Products by Pathway  Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Synthesis, Secretion, And Deacylation Of Ghrelin Pathway antibodies  Synthesis, Secretion, And Deacylation Of Ghrelin Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram

Diseases associated with Ghrl elisa kit

 Disease Name  Pubmed Publications
 Obesity Antibodies  >62 publications with Ghrl and Obesity
 Insulin Resistance Antibodies  >19 publications with Ghrl and Insulin Resistance
 Cardiovascular Diseases Antibodies  >16 publications with Ghrl and Cardiovascular Diseases
 Weight Loss Antibodies  >16 publications with Ghrl and Weight Loss
 Weight Gain Antibodies  >14 publications with Ghrl and Weight Gain
 Inflammation Antibodies  >12 publications with Ghrl and Inflammation
 Cachexia Antibodies  >8 publications with Ghrl and Cachexia
 Breast Neoplasms Antibodies  >7 publications with Ghrl and Breast Neoplasms
 Kidney Diseases Antibodies  >6 publications with Ghrl and Kidney Diseases
 Necrosis Antibodies  >5 publications with Ghrl and Necrosis
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